Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Bum-Sang Shim"'
Autor:
Moon Nyeo Park, Hyunmin Park, Md. Ataur Rahman, Jeong Woo Kim, Se Sun Park, Yongmin Cho, Jinwon Choi, So-Ri Son, Dae Sik Jang, Bum-Sang Shim, Sung-Hoon Kim, Seong-Gyu Ko, Chunhoo Cheon, Bonglee Kim
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BK002 consists of Achyranthes japonica Nakai (AJN) and Melandrium firmum Rohrbach (MFR) that have been used as herbal medicines in China and Korea. AJN and MFR have been reported to have anti-inflammatory, anti-oxidative, and anti-cancer activities,
Externí odkaz:
https://doaj.org/article/5eb2a3dd2c7344a995c44a03266d43a2
Autor:
Suhyun Lim, Iwah Jeong, Jonghyeok Cho, Chaewon Shin, Kwan-Il Kim, Bum-Sang Shim, Seong-Gyu Ko, Bonglee Kim
Publikováno v:
Antioxidants, Vol 10, Iss 10, p 1524 (2021)
More than 500 million people suffer from allergic rhinitis (AR) in the world. Current treatments include oral antihistamines and intranasal corticosteroids; however, they often cause side effects and are unsuitable for long-term exposure. Natural pro
Externí odkaz:
https://doaj.org/article/94e94508717d43a38ac764643a556746
Autor:
Jae-Hee Lee, Dae-Young Lee, Hyo-Jung Lee, Eunji Im, Deok-Yong Sim, Ji-Eon Park, Woon-Yi Park, Bum-Sang Shim, Sung-Hoon Kim
Publikováno v:
Cells, Vol 10, Iss 8, p 2151 (2021)
Since the signal transducer and activator of transcription 3 (STAT3)/programmed death-ligand 1 (PD-L1) signaling plays an important role in tumor-immune microenvironments, in the present study, the role of STAT3/PD-L1 signaling in the apoptotic mecha
Externí odkaz:
https://doaj.org/article/1276735db6c847ee918e8e2752acb2b3
Autor:
Woon-Yi Park, Hyo-Jung Lee, Deok-Yong Sim, Eunji Im, Ji-Eon Park, Chi-Hoon Ahn, Bum-Sang Shim, Sung-Hoon Kim
Publikováno v:
Cells, Vol 10, Iss 8, p 2065 (2021)
Novel target therapy is on the spotlight for effective cancer therapy. Hence, in the present study, the underlying apoptotic mechanism of Morusin was explored in association with miR193a-5p mediated ZNF746/c-Myc signaling axis in colorectal cancer ce
Externí odkaz:
https://doaj.org/article/ca6dda1f2e1740449e0a51ef2d5e92f5
Autor:
Ji Eon Park, Chi-Hoon Ahn, Hyo-Jung Lee, Deok Yong Sim, Su Yeon Park, Bonglee Kim, Bum Sang Shim, Dae Young Lee, Sung-Hoon Kim
Publikováno v:
Antioxidants & Redox Signaling. 38:1101-1121
Drug induced liver injury (DILI) or hepatotoxicity has been a hot issue to overcome on the safety and physiological function of liver, since it is known to have biochemical, cellular, immunological and molecular alterations in liver mainly induced by
Autor:
Ji Eon Park, Woo‐Cheol Shin, Hyo‐Jung Lee, Dahye Yoon, Deok Yong Sim, Chi‐Hoon Ahn, Su‐Yeon Park, Bum Sang Shim, So Jung Park, Kyung Seok Kim, Geum Duck Park, Sung‐Hoon Kim, Dae Young Lee
Publikováno v:
Phytotherapy Research. 37:452-463
Autor:
Jin Young Suh, Hyo‐Jung Lee, Deok Yong Sim, Ji Eon Park, Chi‐Hoon Ahn, Su‐Yeon Park, Nari Shin, Bonglee Kim, Bum Sang Shim, Sung‐Hoon Kim
Publikováno v:
Phytotherapy Research. 37:7-14
Though icariside E4 (IE4) is known to have anti-noceptive, anti-oxidant, anti-Alzheimer and anti-inflammatory effects, there was no evidence on the effect of IE4 on lipid metabolism so far. Hence, the hypolipogenic mechanism of IE4 was investigated i
Autor:
Sung-Hoon Kim, Eunji Im, Deok Yong Sim, Ja Il Koo, Hyo-Jung Lee, Woon Yi Park, Jae Seok Yoon, Bum Sang Shim, Ji Eon Park
Publikováno v:
Phytotherapy Research. 35:6944-6953
Herein, apoptotic mechanism of Moracin D was explored in prostate cancer cells in association with peroxisome proliferator-activated receptor gamma (PPAR-γ)-related signaling involved in lipid metabolism. Moracin D augmented cytotoxicity and sub G1
Autor:
Ju-Ha Kim, Hee Young Kwon, Dong Hoon Ryu, Min-Ho Nam, Bum Sang Shim, Jin Han Kim, Jae Yeol Lee, Sung-Hoon Kim
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186490 (2017)
Though piperazine derivative BK10007S was known to induce apoptosis in pancreatic cancer xenograft model as a T-type CaV3.1 a1G isoform calcium channel blocker, its underlying antitumor mechanism still remains unclear so far. Thus, in the present stu
Externí odkaz:
https://doaj.org/article/14f8fa375a1d4b40ad20556b4ff7d068
Autor:
Ji Eon, Park, Woo-Cheol, Shin, Hyo-Jung, Lee, Dahye, Yoon, Deok Yong, Sim, Chi-Hoon, Ahn, Su-Yeon, Park, Bum Sang, Shim, So Jung, Park, Kyung Seok, Kim, Geum Duck, Park, Sung-Hoon, Kim, Dae Young, Lee
Publikováno v:
Phytotherapy research : PTRREFERENCES.
To target benign prostatic hyperplasia (BPH) as a common urinary disease in old men, in the current study, the antiproliferative and apoptotic mechanism of SH-PRO, a mixture of Angelica gigas and Astragalus membranaceus (2:1), was evaluated in BPH-1