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Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality.

Autor: Shi T; Division of Immunobiology and.; Immunology Graduate Program, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Medical Scientist Training Program and., Burg AR; Division of Immunobiology and.; Division of Transplantation, Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Caldwell JT; Division of Nephrology and Hypertension and., Roskin KM; Division of Immunobiology and.; Divison of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Castro-Rojas CM; Division of Immunobiology and., Chukwuma PC; Department of Chemistry and Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, Indiana, USA., Gray GI; Department of Chemistry and Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, Indiana, USA., Foote SG; Department of Chemistry and Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, Indiana, USA., Alonso JA; Department of Chemistry and Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, Indiana, USA., Cuda CM; Northwestern University, Feinberg School of Medicine, Department of Medicine, Division of Rheumatology, Chicago, Illinois, USA., Allman DA; University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Rush JS; Novartis Institutes for Biomedical Research, Immunology Disease Area, Basel, Switzerland., Regnier CH; Novartis Institutes for Biomedical Research, Immunology Disease Area, Basel, Switzerland., Wieczorek G; Novartis Institutes for Biomedical Research, Immunology Disease Area, Basel, Switzerland., Alloway RR; Division of Nephrology and Hypertension, Department of Internal Medicine, and., Shields AR; Division of Transplantation, Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Baker BM; Department of Chemistry and Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, Indiana, USA., Woodle ES; Division of Transplantation, Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Hildeman DA; Division of Immunobiology and.; Immunology Graduate Program, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Medical Scientist Training Program and.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2023 Jul 17; Vol. 133 (14). Date of Electronic Publication: 2023 Jul 17.

MDA5-dependent responses contribute to autoimmune diabetes progression and hindrance.

Autor: Blum SI; Department of Microbiology, Comprehensive Diabetes Center, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Taylor JP; Department of Microbiology, Comprehensive Diabetes Center, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Barra JM; Department of Microbiology, Comprehensive Diabetes Center, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Burg AR; Department of Microbiology, Comprehensive Diabetes Center, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Shang Q; Department of Microbiology, Comprehensive Diabetes Center, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Qiu S; Department of Microbiology, Comprehensive Diabetes Center, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Shechter O; Department of Microbiology, Comprehensive Diabetes Center, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Hayes AR; Department of Microbiology, Comprehensive Diabetes Center, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Green TJ; Department of Microbiology, Comprehensive Diabetes Center, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Geurts AM; Department of Physiology and., Chen YG; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Tse HM; Department of Microbiology, Comprehensive Diabetes Center, The University of Alabama at Birmingham, Birmingham, Alabama, USA.

Publikováno v: JCI insight [JCI Insight] 2023 Jan 24; Vol. 8 (2). Date of Electronic Publication: 2023 Jan 24.

Auranofin-Mediated NRF2 Induction Attenuates Interleukin 1 Beta Expression in Alveolar Macrophages.

Autor: Wall SB; Neonatal Redox Biology Laboratory, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; Division of Neonatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Li R; Neonatal Redox Biology Laboratory, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; Division of Neonatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Butler B; Section of Neonatology, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO 80045, USA., Burg AR; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Tse HM; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Larson-Casey JL; Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Carter AB; Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; Birmingham Veterans Affairs Medical Center, Birmingham, AL 35233, USA., Wright CJ; Section of Neonatology, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO 80045, USA.; Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO 80045, USA., Rogers LK; Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43215, USA., Tipple TE; Section of Neonatal-Perinatal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

Publikováno v: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2021 Apr 21; Vol. 10 (5). Date of Electronic Publication: 2021 Apr 21.

Commensal Candida albicans Positively Calibrates Systemic Th17 Immunological Responses.

Autor: Shao TY; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Ang WXG; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Jiang TT; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Huang FS; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Andersen H; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Kinder JM; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Pham G; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Burg AR; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Ruff B; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Gonzalez T; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Khurana Hershey GK; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Haslam DB; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA., Way SS; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA. Electronic address: singsing.way@cchmc.org.

Publikováno v: Cell host & microbe [Cell Host Microbe] 2019 Mar 13; Vol. 25 (3), pp. 404-417.e6.