Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Burge Ulukan"'
Autor:
Ozge Saatci, Rashedul Alam, Kim-Tuyen Huynh-Dam, Aynur Isik, Meral Uner, Nevin Belder, Pelin Gulizar Ersan, Unal Metin Tokat, Burge Ulukan, Metin Cetin, Kubra Calisir, Mustafa Emre Gedik, Hilal Bal, Ozlem Sener Sahin, Yasser Riazalhosseini, Denis Thieffry, Daniel Gautheret, Besim Ogretmen, Sercan Aksoy, Aysegul Uner, Aytekin Akyol, Ozgur Sahin
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-14 (2024)
Abstract Tamoxifen has been the mainstay therapy to treat early, locally advanced, and metastatic estrogen receptor-positive (ER + ) breast cancer, constituting around 75% of all cases. However, the emergence of resistance is common, necessitating th
Externí odkaz:
https://doaj.org/article/736322c0c13e4be88e8c36818fc7c5ab
Autor:
Mujdat Zeybel, Muhammad Arif, Xiangyu Li, Ozlem Altay, Hong Yang, Mengnan Shi, Murat Akyildiz, Burcin Saglam, Mehmet Gokhan Gonenli, Buket Yigit, Burge Ulukan, Dilek Ural, Saeed Shoaie, Hasan Turkez, Jens Nielsen, Cheng Zhang, Mathias Uhlén, Jan Borén, Adil Mardinoglu
Publikováno v:
Advanced Science, Vol 9, Iss 11, Pp n/a-n/a (2022)
Abstract Metabolic dysfunction‐associated fatty liver disease (MAFLD) is a complex disease involving alterations in multiple biological processes regulated by the interactions between obesity, genetic background, and environmental factors including
Externí odkaz:
https://doaj.org/article/f0323763de524d1baed15e3811c0095e
Publikováno v:
ACS Omega, Vol 5, Iss 43, Pp 28273-28284 (2020)
Externí odkaz:
https://doaj.org/article/4b5f90af4fc142d587d087d1664b05d4
Publikováno v:
Medical Sciences, Vol 7, Iss 2, p 24 (2019)
Transglutaminase 2 (TG2) is a multifunctional crosslinking enzyme that displays transamidation, protein disulfide isomerase, protein kinase, as well as GTPase and ATPase activities. TG2 can also act as an adhesion molecule involved in the syndecan an
Externí odkaz:
https://doaj.org/article/201e8dfdb7824e5ab0c55e3f56a4de8d
Autor:
Buket Yigit, Ekin Ozgonul, Omer Yaman, Burge Ulukan, Yagmur Cetin Tas, Berna Morova, Musa Aydin, Yigit Uysalli, Elif Demirtas, Mert Erkan, Yasemin Gursoy Ozdemir, Sercin Karahuseyinoglu, Cihan Yurdaydin, Murat Akyildiz, Abhishek Sheth, Hale Kirimlioglu, Murat Dayangac, Onur Ferhanoglu, Alper Kiraz, Mujdat Zeybel
Background and aims: Liver fibrosis is a dynamic process of fibrogenesis and fibrolysis traditionally evaluated by liver biopsy. Accurate assessment of hepatic fibrosis is vital for optimal biomarker and drug development in the era of NASH clinical t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7baec850081ea2a2c850ecdd791ae85
https://hdl.handle.net/20.500.12511/9645
https://hdl.handle.net/20.500.12511/9645
Publikováno v:
Current Opinion in Pharmacology. 49:102-109
Fibroblasts have a central role in tissue fibrosis and fibrotic diseases. Fibroblast activation is regulated by several mechanisms including epigenetic modifications; histone modifications, DNA methylation and non-coding RNAs. Although research has s
Autor:
Buket Yiğit, Ozlem Altay, Shi M, Mehmet Gokhan Gonenli, Adil Mardinoglu, Jens Nielsen, Burge Ulukan, Burcin Saglam, Zeybel M, Xin Li, Cheng Zhang, Saeed Shoaie, Mathias Uhlén, Jan Borén, Dilek Ural, Muhammad Arif, Hasan Turkez, Murat Akyildiz
Non-alcoholic fatty liver disease (NAFLD) is a complex disease involving alterations in multiple biological processes regulated by the interactions between obesity, genetic background and environmental factors including the microbiome. To decipher he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8510b3bcbc1299c432bdf0740580e9ba
https://doi.org/10.1101/2021.05.22.21257482
https://doi.org/10.1101/2021.05.22.21257482
Autor:
Ebru Yilmaz, Alisan Kayabolen, Semra Cemre Atalar, Buket Yigit, Burge Ulukan, Mujdat Zeybel, Tugba Bagci-Onder
Publikováno v:
Cancer Research. 82:6255-6255
Induction of apoptosis in cancer cells via de-repressing dormant pro-apoptotic genes might be a successful therapeutic strategy. In this study, we utilized several dCas9-mediated CRISPR activation (CRISPRa) systems to activate two key pro-apoptotic g
Publikováno v:
Medical Sciences
Medical Sciences, Vol 7, Iss 2, p 24 (2019)
Medical Sciences, Vol 7, Iss 2, p 24 (2019)
Transglutaminase 2 (TG2) is a multifunctional crosslinking enzyme that displays transamidation, protein disulfide isomerase, protein kinase, as well as GTPase and ATPase activities. TG2 can also act as an adhesion molecule involved in the syndecan an
Autor:
Burge Ulukan, Melis Cansu Cömert, Mert Erkan, Müjdat Zeybel, Buket Yiğit, Onur Yılmaz, Murat Dayangac, Gupse Adalı
Publikováno v:
Journal of Hepatology. 70:e549
International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL) -- APR 10-14, 2019 -- Vienna, AUSTRIA