Anakinra for palmoplantar pustulosis: results from a randomized, double-blind, multicentre, two-staged, adaptive placebo-controlled trial (APRICOT)

Autor: Cro, S, Cornelius, VR, Pink, AE, Wilson, R, Pushpa-Rajah, A, Patel, P, Abdul-Wahab, A, August, S, Azad, J, Becher, G, Chapman, A, Dunnil, G, Ferguson, AD, Fogo, A, Ghaffar, SA, Ingram, JR, Kavakleiva, S, Ladoyanni, E, Leman, JA, Macbeth, AE, Makrygeoegou, A, Parslew, R, Ryan, AJ, Sharma, A, Shipman, AR, Sinclair, C, Wachsmuth, R, Woolf, RT, Wright, A, McAteer, H, Barker, JNWN, Burden, AD, Griffiths, CEM, Reynolds, NJ, Warren, RB, Lachmann, HJ, Capon, F, Smith, CH, APRICOT Study Group

Publikováno v: The British journal of dermatology.

BACKGROUND Palmoplantar pustulosis (PPP) is a rare, debilitating, chronic inflammatory skin disease that affects the hands and feet. Clinical, immunological and genetic findings suggest a pathogenic role for interleukin (IL)-1. OBJECTIVES To determin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab57fe1a0bd3e580fd96eb5a45add84
https://pubmed.ncbi.nlm.nih.gov/34878653

Association of Serum Ustekinumab Levels With Clinical Response in Psoriasis

Autor: Tsakok, T, Wilson, N, Dand, N, Loeff, FC, Bloem, K, Baudry, D, Duckworth, M, Pan, S, Pushpa-Rajah, A, Standing, JF, de Vries, A, Alsharqi, A, Becher, G, Murphy, R, Wahie, S, Wright, A, Griffiths, CEM, Reynolds, NJ, Barker, J, Warren, RB, Burden, AD, Rispens, T, Stocken, D, Smith, C, British Association of Dermatologists Biologic and Immunomodulat, Psoriasis Stratification to Optimise Relevant Therapy (PSORT) Co

Importance: High-cost biologic therapies have transformed the management of immune-mediated inflammatory diseases. To optimize outcomes and reduce costs, dose adjustment informed by measurement of circulating drug levels has been shown to be effectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::57ac2b7f151499f6af850762b558b365
https://eprints.whiterose.ac.uk/158276/1/jamadermatology_tsakok_2019_oi_190040.pdf

Defining the therapeutic range for adalimumab and predicting response in psoriasis: a multicenter prospective observational cohort study

Autor: Wilkinson, N, Tsakok, T, Dand, N, Bloem, K, Duckworth, M, Baudry, D, Pushpa-Rajah, A, Griffiths, CE, Reynolds, N, Barker, J, Warren, RB, Burden, AD, Rispens, T, Stocken, D, Smith, C, BSTOP study group and PSORT consortium

Biologics have transformed management of inflammatory diseases. To optimize outcomes and reduce costs, dose adjustment informed by circulating drug levels has been proposed. We aimed to determine the real-world clinical utility of therapeutic drug mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::cd5c9ad38c620e6104a874efa5435a15

Clinical and genetic differences between pustular psoriasis subtypes

Autor: Twelves, S, Mostafa, A, Dand, N, Burri, E, Farkas, K, Wilson, R, Cooper, HL, Irvine, AD, Oon, HH, Kingo, K, Koks, S, Mrowietz, U, Puig, L, Reynolds, N, Tan, EST, Tanew, A, Torz, K, Trattner, H, Valentine, M, Wahie, S, Warren, RB, Wright, A, Bata-Csorgo, Z, Szell, M, Griffiths, CEM, Burden, AD, Choon, SE, Smith, CH, Barker, JN, Navarini, AA, Capon, F

Publikováno v: Twelves, S, Mostafa, A, Dand, N, Burri, E, Farkas, K, Wilson, R, Cooper, H L, Irvine, A D, Oon, H H, Kingo, K, Köks, S, Mrowietz, U, Puig, L, Reynolds, N, Tan, E S-T, Tanew, A, Torz, K, Trattner, H, Valentine, M, Wahie, S, Warren, R B, Wright, A, Bata-Csörgő, Z, Szell, M, Griffiths, C E M, Burden, A D, Choon, S-E, Smith, C H, Barker, J N, Navarini, A A & Capon, F 2018, ' Clinical and genetic differences between pustular psoriasis subtypes ', The Journal of allergy and clinical immunology, vol. 143, no. 3, pp. 1021-1026 . https://doi.org/10.1016/j.jaci.2018.06.038
The Journal of Allergy and Clinical Immunology
Twelves, S, Mostafa, A, Dand, N, Burri, E, Farkas, K, Wilson, R, Cooper, H L, Irvine, A D, Oon, H H, Kingo, K, Köks, S, Mrowietz, U, Puig, L, Reynolds, N, Sern-Ting Tan, E, Tanew, A, Torz, K, Trattner, H, Valentine, M, Wahie, S, Warren, R B, Wright, A, Bata-Csörgő, Z, Szell, M, Griffiths, C EM, Burden, A D, Choon, S-E, Smith, C H, Barker, J N, Navarini, A A & Capon, F 2018, ' Clinical and genetic differences between pustular psoriasis subtypes ', Journal of Allergy and Clinical Immunology, vol. 143, no. 3, pp. 1021-1026 . https://doi.org/10.1016/j.jaci.2018.06.038
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Background The term pustular psoriasis indicates a group of severe skin disorders characterized by eruptions of neutrophil-filled pustules. The disease, which often manifests with concurrent psoriasis vulgaris, can have an acute systemic (generalized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6e51b5fbca1dd92f9d0d367fc6192f7d
https://doi.org/10.1016/j.jaci.2018.06.038

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.