Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Burcu Özçimen"'
Autor:
Özgür Dogus Erol, Burcu Pervin, Mehmet Emin Şeker, Burcu Özçimen, Şimal Şenocak, Sema Nur Gür, Hasan Basri Kiliç, Merve Gizer, Petek Korkusuz, Nico Peter van Til, Yusuf Çetin Kocaefe, Fatima Aerts Kaya
Publikováno v:
HemaSphere, Vol 7, p e37198af (2023)
Externí odkaz:
https://doaj.org/article/a0c1f33184514a73ad55aa4b5356ba3a
Autor:
Deniz Uğurlu-Çimen, Deniz Odluyurt, Kenan Sevinç, Nazlı Ezgi Özkan-Küçük, Burcu Özçimen, Deniz Demirtaş, Eray Enüstün, Can Aztekin, Martin Philpott, Udo Oppermann, Nurhan Özlü, Tamer T. Önder
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-13 (2021)
Abstract Background The histone H3 lysine 79 (H3K79) methyltransferase DOT1L is a key chromatin-based barrier to somatic cell reprogramming. However, the mechanisms by which DOT1L safeguards cell identity and somatic-specific transcriptional programs
Externí odkaz:
https://doaj.org/article/6c418758198f4fd28da489c60812d32b
Autor:
Simge Kelekçi, Deniz Uğurlu-Çimen, Ata Berk Demir, Burcu Özçimen, Abdullah Burak Yıldız, Mehmet Batuhan Karakuş, Esra Börklü Yücel, Tamer T. Önder
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102438- (2021)
Friedreich’s ataxia (FRDA) is a rare neurodegenerative disorder which is caused by triplet repeat expansion (GAA) in the first intron of FXN gene. In this present study, we generated induced pluripotent stem cells (iPSC) lines from fibroblasts of t
Externí odkaz:
https://doaj.org/article/af1bdc2abc0e4420a2018db899eef4c3
Autor:
Can Aztekin, Deniz Uğurlu-Çimen, Martin Philpott, Eray Enustun, Deniz Odluyurt, Burcu Özçimen, Nurhan Özlü, Deniz Demirtaş, Nazlı Ezgi Özkan-Küçük, Kenan Sevinç, Tamer T. Onder, Udo Oppermann
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-13 (2021)
Epigenetics and Chromatin
Epigenetics & Chromatin
Epigenetics and Chromatin
Epigenetics & Chromatin
Background: the histone H3 lysine 79 (H3K79) methyltransferase DOT1L is a key chromatin-based barrier to somatic cell reprogramming. However, the mechanisms by which DOT1L safeguards cell identity and somatic-specific transcriptional programs remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90210daeae1c8661cefeda2ed97ee708
https://zenodo.org/record/5069041
https://zenodo.org/record/5069041
Autor:
Tamer T. Onder, Simge Kelekçi, Abdullah Burak Yıldız, Mehmet Batuhan Karakuş, Ata Berk Demir, Burcu Özçimen, Esra Börklü Yücel, Deniz Uğurlu-Çimen
Publikováno v:
Stem Cell Research
Stem Cell Research, Vol 54, Iss, Pp 102438-(2021)
Stem Cell Research, Vol 54, Iss, Pp 102438-(2021)
Friedreich's ataxia (FRDA) is a rare neurodegenerative disorder which is caused by triplet repeat expansion (GAA) in the first intron of FXN gene. In this present study, we generated induced pluripotent stem cells (iPSC) lines from fibroblasts of thr
Autor:
Kenan Sevinç, Tamer T. Onder, Martin Philpott, Burcu Özçimen, Nazlı Ezgi Özkan-Küçük, Udo Oppermann, Deniz Odluyurt, Nurhan Özlü, Can Aztekin, Eray Enustun, Deniz Demirtaş, Deniz Uğurlu-Çimen
SummaryThe histone H3 lysine 79 (H3K79) methyltransferase DOT1L is a key chromatin-based barrier to somatic cell reprogramming. However, the mechanisms by which DOT1L safeguards cell identity and somatic-specific transcriptional programs remain unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63f0705fe2241cec6a5988ed77822cdb
https://doi.org/10.1101/2020.12.22.423908
https://doi.org/10.1101/2020.12.22.423908
Publikováno v:
Cell Death & Disease
Cell Death and Disease
Cell Death and Disease, Vol 11, Iss 8, Pp 1-14 (2020)
Cell Death and Disease
Cell Death and Disease, Vol 11, Iss 8, Pp 1-14 (2020)
Complete hydatidiform mole (HM) is a gestational trophoblastic disease resulting in hyperproliferation of trophoblast cells and absence of embryo development. Mutations in the maternal-effect gene NLRP7 are the major cause of familial recurrent compl
Autor:
Tamer T. Onder, Kubra Nur Kaplan, Nur Arslan, Alper Bagriyanik, Eray Enustun, Burcu Özçimen, Onur Basak, Soheil Akbari, Kenan Sevinç, Gülben Gürhan Sevinç, Erkin Ozel, Esra Erdal, Nevin Ersoy, Berke Sengun
Publikováno v:
Stem Cell Reports
Summary Organoid technologies have become a powerful emerging tool to model liver diseases, for drug screening, and for personalized treatments. These applications are, however, limited in their capacity to generate functional hepatocytes in a reprod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039c50c108b012372541f2a59c452074
https://aperta.ulakbim.gov.tr/record/75351
https://aperta.ulakbim.gov.tr/record/75351
Autor:
Burcu Özçimen, Ali Cihan Taskin, Tamer T. Onder, Gizem Nur Sahin, Ahmet Kocabay, Sercin Karahuseyinoglu, Arzu Ruacan, Ayyub Ebrahimi
Leptin, a metabolic hormone, regulates the reproductive functions responding to both nutritional and body conditions. Embryonic stem cells play important roles in reproductive technology, but their derivation can be challenging. In this study, we eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2b62e36b3c1f58cb631f41c9922a60
https://aperta.ulakbim.gov.tr/record/70155
https://aperta.ulakbim.gov.tr/record/70155
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1353
Induced pluripotent stem cells (iPSCs) offer great promise as tools for basic biomedical research, disease modeling, and drug screening. In this chapter, we describe the generation of patient-specific, transgene-free iPSCs from skin biopsies and peri