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Akademický článek

Advances in menaquinone biosynthesis: sublocalisation and allosteric regulation.

Autor: Johnston JM; School of Physical and Chemical Sciences, Biomolecular Interaction Centre, and Maurice Wilkins Centre for MolecularBiodiscovery, University of Canterbury, Christchurch 8041, New Zealand. Electronic address: jodie.johnston@canterbury.ac.nz., Bulloch EM; Laboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for MolecularBiodiscovery, University of Auckland, Private Bag 92019, Auckland, New Zealand.

Publikováno v: Current opinion in structural biology [Curr Opin Struct Biol] 2020 Dec; Vol. 65, pp. 33-41. Date of Electronic Publication: 2020 Jul 05.

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Akademický článek

Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms.

Autor: Jirgis EN; Maurice Wilkins Centre for Molecular Biodiscovery, School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland 1010, New Zealand., Bashiri G; Maurice Wilkins Centre for Molecular Biodiscovery, School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland 1010, New Zealand., Bulloch EM; Maurice Wilkins Centre for Molecular Biodiscovery, School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland 1010, New Zealand., Johnston JM; Maurice Wilkins Centre for Molecular Biodiscovery, School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland 1010, New Zealand. Electronic address: jm.johnston@auckland.ac.nz., Baker EN; Maurice Wilkins Centre for Molecular Biodiscovery, School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland 1010, New Zealand. Electronic address: ted.baker@auckland.ac.nz.

Publikováno v: Structure (London, England : 1993) [Structure] 2016 Jul 06; Vol. 24 (7), pp. 1167-77. Date of Electronic Publication: 2016 Jun 09.

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Akademický článek

Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex.

Autor: Bashiri G; School of Biological Sciences, University of Auckland, 3a Symonds Steet, Private Bag 90210, Auckland 1142, New Zealand., Johnston JM; School of Biological Sciences, University of Auckland, 3a Symonds Steet, Private Bag 90210, Auckland 1142, New Zealand., Evans GL; School of Biological Sciences, University of Auckland, 3a Symonds Steet, Private Bag 90210, Auckland 1142, New Zealand., Bulloch EM; School of Biological Sciences, University of Auckland, 3a Symonds Steet, Private Bag 90210, Auckland 1142, New Zealand., Goldstone DC; School of Biological Sciences, University of Auckland, 3a Symonds Steet, Private Bag 90210, Auckland 1142, New Zealand., Jirgis EN; School of Biological Sciences, University of Auckland, 3a Symonds Steet, Private Bag 90210, Auckland 1142, New Zealand., Kleinboelting S; School of Biological Sciences, University of Auckland, 3a Symonds Steet, Private Bag 90210, Auckland 1142, New Zealand., Castell A; School of Biological Sciences, University of Auckland, 3a Symonds Steet, Private Bag 90210, Auckland 1142, New Zealand., Ramsay RJ; School of Biological Sciences, University of Auckland, 3a Symonds Steet, Private Bag 90210, Auckland 1142, New Zealand., Manos-Turvey A; School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia., Payne RJ; School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia., Lott JS; School of Biological Sciences, University of Auckland, 3a Symonds Steet, Private Bag 90210, Auckland 1142, New Zealand., Baker EN; School of Biological Sciences, University of Auckland, 3a Symonds Steet, Private Bag 90210, Auckland 1142, New Zealand.

Publikováno v: Acta crystallographica. Section D, Biological crystallography [Acta Crystallogr D Biol Crystallogr] 2015 Nov; Vol. 71 (Pt 11), pp. 2297-308. Date of Electronic Publication: 2015 Oct 31.

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Akademický článek

A covalent adduct of MbtN, an acyl-ACP dehydrogenase from Mycobacterium tuberculosis, reveals an unusual acyl-binding pocket.

Autor: Chai AF; Laboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand., Bulloch EM; Laboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand., Evans GL; Laboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand., Lott JS; Laboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand., Baker EN; Laboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand., Johnston JM; Laboratory of Structural Biology, School of Biological Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.

Publikováno v: Acta crystallographica. Section D, Biological crystallography [Acta Crystallogr D Biol Crystallogr] 2015 Apr; Vol. 71 (Pt 4), pp. 862-72. Date of Electronic Publication: 2015 Mar 26.

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Corrigendum: Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis.

Autor: Evans GL, Gamage SA, Bulloch EM, Baker EN, Denny WA, Lott JS

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2015 Mar 23; Vol. 16 (5), pp. 706. Date of Electronic Publication: 2015 Mar 11.

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Akademický článek

Identifying protein domains by global analysis of soluble fragment data.

Autor: Bulloch EM; School of Biological Sciences, University of Auckland, New Zealand. Electronic address: e.bulloch@auckland.ac.nz., Kingston RL; School of Biological Sciences, University of Auckland, New Zealand.

Publikováno v: Analytical biochemistry [Anal Biochem] 2014 Nov 15; Vol. 465, pp. 53-62. Date of Electronic Publication: 2014 Jul 10.

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Akademický článek

Transient dimerization of human MxA promotes GTP hydrolysis, resulting in a mechanical power stroke.

Autor: Rennie ML; Maurice Wilkins Centre, School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand., McKelvie SA; Maurice Wilkins Centre, School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand., Bulloch EM; Maurice Wilkins Centre, School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand., Kingston RL; Maurice Wilkins Centre, School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand. Electronic address: rl.kingston@auckland.ac.nz.

Publikováno v: Structure (London, England : 1993) [Structure] 2014 Oct 07; Vol. 22 (10), pp. 1433-45.

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Akademický článek

Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.

Autor: Cookson TV; Maurice Wilkins Centre for Molecular Biodiscovery, Biomolecular Interaction Centre and Department of Chemistry, University of Canterbury, 20 Kirkwood Avenue, Christchurch 8140, New Zealand., Castell A; †Maurice Wilkins Centre for Molecular Biodiscovery and School of Biological Sciences, University of Auckland, 3 Symonds Street, Auckland 1142, New Zealand., Bulloch EM; †Maurice Wilkins Centre for Molecular Biodiscovery and School of Biological Sciences, University of Auckland, 3 Symonds Street, Auckland 1142, New Zealand., Evans GL; †Maurice Wilkins Centre for Molecular Biodiscovery and School of Biological Sciences, University of Auckland, 3 Symonds Street, Auckland 1142, New Zealand., Short FL; †Maurice Wilkins Centre for Molecular Biodiscovery and School of Biological Sciences, University of Auckland, 3 Symonds Street, Auckland 1142, New Zealand., Baker EN; †Maurice Wilkins Centre for Molecular Biodiscovery and School of Biological Sciences, University of Auckland, 3 Symonds Street, Auckland 1142, New Zealand., Lott JS; †Maurice Wilkins Centre for Molecular Biodiscovery and School of Biological Sciences, University of Auckland, 3 Symonds Street, Auckland 1142, New Zealand., Parker EJ; Maurice Wilkins Centre for Molecular Biodiscovery, Biomolecular Interaction Centre and Department of Chemistry, University of Canterbury, 20 Kirkwood Avenue, Christchurch 8140, New Zealand.

Publikováno v: The Biochemical journal [Biochem J] 2014 Jul 01; Vol. 461 (1), pp. 87-98.

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Akademický článek

Repurposing the chemical scaffold of the anti-arthritic drug Lobenzarit to target tryptophan biosynthesis in Mycobacterium tuberculosis.

Autor: Evans GL; School of Biological Sciences, Faculty of Science, University of Auckland, Private Bag 92019, Auckland, 1142 (New Zealand). g.evans@auckland.ac.nz., Gamage SA, Bulloch EM, Baker EN, Denny WA, Lott JS

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2014 Apr 14; Vol. 15 (6), pp. 852-64. Date of Electronic Publication: 2014 Mar 12.

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