Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Burak T. Kaynak"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1577-1586 (2020)
Despite the wealth of methods developed for exploring the molecular basis of allostery in biomolecular systems, there is still a need for structure-based predictive tools that can efficiently detect susceptible sites for triggering allosteric respons
Externí odkaz:
https://doaj.org/article/be05410b332a4156ad0045ff06a18975
Autor:
Burak T. Kaynak, James M. Krieger, Balint Dudas, Zakaria L. Dahmani, Mauricio G. S. Costa, Erika Balog, Ana Ligia Scott, Pemra Doruker, David Perahia, Ivet Bahar
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Recent years have seen several hybrid simulation methods for exploring the conformational space of proteins and their complexes or assemblies. These methods often combine fast analytical approaches with computationally expensive full atomic molecular
Externí odkaz:
https://doaj.org/article/902b2f3af6304360bc36b423da15694c
Publikováno v:
Bioinformatics. 39
Motivation Allostery enables changes to the dynamic behavior of a protein at distant positions induced by binding. Here, we present APOP, a new allosteric pocket prediction method, which perturbs the pockets formed in the structure by stiffening pair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3520c61f77ee67231b3a9fb70b5c6682
https://doi.org/10.1093/bioinformatics/btad275
https://doi.org/10.1093/bioinformatics/btad275
Autor:
Burak T. Kaynak, Zakaria L. Dahmani, Pemra Doruker, Anupam Banerjee, Shang-Hua Yang, Reuven Gordon, Laura S. Itzhaki, Ivet Bahar
Publikováno v:
Structure. 31:607-618.e3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88deadf5238205b56271e96a6892bdd5
https://doi.org/10.1016/j.str.2023.02.012
https://doi.org/10.1016/j.str.2023.02.012