Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Bumpus Fm"'
Publikováno v:
Clinical & Experimental Hypertension. Part A: Theory & Practice; 1984, Vol. A6 Issue 10/11, p1749-1753, 5p
Publikováno v:
Clinical Science. 51:41-45
1. Adrenocorticotrophic hormone-suppressed, bilaterally nephrectomized male mongrel dogs (n = 12) were infused with Sar1-angiotensin II and Asp1-angiotensin II, the naturally occurring octapeptide. 2. Sar1-angiotensin II was found to be almost twice
Publikováno v:
Hypertension. 2:649-656
It has been suggested that in two-kidney, one clip hypertension, the undamped kidney (UK) actively contributes to hypertension by reducing its excretory ability in response to increased levels of Circulating angiotensin II. By exteriorizing the urete
Autor:
M. C. Khosla, Bumpus Fm
Publikováno v:
Clinical Science. 48:15s-18s
1. Competitive or non-competitive inhibition of the myotropic and pressor response of angiotensin II is dependent on the nature of the substituent in position 8 of the antagonist peptide analogue. Substituents in other positions of the molecule, part
Publikováno v:
American Journal of Physiology-Legacy Content. 228:110-114
Angiotensin II receptors in vascular smooth muscle and adrenal cortex have been characterized in the dog. The evidence was derived chiefly from experiments that assessed the ability of a structural analog of angiotensin II, [Sar1, Ile8] AII, to antag
Autor:
M. C. Khosla, Imai N, Yuichi Kumahara, Toshio Ogihara, Katsutoshi Katahira, Bumpus Fm, Hiroshi Mikami
Publikováno v:
Journal of Cardiovascular Pharmacology. 9:242-245
Among the various biological effects of angiotensin II (AII), both pressor activity and aldosterone stimulation appear to be mediated by functionally different receptors. With this in mind, we compared pressor and aldosterone-stimulating activities o
Publikováno v:
Clinical Science. 52:163-170
1. We describe a new method of producing two-kidney hypertension in dogs by a two-step procedure with complete occlusion of a renal artery 2 weeks after it was partially constricted. 2. Control mean arterial pressure (96 ± 3 mmHg) of nine conscious,
Autor:
Fumimaro Oseko, Ohmori Y, Ataru Taniguchi, Mahesh C. Khosla, Muranaka H, Hiroo Imura, Nakano R, Fumitake Ikeda, Bumpus Fm, Tsuyoshi Kono
Publikováno v:
Acta Endocrinologica. 99:577-584
The biololgical activity of des-asp1-,des-arg2-angiotensin II (3-8AII) was studied in man. When 3-8AII was infused iv at rates of 22 and 308 pmol (17.5 and 250 ng)/kg · min separately into 5 normal men each for 120 min, blood pressure showed no chan
Publikováno v:
Biochemistry. 6:3458-3464
Publikováno v:
Journal of the American Chemical Society. 70:3391-3394