Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Bunichiro Ogawa"'
Autor:
Shohei Oyama, Kosuke Ebina, Yuki Etani, Makoto Hirao, Masanao Kyuuma, Yasuyuki Fujii, Katsuya Iwata, Bunichiro Ogawa, Tomoya Hasegawa, Sasagu Kawano, Yutaka Nakanishi, Seiji Okada, Ken Nakata
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract In clinical studies, the next-generation anti-tumor necrosis factor-alpha (TNF-α) single domain antibody ozoralizumab showed high clinical efficacy shortly after the subcutaneous injection. To elucidate the mechanism underlying the rapid on
Externí odkaz:
https://doaj.org/article/5ee7a27437214fe5a4e9c50bcc5d16fd
Autor:
Masanao Kyuuma, Ayaka Kaku, Chiemi Mishima-Tsumagari, Bunichiro Ogawa, Mayumi Endo, Yunoshin Tamura, Kei-ichiro Ishikura, Masashi Mima, Yutaka Nakanishi, Yasuyuki Fujii
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Biologics have become an important component of treatment strategies for a variety of diseases, but the immunogenicity of large immune complexes (ICs) and aggregates of biologics may increase risk of adverse events is a concern for biologics and it r
Externí odkaz:
https://doaj.org/article/93e7dbb80a1a452d968da965f61623be
Autor:
Bunichiro Ogawa1,2 b-ogawa@taisho.co.jp, Yutaka Nakanishi1, Masaki Wakamatsu1, Yasunori Takahashi2, Makoto Shibutani2,3
Publikováno v:
Journal of Toxicological Sciences. 2022, Vol. 47 Issue 11, p467-482. 16p.
Publikováno v:
Toxicology Letters. 378:1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6537f3eeab0463dcb20918dcc78fa5a
https://doi.org/10.1016/j.toxlet.2023.02.004
https://doi.org/10.1016/j.toxlet.2023.02.004
Autor:
Yasunori Takahashi, Hiromu Okano, Kazumi Takashima, Ryota Ojiro, Qian Tang, Shunsuke Ozawa, Bunichiro Ogawa, Gye-Hyeong Woo, Toshinori Yoshida, Makoto Shibutani
Publikováno v:
Toxicology Letters. 360:20-32
Drinking alcohol during pregnancy may cause fetal alcohol spectrum disorder. In rats, developmental exposure to ethanol (EtOH) at high doses has shown to induce aberrant neurogenesis in neural progenitor cells (NPCs) during weaning and suppress synap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b1d81a9bb2ab35f4ad8a2409409b15
https://doi.org/10.1016/j.toxlet.2022.02.006
https://doi.org/10.1016/j.toxlet.2022.02.006
Autor:
Hiromu Okano, Kazumi Takashima, Yasunori Takahashi, Ryota Ojiro, Qian Tang, Shunsuke Ozawa, Bunichiro Ogawa, Mihoko Koyanagi, Robert R. Maronpot, Toshinori Yoshida, Makoto Shibutani
Publikováno v:
Chemico-biological interactions. 351
The present study investigated the role of neuroinflammation and brain oxidative stress induced by neonatal treatment with lipopolysaccharides (LPS) on the development of autism spectrum disorder (ASD)-like behaviors and disruptive hippocampal neurog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b08141abd1de14715cee3f8e2e2d353
https://pubmed.ncbi.nlm.nih.gov/34863679
https://pubmed.ncbi.nlm.nih.gov/34863679
Publikováno v:
Journal of Toxicologic Pathology
When conducting histopathological evaluation of lymphoid tissues, it is necessary to know the variability and strain differences in histological features of different sites of lymphoid tissues. To investigate in detail the variability of lymphoid tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a423b3c64fc13b4b4d87c9abecbc59c
https://doi.org/10.1293/tox.2018-0052
https://doi.org/10.1293/tox.2018-0052
Autor:
Satomi Kikuchi, Qian Tang, Toshiya Okamura, Kazumi Takashima, Makoto Shibutani, Hiromu Okano, Bunichiro Ogawa, Toshinori Yoshida, Ryota Ojiro, Meilan Jin, Yasunori Takahashi, Tomoya Yoshinari
Publikováno v:
The Journal of toxicological sciences. 46(4)
Enniatins are so-called "emerging mycotoxins" that commonly occur in milligrams per kilogram levels in grains and their derived products, as well as in fish, dried fruits, nuts, spices, cocoa, and coffee. The present study investigated the 28-day rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def3e31222c9f5f3f8fe993990a3da31
https://pubmed.ncbi.nlm.nih.gov/33814509
https://pubmed.ncbi.nlm.nih.gov/33814509
Autor:
Aiko Ishii1 ai-ishii@so.taisho.co.jp, Bunichiro Ogawa1, Tomoko Koyama1, Yutaka Nakanishi1, Minoru Sasaki1
Publikováno v:
Journal of Toxicologic Pathology. 2017, Vol. 30 Issue 2, p161-168. 8p.
Autor:
Yasunori Takahashi, Kazumi Takashima, Toshinori Yoshida, Makoto Shibutani, Shunsuke Ozawa, Ryota Ojiro, Hiromu Okano, Qian Tang, Bunichiro Ogawa, Risako Yamashita, Gye-Hyeong Woo
Publikováno v:
Toxicology. 462:152958
Drinking alcohol during pregnancy may cause fetal alcohol spectrum disorder. The present study investigated the effects of maternal oral ethanol (EtOH) exposure (0, 10, or 12.5 % in drinking water) from gestational day 6 until day 21 post-delivery (w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fca09c58b400e2e734c75966d1fa26b
https://doi.org/10.1016/j.tox.2021.152958
https://doi.org/10.1016/j.tox.2021.152958