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pro vyhledávání: '"Bunnarack Kuch"'
Autor:
Jeni Gerberich, Ralph P. Mason, Bunnarack Kuch, Blake A. Winn, Mary Lynn Trawick, Zhe Shi, Matthew T. MacDonough, Alejandro J. Ramirez, Tracy E. Strecker, Peter David Davis, Laxman Devkota, Yifan Wang, Ernest Hamel, Deboprosad Mondal, David J. Chaplin, Kevin G. Pinney
Publikováno v:
J Nat Prod
The natural products combretastatin A-1 (CA1) and combretastatin A-4 (CA4) function as potent inhibitors of tubulin polymerization and as selective vascular disrupting agents (VDAs) in tumors. Bioreductively activatable prodrug conjugates (BAPCs) can