Structural Elucidation and Absolute Stereochemistry for Pharma Compounds Using MicroED.

Autor: de Moraes LS; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Burch JE; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.; Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.; MicroEDLab.com, 1623 Central Avenue Suite 18, Cheyenne, Wyoming 82001, United States., Delgadillo DA; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Rodriguez IH; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Mai H; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Smith AG; Drug Substance Technologies - Synthetics, Process Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Caille S; Drug Substance Technologies - Synthetics, Process Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Walker SD; Drug Substance Technologies - Synthetics, Process Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Wurz RP; Medicinal Chemistry, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Cee VJ; Medicinal Chemistry, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Rodriguez JA; Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States., Gostovic D; MicroEDLab.com, 1623 Central Avenue Suite 18, Cheyenne, Wyoming 82001, United States., Quasdorf K; Drug Substance Technologies - Synthetics, Process Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States., Nelson HM; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.; Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.

Publikováno v: Organic letters [Org Lett] 2024 Aug 23; Vol. 26 (33), pp. 6944-6949. Date of Electronic Publication: 2024 Aug 08.

High-Throughput Identification of Crystalline Natural Products from Crude Extracts Enabled by Microarray Technology and microED.

Autor: Delgadillo DA; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Burch JE; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Kim LJ; Department of Chemistry and Biochemistry, and Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, California 90095, United States., de Moraes LS; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Niwa K; Department of Chemistry and Biochemistry, and Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, California 90095, United States., Williams J; Department of Chemistry and Biochemistry, and Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, California 90095, United States., Tang MJ; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Lavallo VG; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Khatri Chhetri B; School of Biological Sciences, School of Chemistry and Biochemistry, and Neuroscience Program, Georgia Institute of Technology, Atlanta, Georgia 30332, United States., Jones CG; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Rodriguez IH; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Signore JA; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Marquez L; Molecular and Systems Pharmacology, Laney Graduate School, Emory University, Atlanta, Georgia 30322, United States., Bhanushali R; School of Biological Sciences, School of Chemistry and Biochemistry, and Neuroscience Program, Georgia Institute of Technology, Atlanta, Georgia 30332, United States., Woo S; Center for the Study of Human Health, Emory University, Atlanta, Georgia 30322, United States., Kubanek J; School of Biological Sciences, School of Chemistry and Biochemistry, and Neuroscience Program, Georgia Institute of Technology, Atlanta, Georgia 30332, United States., Quave C; Molecular and Systems Pharmacology, Laney Graduate School, Emory University, Atlanta, Georgia 30322, United States.; Center for the Study of Human Health, Emory University, Atlanta, Georgia 30322, United States.; Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia 30322, United States., Tang Y; Department of Chemistry and Biochemistry, and Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, California 90095, United States.; Department of Chemistry and Biochemistry, and Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, California 90095, United States., Nelson HM; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

Publikováno v: ACS central science [ACS Cent Sci] 2023 Dec 20; Vol. 10 (1), pp. 176-183. Date of Electronic Publication: 2023 Dec 20 (Print Publication: 2024).

Cryptic Chemical Variation in a Marine Red Alga as Revealed by Nontargeted Metabolomics.

Autor: Khatri Chhetri B; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.; Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia 30332, United States., Mojib N; Department of Biology, Spelman College, Atlanta, Georgia 30314, United States., Moore SG; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332, United States., Delgadillo DA; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Burch JE; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Barrett NH; School of Earth and Atmospheric Sciences, Atlanta, Georgia 30332, United States., Gaul DA; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332, United States., Marquez L; Department of Dermatology, Center for the Study of Human Health, and Antibiotic Resistance Center, Emory University, Atlanta, Georgia 30322, United States., Soapi K; Institute of Applied Sciences, University of South Pacific, Suva, Fiji., Nelson HM; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States., Quave CL; Department of Dermatology, Center for the Study of Human Health, and Antibiotic Resistance Center, Emory University, Atlanta, Georgia 30322, United States., Kubanek J; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.; Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.

Publikováno v: ACS omega [ACS Omega] 2023 Apr 06; Vol. 8 (15), pp. 13899-13910. Date of Electronic Publication: 2023 Apr 06 (Print Publication: 2023).

Predictors of faculty narrative evaluation quality in medical school clerkships.

Autor: Mooney CJ; School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA., Pascoe JM; School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA., Blatt AE; School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA., Lang VJ; School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA., Kelly MS; Massachusetts General Hospital, Boston, Massachusetts, USA., Braun MK; School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA., Burch JE; School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA., Stone RT; School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA.

Publikováno v: Medical education [Med Educ] 2022 Dec; Vol. 56 (12), pp. 1223-1231. Date of Electronic Publication: 2022 Aug 23.

Identification of Uric Acid Gluconucleoside-Ascaroside Conjugates in Caenorhabditis elegans by Combining Synthesis and MicroED.

Autor: Curtis BJ; Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States., Kim LJ; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Wrobel CJJ; Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States., Eagan JM; Ascribe Bioscience, Ithaca, New York 14853, United States., Smith RA; Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States., Burch JE; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Le HH; Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States., Artyukhin AB; Chemistry Department, College of Environmental Science and Forestry, State University of New York, Syracuse, New York 13210, United States., Nelson HM; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States., Schroeder FC; Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States.

Publikováno v: Organic letters [Org Lett] 2020 Sep 04; Vol. 22 (17), pp. 6724-6728. Date of Electronic Publication: 2020 Aug 21.