Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Burchelle, Blackman"'
Autor:
Olga Kim, Zach Sergi, Guangyang Yu, Kazutoshi Yamamoto, Martha Quezado, Zied Abdullaev, Danel R. Crooks, Shun Kishimoto, Qi Li, Peng Lu, Burchelle Blackman, Thorkell Andresson, Xiaolin Wu, Bao Tran, Jun S. Wei, Wei Zhang, Meili Zhang, Hua Song, Javed Khan, Murali C. Krishna, Jeffrey R. Brender, Jing Wu
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Malignant transformation (MT) is commonly seen in IDH-mutant gliomas. There has been a growing research interest in revealing its underlying mechanisms and intervening prior to MT at the early stages of the transforming process. Here we esta
Externí odkaz:
https://doaj.org/article/4b329e13fa87456ea2628bbe4d0bfe40
Autor:
Burchelle Blackman, Natarajan Raju, Chandrasekhar Mushti, Kelly Lane, Daxeshkumar Patel, Curtis Harris, Rolf E. Swenson
Publikováno v:
Molecules, Vol 29, Iss 12, p 2781 (2024)
An untargeted metabolomic study identified four potential lung cancer diagnostic biomarkers in human urine. One of the potential biomarkers was an unidentified feature possessing a m/z value of 561+. “561+” was isolated from human urine and tenta
Externí odkaz:
https://doaj.org/article/57a4bc11429f48a2bac0c4d8948c46e0
Autor:
Kazutoshi Yamamoto, Ana Opina, Deepak Sail, Burchelle Blackman, Keita Saito, Jeffrey R. Brender, Ronja M. Malinowski, Tomohiro Seki, Nobu Oshima, Daniel R. Crooks, Shun Kishimoto, Yu Saida, Yasunori Otowa, Peter L. Choyke, Jan H. Ardenkjær-Larsen, James B. Mitchell, W. Marston Linehan, Rolf E. Swenson, Murali C. Krishna
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Drastic sensitivity enhancement of dynamic nuclear polarization is becoming an increasingly critical methodology to monitor real-time metabolic and physiological information in chemistry, biochemistry, and biomedicine. However, the limited n
Externí odkaz:
https://doaj.org/article/bad8b5268826453db750b84fe20d286f
Autor:
Ganesh Shenoy, Jessica Ettedgui, Chandrasekhar Mushti, Jennifer Hong, Kelly Lane, Burchelle Blackman, Hak-Sung Jung, Yasuharu Takagi, Yeonee Seol, Martin Brechbiel, Rolf E. Swenson, Keir C. Neuman
Publikováno v:
Molecules, Vol 27, Iss 3, p 736 (2022)
Carboxylic acid is a commonly utilized functional group for covalent surface conjugation of carbon nanoparticles that is typically generated by acid oxidation. However, acid oxidation generates additional oxygen containing groups, including epoxides,
Externí odkaz:
https://doaj.org/article/91899c4937144cb1b89a2b0ff27e4b3f
Autor:
Chandrasekhar Mushti, Kazutoshi Yamamoto, Rolf E. Swenson, Tomohiro Seki, Natsuko Miura, Burchelle Blackman, Jenna E. AbuSalim, Murali C. Krishna, Aparna H. Kesarwala, Jeffrey R. Brender, Kevin Camphausen
Publikováno v:
ACS Chemical Biology. 16:2144-2150
Alpha-ketoglutarate (α-KG) is a key metabolite and signaling molecule in cancer cells, but the low permeability of α-KG limits the study of α-KG mediated effects in vivo. Recently, cell-permeable monoester and diester α-KG derivatives have been s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ce7c9d15c9c2066b6c94448327a5a11
https://doi.org/10.1021/acschembio.1c00561
https://doi.org/10.1021/acschembio.1c00561
Autor:
Falguni Basuli, Xiang Zhang, Burchelle Blackman, Margaret E. White, Elaine M. Jagoda, Peter L. Choyke, Rolf E. Swenson
Publikováno v:
Molecules, Vol 24, Iss 13, p 2389 (2019)
To further explore the scope of our recently developed “fluorination on Sep-Pak” method, we prepared two well-known positron emission tomography (PET) tracers 21-[18F]fluoro-16α,17α-[(R)-(1′-α-furylmethylidene)dioxy]-19-norpregn-4-ene-3,20-d
Externí odkaz:
https://doaj.org/article/24e12dca25e44a03a7d3eee4668d131c
Autor:
Jenna E, AbuSalim, Kazutoshi, Yamamoto, Natsuko, Miura, Burchelle, Blackman, Jeffrey R, Brender, Chandrasekhar, Mushti, Tomohiro, Seki, Kevin A, Camphausen, Rolf E, Swenson, Murali C, Krishna, Aparna H, Kesarwala
Publikováno v:
ACS Chem Biol
Alpha-ketoglutarate (α-KG) is a key metabolite and signaling molecule in cancer cells, but the low permeability of α-KG limits the study of α-KG mediated effects in vivo. Recently, cell-permeable monoester and diester α-KG derivatives have been s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b759913442a19c03bd92ae2bdd533512
https://pubmed.ncbi.nlm.nih.gov/34554724
https://pubmed.ncbi.nlm.nih.gov/34554724
Autor:
Burchelle Blackman, Deepak Sail, Kazutoshi Yamamoto, Shingo Matsumoto, Shun Kishimoto, Murali Krishna, Keita Saito, James Mitchell, Jeffrey R. Brender, Rolf E. Swenson
Publikováno v:
Free Radical Biology and Medicine. 131:18-26
Effective means to identify the role of reactive oxygen species (ROS) mediating several diseases including cancer, ischemic heart disease, stroke, Alzheimer’s and other inflammatory conditions in in vivo models would be useful. The cyclic nitrone 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57bc173174973a986093bb7e51c20ed
https://doi.org/10.1016/j.freeradbiomed.2018.11.013
https://doi.org/10.1016/j.freeradbiomed.2018.11.013
Autor:
Shun Kishimoto, Yasunori Otowa, Keita Saito, Daniel R. Crooks, Deepak Sail, Ana Christina L. Opina, Murali C. Krishna, Yu Saida, Jan Henrik Ardenkjær-Larsen, Ronja Maja Malinowski, Peter L. Choyke, James B. Mitchell, Nobu Oshima, Kazutoshi Yamamoto, W. Marston Linehan, Jeffrey R. Brender, Burchelle Blackman, Tomohiro Seki, Rolf E. Swenson
Publikováno v:
Scientific Reports
Yamamoto, K, Opina, A, Sail, D, Blackman, B, Saito, K, Brender, J R, Malinowski, R M, Seki, T, Oshima, N, Crooks, D R, Kishimoto, S, Saida, Y, Otowa, Y, Choyke, P L, Ardenkjær-Larsen, J H, Mitchell, J B, Linehan, W M, Swenson, R E & Krishna, M C 2021, ' Real-Time insight into in vivo redox status utilizing hyperpolarized [1-13C] N-acetyl cysteine ', Scientific Reports, vol. 11, no. 1, 12155 . https://doi.org/10.1038/s41598-021-90921-0
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Yamamoto, K, Opina, A, Sail, D, Blackman, B, Saito, K, Brender, J R, Malinowski, R M, Seki, T, Oshima, N, Crooks, D R, Kishimoto, S, Saida, Y, Otowa, Y, Choyke, P L, Ardenkjær-Larsen, J H, Mitchell, J B, Linehan, W M, Swenson, R E & Krishna, M C 2021, ' Real-Time insight into in vivo redox status utilizing hyperpolarized [1-13C] N-acetyl cysteine ', Scientific Reports, vol. 11, no. 1, 12155 . https://doi.org/10.1038/s41598-021-90921-0
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Drastic sensitivity enhancement of dynamic nuclear polarization is becoming an increasingly critical methodology to monitor real-time metabolic and physiological information in chemistry, biochemistry, and biomedicine. However, the limited number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121b009991a5f5d6d56c8f0c16445e52
http://europepmc.org/articles/PMC8190077
http://europepmc.org/articles/PMC8190077
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 61:427-437
Traditional radiosynthetic optimization faces the challenges of high radiation exposure, cost, and inability to perform serial reactions due to tracer decay. To accelerate tracer development, we have developed a strategy to simulate radioactive 18 F-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e45891bb0d8c97764c929f6d56849574
https://doi.org/10.1002/jlcr.3606
https://doi.org/10.1002/jlcr.3606