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A validated prognostic classifier for V600EBRAF-mutated metastatic colorectal cancer: the ‘BRAF BeCool’ study

Autor: Loupakis F., Intini R., Cremolini C., Orlandi A., Sartore-Bianchi A., Pietrantonio F., Pella N., Spallanzani A., Dell'Aquila E., Scartozzi M., De Luca E., Rimassa L., Formica V., Leone F., Calvetti L., Aprile G., Antonuzzo L., Urbano F., Prenen H., Negri F., Di Donato S., Buonandi P., Tomasello G., Avallone A., Zustovich F., Moretto R., Antoniotti C., Salvatore L., Calegari M. A., Siena S., Morano F., Ongaro E., Cascinu S., Santini D., Ziranu P., Schirripa M., Buggin F., Prete A. A., Depetris I., Biason P., Lonardi S., Zagonel V., Fassan M., Di Maio M.

Background: Despite the well-known negative prognostic value of the V600EBRAF mutation in patients with metastatic colorectal cancer (mCRC), its outcome is quite heterogeneous, and the basis for this prognostic heterogeneity should be better defined.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::843eef4f2889f5dea40981dd561ad931
http://hdl.handle.net/11568/1021597

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Liquid biopsy using ascitic fluid and pleural effusion supernatants for genomic profiling in gastrointestinal and lung cancers.

Autor: Wu, Huita^1,2,3 (AUTHOR), Ji, Haonan¹ (AUTHOR), Yang, Wenhui⁴ (AUTHOR), Zhang, Min^5,6 (AUTHOR), Guo, Yifang⁷ (AUTHOR), Li, Bangkai⁸ (AUTHOR), Wang, Jiayin⁵ (AUTHOR), Chen, Rongrong⁶ (AUTHOR), Chen, Yuan⁹ (AUTHOR) chenyuan008@163.com, Wang, Xin¹ (AUTHOR) szzj1997@163.com

Publikováno v: BMC Cancer. 9/27/2022, Vol. 22 Issue 1, p1-10. 10p.

The autocrine loop of ALK receptor and ALKAL2 ligand is an actionable target in consensus molecular subtype 1 colon cancer.

Autor: Mazzeschi, Martina¹ (AUTHOR), Sgarzi, Michela¹ (AUTHOR), Romaniello, Donatella¹ (AUTHOR), Gelfo, Valerio¹ (AUTHOR), Cavallo, Carola² (AUTHOR), Ambrosi, Francesca³ (AUTHOR), Morselli, Alessandra¹ (AUTHOR), Miano, Carmen⁴ (AUTHOR), Laprovitera, Noemi¹ (AUTHOR), Girone, Cinzia¹ (AUTHOR), Ferracin, Manuela¹ (AUTHOR), Santi, Spartaco^5,6 (AUTHOR), Rihawi, Karim⁷ (AUTHOR), Ardizzoni, Andrea^1,7 (AUTHOR), Fiorentino, Michelangelo¹ (AUTHOR), D'Uva, Gabriele^1,4 (AUTHOR), Győrffy, Balázs^8,9 (AUTHOR), Palmer, Ruth¹⁰ (AUTHOR), Lauriola, Mattia^1,11 (AUTHOR) mattia.lauriola2@unibo.it

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 3/29/2022, Vol. 41 Issue 1, p1-18. 18p.