Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Burak I. Arioz"'
Autor:
Christina Morgenstern, Isabel Lastres-Becker, Birsen Can Demirdöğen, Vera Marisa Costa, Andreas Daiber, Roberta Foresti, Roberto Motterlini, Sibel Kalyoncu, Burak I. Arioz, Sermin Genc, Monika Jakubowska, Ioannis P. Trougakos, Aleksandra Piechota-Polanczyk, Michel Mickael, Marlene Santos, Thomas W. Kensler, Antonio Cuadrado, Ian M. Copple
Publikováno v:
Redox Biology, Vol 72, Iss , Pp 103134- (2024)
The cytoprotective transcription factor NRF2 regulates the expression of several hundred genes in mammalian cells and is a promising therapeutic target in a number of diseases associated with oxidative stress and inflammation. Hence, an ability to mo
Externí odkaz:
https://doaj.org/article/f50d81e6b4e544bc8942767d3919a61a
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The NLRP3 inflammasome is an intracellular multiprotein complex that plays an essential role in the innate immune system by identifying and eliminating a plethora of endogenous and exogenous threats to the host. Upon activation of the NLRP3 complex,
Externí odkaz:
https://doaj.org/article/ced448a2a20044bfa54832009c613d0b
Autor:
Bora Tastan, Burak I. Arioz, Kemal Ugur Tufekci, Emre Tarakcioglu, Ceren Perihan Gonul, Kursad Genc, Sermin Genc
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
NLRP3 inflammasome activation contributes to several pathogenic conditions, including lipopolysaccharide (LPS)-induced sickness behavior characterized by reduced mobility and depressive behaviors. Dimethyl fumarate (DMF) is an immunomodulatory and an
Externí odkaz:
https://doaj.org/article/b60a1794759e426ca70953d604e6e91d
Autor:
Burak I. Arioz, Bora Tastan, Emre Tarakcioglu, Kemal Ugur Tufekci, Melis Olcum, Nevin Ersoy, Alper Bagriyanik, Kursad Genc, Sermin Genc
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Inflammation is a crucial component of various stress-induced responses that contributes to the pathogenesis of major depressive disorder (MDD). Depressive-like behavior (DLB) is characterized by decreased mobility and depressive behavior that occurs
Externí odkaz:
https://doaj.org/article/24e7f872c8254d2b95f741e379e21522
Publikováno v:
Neurochemical Research. 47:3202-3211
Systemic inflammation can have devastating effects on the central nervous system via its resident immune cells, the microglia. One of the primary mediators of this inflammation is inflammasomes, multiprotein complexes that trigger a release of inflam