Association between Clinical Frailty Scale and mortality 24 months after hospitalisation in adult patients with COVID-19

Autor: Julia Minnema, Melvin Lafeber, Roos S.G. Sablerolles, Janneke A.L. van Kempen, Lisanne Tap, Harmke A. Polinder-Bos, Bob P.A. van de Loo, Hugo van der Kuy, Miriam C. Faes, Jacomien Aleman, Jos Tournoy, Lorenz Van der Linden, Marco Gambera, Isabella Martignoni, Ronald Van Etten, Hein van Onzenoort, Mariette Kappers, Peter van Wijngaarden, Jose Verstijnen, Vera Theeuwes, Marleen Kemper, Elise Slob, Ferdi Sombogaard, Heshu Abdullah-Koolmees, Roland van den Berg, Hugo de Wit, Betul Dilek, Freija Hogenhuis, Vahid Buyukayten, Britt te Brake, Margriet Nieuwenhuijzen, Maria Scheeren, Madelief de Wit, Arjan Bulsink, Ingrid van Haelst, Peter ter Horst, Rosalie Moorlag, Anja Vos, Annemiek Otten-Helmers, Erik van Kan, Marije Voskamp, Marieke Ebbens, Marieke Ezinga, Cees van Nieuwkoop, Loes Visser, Caroline Ghazarian, Doranne Hilarius, Gonneke Hermanides, Carlinda Bresser, Judith Derijks-Engwegen, Ebbie Boemaars, Zahira Getrouw, Barbara Maat, Peter Wierenga, Tessa Bosch, Lisanne Krens, Kajie Liang, Langeza Saleh, Milou van Heuckelum, Linda Hendriksen, Paul van der Linden, Kaylen Guda, Kristel Crommentuijn, Ilse Cornelissen-Wesseling, Jeroen Diepstraten, Jacobien Ellerbroek, Saskia Coenradie, Debbie Deben, Kim Hurkens, Dennis Wong, Marion Vromen, Marjolein de Bock, Suzan Savelkoul, Saskia Wolters, Louise Andrews, Eefje Jong, Rosanne Kranenburg, Joana Soares, Fatima Falcao, Mariana Solano, Erica Viegas, Margarida Falcao, Helena Farinha, Dina Mendes, Joao Rijo, Marta Miarons, Maria Queralt Gorgas, Cristina García Yubero, Laura Portillo Horcajada, Kim Keijzers, Silke Lim, Linden Ashfield, Helen Bell, Naomi Fitzhugh, Glenda Fleming, Nicola Goodfellow, Joanne Hanley, Michael Scott, Simon P. Mooijaart, Jacobijn Gussekloo, Petra Elders, Geeske Peeters

Publikováno v: Heliyon, Vol 10, Iss 23, Pp e40456- (2024)

Background: The clinical frailty scale (CFS) was used as a triage tool for medical decision making during the COVID-19 pandemic. The CFS has been posed as a suitable risk marker for in-hospital mortality in COVID-19 patients. We evaluated whether the

Externí odkaz: https://doaj.org/article/c6e84359db6c419a80d153ef70cdacce

Dynamic loading leads to increased metabolic activity and spatial redistribution of viable cell density in nucleus pulposus tissue

Autor: Elias Salzer, Vivian H. M. Mouser, Jurgen A. Bulsink, Marianna A. Tryfonidou, Keita Ito

Publikováno v: JOR Spine, Vol 6, Iss 1, Pp n/a-n/a (2023)

Abstract Background Nucleus pulposus (NP) cell density is orchestrated by an interplay between nutrient supply and metabolite accumulation. Physiological loading is essential for tissue homeostasis. However, dynamic loading is also believed to increa

Externí odkaz: https://doaj.org/article/d7212d7a3e59473ea77ce9604b44b2b6

Association between Clinical Frailty Scale score and hospital mortality in adult patients with COVID-19 (COMET): an international, multicentre, retrospective, observational cohort study

Autor: Roos S G Sablerolles, MD, Melvin Lafeber, MD, Janneke A L van Kempen, MD, Bob P A van de Loo, Msc, Eric Boersma, ProfPhD, Wim J R Rietdijk, PhD, Harmke A Polinder-Bos, MD, Simon P Mooijaart, MD, Hugo van der Kuy, ProfPharmD, Jorie Versmissen, MD, Miriam C Faes, MD, LA Agnoletto, J Aleman, S Andreassi, LM Andrews, L Ashfield, H Bell, AKB Bengaard, SB Berlinghini, KB Bini, ZB Bisoffi, KB Blum, E Boemaars, GB Boni, TM Bosch, BE Bosma, F Boutkourt, C Bufarini, A Bulsink, RC Cabuk, GC Callens, MC Candela, MC Canonici, EC Capone, IC Carmo, FC Caruso, PC Chessa, GC Cohet, I Cornelissen-Wesseling, KML Crommentuijn, FM de Stoppelaar, HAJM de Wit, DS Deben, LJJ Derijks, MDC Di Carlo, J Diepstraten, B Dilek, DMK Duchek-Mann, MM Ebbens, LJ Ellerbroek, M Ezinga, MF Falcao, FF Falcao, LF Fantini, HF Farinha, PMG Filius, NJ Fitzhugh, G Fleming, TF Forsthuber, GG Gambarelli, MG Gambera, CGY García Yubero, Z Getrouw, CN Ghazarian, N Goodfellow, MQG Gorgas, RG Grinta, K Guda, DH Haider, J Hanley, KH Heitzeneder, WL Hemminga, LC Hendriksen, DL Hilarius, FEF Hogenhuis, IC Hoogendoorn-de Graaf, MBH Houlind, MAH Huebler, KPGM Hurkens, PKC Janssen, E Jong, MHW Kappers, KFM Keijzers, MK Kemogni, EM Kemper, RA Kranenburg, LL Krens, JL G Le Grand, J Liang, S Lim, NL Lindner, EL Loche, AL Lubich, B Maat, CM Maesano, AM Maiworm, M Maragna, FM Marchesini, IM Martignoni, G M Martini, CM Masini, R Mc Menamin, DM Mendes, M Miarons, R Moorlag, MR Müller, FN Nagele, KN Nemec, GO Oka, AG Otten-Helmers, SP Pagliarino, FP Pappalardo, M Patel, PM Peverini, FP Pieraccini, EMP Platania, NPK Pons-Kerjean, LPH Portillo Horcajada, GR Rametta, JR Rijo, EE Roelofsen, E Roobol-Meuwese, LR Rossi, SAH Russel, Z Safipour, FS Salaffi, L Saleh, AMS Schimizzi, JMGA Schols, MS Schwap, MG Scott, EAM Slijfer, EMA Slob, JS Soares, MS Solano, F Sombogaard, GS Stemer, MT Tardella, PGJ ter Horst, RT Tessari, J Tournoy, RB van den Berg, L Van der Linden, PD van der Linden, SC van Dijk, RW Van Etten, IMM van Haelst, M van Heuckelum, HJM van Kan, C van Nieuwkoop, HAW van Onzenoort, P van Wijngaarden, JDJ Verdonk, Fv Verri, JAMC Verstijnen, MV Veyrier, EV Viegas, LE Visser, A Vos, MAM Vromen, PC Wierenga, DR Wong, CZ Zenico, TZ Zuppini

Publikováno v: The Lancet. Healthy Longevity, Vol 2, Iss 3, Pp e163-e170 (2021)

Summary: Background: During the COVID-19 pandemic, the scarcity of resources has necessitated triage of critical care for patients with the disease. In patients aged 65 years and older, triage decisions are regularly based on degree of frailty measur

Externí odkaz: https://doaj.org/article/25542a489c0c438688fb4c4de1d44583

Fibronectin aggregates promote features of a classically and alternatively activated phenotype in macrophages

Autor: Arend H. Sikkema, Josephine M. J. Stoffels, Peng Wang, Frederike J. Basedow, Robbert Bulsink, Jeffrey J. Bajramovic, Wia Baron

Publikováno v: Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-17 (2018)

Abstract Background Means to promote endogenous remyelination in multiple sclerosis (MS) benefit from insights into the role of inhibitory molecules that preclude remyelination. Fibronectin assembles into aggregates in MS, which impair oligodendrocyt

Externí odkaz: https://doaj.org/article/b5ac1e2b50d540f0b9784401534f4c25

Oxygen Saturation Imaging Using LED-Based Photoacoustic System

Autor: Rianne Bulsink, Mithun Kuniyil Ajith Singh, Marvin Xavierselvan, Srivalleesha Mallidi, Wiendelt Steenbergen, Kalloor Joseph Francis

Publikováno v: Sensors, Vol 21, Iss 1, p 283 (2021)

Oxygen saturation imaging has potential in several preclinical and clinical applications. Dual-wavelength LED array-based photoacoustic oxygen saturation imaging can be an affordable solution in this case. For the translation of this technology, ther

Externí odkaz: https://doaj.org/article/fc01d691439946cea291780f03732012