An assessment of the factors affecting the commercialization of cell-based therapeutics: a systematic review protocol

Autor: Pettitt, D, Arshaad, Z, Davies, B, Smith, J, French, A, Cole, D, Bure, K, Dopson, S, DiGiusto, D, Karp, J, Reeve, B, Barker, R, Holländer, G, Brindley, DB

Publikováno v: Systematic Reviews, Vol 6, Iss 1, Pp 1-6 (2017)
BioMed Central
Systematic Reviews

Background - Cellular-based therapies represent a platform technology within the rapidly expanding field of regenerative medicine and are distinct from conventional therapeutics—offering a unique approach to managing what were once considered untre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8ec0e704cc9ed9b4e9f06b62f2e6eae6
http://link.springer.com/article/10.1186/s13643-017-0517-4

Emerging platform bioprocesses for viral vectors and gene therapies

Autor: Pettitt, D, Smith, JA, Fuerstenau-Sharp, M, Bure, K, Holländer, G, Predki, P, Slade, A, Jones, P, Mitrophanous, K, Brindley, D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::589ab7524a3b2bf536d81e60b5a72e31
https://ora.ox.ac.uk/objects/uuid:e7fc39c3-9d50-4a64-8d85-7e0f24ef3225

Quantitative assessment of barriers to the clinical development and adoption of cellular therapies: A pilot study

Autor: Davies, B, Rikabi, S, French, A, Pinedo-Villanueva, R, Morrey, M, Wartolowska, K, Judge, A, Maclaren, R, Mathur, A, Williams, D, Wall, I, Birchall, M, Reeve, B, Atala, A, Barker, R, Cui, Z, Furniss, D, Bure, K, Snyder, E, Karp, J, Price, A, Carr, A, Brindley, D

Publikováno v: Journal of Tissue Engineering
Journal of Tissue Engineering, Vol 5 (2014)

There has been a large increase in basic science activity in cell therapy and a growing portfolio of cell therapy trials. However, the number of industry products available for widespread clinical use does not match this magnitude of activity. We hyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9d57b56affeee8b9ab695ff2a1921086
http://europepmc.org/articles/PMC4221931

Bioprocess decision support tool for scalable manufacture of extracellular vesicles.

Autor: Ng KS; Harvard-MIT Division of Health Sciences and Technology, Cambridge, Massachusetts.; Division of Engineering in Medicine, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA.; Harvard Stem Cell Institute, Cambridge, Massachusetts.; RoosterBio, Frederick, Maryland., Smith JA; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.; The Oxford-UCL Centre for the Advancement of Sustainable Medical Innovation, University of Oxford, Oxford, UK., McAteer MP; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts., Mead BE; Harvard-MIT Division of Health Sciences and Technology, Cambridge, Massachusetts.; Division of Engineering in Medicine, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA.; Harvard Stem Cell Institute, Cambridge, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.; Koch Institute for Integrative Cancer Research, MIT, Cambridge, Massachusetts., Ware J; The Oxford-UCL Centre for the Advancement of Sustainable Medical Innovation, University of Oxford, Oxford, UK., Jackson FO; The Oxford-UCL Centre for the Advancement of Sustainable Medical Innovation, University of Oxford, Oxford, UK., Carter A; Department of Paediatrics, University of Oxford, Oxford, UK., Ferreira L; University of Coimbra, Center for Neuroscience and Cell Biology, Portugal., Bure K; The Oxford-UCL Centre for the Advancement of Sustainable Medical Innovation, University of Oxford, Oxford, UK., Rowley JA; RoosterBio, Frederick, Maryland., Reeve B; Harvard Stem Cell Institute, Cambridge, Massachusetts., Brindley DA; Harvard Stem Cell Institute, Cambridge, Massachusetts.; The Oxford-UCL Centre for the Advancement of Sustainable Medical Innovation, University of Oxford, Oxford, UK.; Department of Paediatrics, University of Oxford, Oxford, UK.; Centre for Behavioural Medicine, UCL School of Pharmacy, University College London, London, UK.; UCSF-Stanford Center of Excellence in Regulatory Science and Innovation, San Francisco, California., Karp JM; Harvard-MIT Division of Health Sciences and Technology, Cambridge, Massachusetts.; Division of Engineering in Medicine, Department of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, MA.; Harvard Stem Cell Institute, Cambridge, Massachusetts.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts.

Publikováno v: Biotechnology and bioengineering [Biotechnol Bioeng] 2019 Feb; Vol. 116 (2), pp. 307-319. Date of Electronic Publication: 2018 Nov 08.

Bioprocessing automation in cell therapy manufacturing: Outcomes of special interest group automation workshop.

Autor: Ball O; Biolacuna, Oxford, UK. Electronic address: oliver.ball@biolacuna.com., Robinson S; Biolacuna, Oxford, UK., Bure K; AveriCELL, Northborough, MA, USA., Brindley DA; Department of Paediatrics, University of Oxford, Oxford, UK. Electronic address: david.brindley@paediatrics.ox.ac.uk., Mccall D; Phacilitate, London, UK.

Publikováno v: Cytotherapy [Cytotherapy] 2018 Apr; Vol. 20 (4), pp. 592-599. Date of Electronic Publication: 2018 Feb 13.