Zobrazeno 1 - 10
of 1 115
pro vyhledávání: '"Bunyatyan, A."'
Autor:
Pavel A. Galenko-Yaroshevsky, Olga V. Shelemekh, Viktor L. Popkov, Andrey V. Zadorozhniy, Irina B. Nektarevskaya, Natalia D. Bunyatyan, Roman A. Murashko, Svetlana A. Lebedeva, Anait V. Zelenskaya, Aleksandr V. Uvarov, Olga N. Gulevskaya, Lusine O. Alukhanyan, Tereza R. Glechyan, Alina V. Sergeeva, Alina V. Kornetskaya, Nikolay E. Korovaykin
Publikováno v:
Research Results in Pharmacology, Vol 10, Iss 1, Pp 23-43 (2024)
Introduction: Although nonsteroidal anti-inflammatory drugs (NSAIDs) have a clear therapeutic benefit, they can also have serious side effects. The most serious of these is the ulcerogenic effect, which can result in a decline in the quality of life
Externí odkaz:
https://doaj.org/article/20e84e18beac4a2cb8b2e31e37c12aaf
Publikováno v:
Антибиотики и Химиотерапия, Vol 68, Iss 9-10, Pp 42-45 (2024)
The created cell line of human proximal renal tubules RPTEC/TERT1 showed maximum compliance with primary human RPTEC, which makes it optimal for use in studies of the nephrotoxic properties of xenobiotics. Transepithelial resistance measurement (TEER
Externí odkaz:
https://doaj.org/article/198e692a97c5411991524a972ddefc21
Publikováno v:
Безопасность и риск фармакотерапии, Vol 11, Iss 4, Pp 423-429 (2023)
Scientific relevance. Favipiravir is an antiviral RNA polymerase inhibitor used to treat COVID-19. An adverse drug reaction associated with the use of favipiravir is renal disorder.Aim. This study aimed to investigate favipiravir nephrotoxicity by as
Externí odkaz:
https://doaj.org/article/ab94cd0ba4254feea1a60b46ec074b98
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 13, Iss 4, Pp 560-566 (2023)
Scientific relevance. Sound recommendations for preclinical studies of transporter- mediated pharmacokinetic interactions of medicinal products can help increase the likelihood of identifying potentially nephrotoxic and hepatotoxic medicinal products
Externí odkaz:
https://doaj.org/article/5bc7522fe58e440495aa3bba1c8efed9
Autor:
Pavel A. Galenko-Yaroshevsky, Aleksandr А. Slavinskiy, Sergey S. Todorov, Viktor L. Popkov, Olga V. Shelemekh, Svetlana A. Lebedeva, Andrey V. Zadorozhniy, Anait V. Zelenskaya, Lusine O. Alukhanyan, Irina B. Nektarevskaya, Natalia D. Bunyatyan, Aleksandr А. Verevkin
Publikováno v:
Research Results in Pharmacology, Vol 9, Iss 4, Pp 1-12 (2023)
Introduction: Combined inflammatory and destructive processes affecting the dental pulp and tissues of the periodontal complex are among the most problem diseases of the dental system. Current therapy with use of available pharmacological agents does
Externí odkaz:
https://doaj.org/article/27d8059aa08c4b2ca27ac981aa7ab79c
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 13, Iss 3, Pp 385-393 (2023)
Scientific relevance. Hypromellose phthalate is used in enteric coatings for oral medicinal products. The proportion of phthalate groups in the polymer is standardised because it has a significant effect on solubility. Whereas, the molecular mass of
Externí odkaz:
https://doaj.org/article/7825b42082a24a59acff8c71688c56d7
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 13, Iss 2-1, Pp 316-332 (2023)
Liposomes are one of the most well-known and promising nanoscale drug delivery systems. Liposomal medicinal products are successfully used in clinical practice for cardiovascular, oncological, dermatological, and other indications. The development of
Externí odkaz:
https://doaj.org/article/4e60d2a7f704403587226ef2e5845e80
Publikováno v:
Безопасность и риск фармакотерапии, Vol 11, Iss 2, Pp 155-164 (2023)
Researchers need to identify the nephrotoxic properties of medicinal products both during preclinical development and when exploring options to optimise pharmacotherapy. The main challenge is to find an experimental model for assessing drug-induced n
Externí odkaz:
https://doaj.org/article/03f2bd56b57149c6b57cb088a9b70633
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 13, Iss 1, Pp 112-120 (2023)
Being widely used, medicinal products based on vegetable oils require strict regulation and evaluation of quality attributes, determination of shelf-life periods, and monitoring of storage conditions. The most common testing method for unsaturated co
Externí odkaz:
https://doaj.org/article/316cb81bce8f42a9989df1539ea68de2
Autor:
G. F. Vasilenko, L. M. Krasnykh, M. V. Zhuravleva, A. B. Prokofiev, G. I. Gorodetskaya, V. V. Smirnov, N. D. Bunyatyan
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 12, Iss 3, Pp 331-340 (2022)
The relationship between dissolution and bioavailability is an example of the interdependency between the quality of a medicinal product and its safety and efficacy. The uniqueness of thioctic acid is that it can exist in an oxidised and a reduced fo
Externí odkaz:
https://doaj.org/article/7607f125c1184eeb86aeddd7dcd3b6ea