Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Burce Ergel"'
Autor:
Parinati Kharel, Jacqueline Burré, Milen Velinov, Nima N. Naseri, Manu Sharma, Natalia Dolzhanskaya, Rong Huang, Burce Ergel, Qingqiu Huang, Yoonmi Na
Publikováno v:
Nature structural & molecular biology
Point mutations in cysteine string protein-α (CSPα) cause dominantly inherited adult-onset neuronal ceroid lipofuscinosis (ANCL), a rapidly progressing and lethal neurodegenerative disease with no treatment. ANCL mutations are proposed to trigger C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856ae3c6b665673b561e08966ca0f93b
https://doi.org/10.1038/s41594-020-0375-y
https://doi.org/10.1038/s41594-020-0375-y
Autor:
Andrea Olga Andrea Olga Shorts, Aaron P. Yamniuk, Keith S. Bahjat, Radha Ramakrishnan, Gaëlle Martin, Sanjib Dutta, David A Critton, Hua Fang, Dibella Rose A, Kader Thiam, Lynne Campbell, Arathi Krishnakumar, Burce Ergel, Martin J. Corbett, Haibin Chen, Robert J. Johnston, Richard Y.-C. Huang, Alan J. Korman, Joseph M. Rizzo, Thomas Cayton, Zheng Yang, Michael Quigley, Jason Pinckney, Ying-Kai Wang, Ginger Rakestraw, Justine Ngo, Paul O. Sheppard, Linhui Julie Su, Andrew Rankin, Jim Holloway, Xiaodi Deng, Akbar Nayeem, Arvind Rajpal, Eric Boyer, Hadia Lemar, Alexander T. Kozhich
Publikováno v:
Nature. 574:565-570
Co-inhibitory immune receptors can contribute to T cell dysfunction in patients with cancer1,2. Blocking antibodies against cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death 1 (PD-1) partially reverse this effect and are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f81db0a515c56824b63859d10463a7
https://doi.org/10.1038/s41586-019-1674-5
https://doi.org/10.1038/s41586-019-1674-5
Publikováno v:
The Journal of biological chemistry. 289(43)
A central goal of enzymology is to understand the physicochemical mechanisms that enable proteins to catalyze complex chemical reactions with high efficiency. Recent methodological advances enable the contribution of protein dynamics to enzyme effici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3b3c1752632f8ef991e5b4a5478863
https://pubmed.ncbi.nlm.nih.gov/25043760
https://pubmed.ncbi.nlm.nih.gov/25043760
Autor:
David Mu, Scott Powers, Burce Ergel, Rajasekhar Singavarapu, Sandra Orsulic, Jiangyong Miao, Esther Oliva, Zhenfeng Duan
Publikováno v:
International journal of cancer. 123(9)
Hepsin is a serine protease that is widely expressed in different tissues and cell types, most prominently in the normal liver and kidney. Overexpression of hepsin has been associated with prostate cancers, ovarian cancers and renal cell carcinomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30dd5395d44134330e2bc76eb4070bac
https://pubmed.ncbi.nlm.nih.gov/18726901
https://pubmed.ncbi.nlm.nih.gov/18726901
Autor:
Ramy Farid, Chiara Pastore, John F. Hunt, Brian R. Gibney, Burce Ergel, Bomina Yu, Richard A. Friesner, Gregory Liebisch, William Edstrom
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44f549b4f8dbfe83ad49dd55dd11121f
https://doi.org/10.1096/fasebj.22.1_supplement.526.3
https://doi.org/10.1096/fasebj.22.1_supplement.526.3