CHEX-seq detects single-cell genomic single-stranded DNA with catalytical potential.

Autor: Lu Y; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Lee J; Department of Systems Pharmacology and Translational Therapeutics Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Li J; Department of Systems Pharmacology and Translational Therapeutics Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Allu SR; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Wang J; Department of Systems Pharmacology and Translational Therapeutics Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Kim H; Department of Systems Pharmacology and Translational Therapeutics Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Bullaughey KL; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Fisher SA; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Nordgren CE; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Rosario JG; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Anderson SA; Department of Psychiatry, Children's Hospital of Philadelphia, ARC 517, 3615 Civic Center Blvd, Philadelphia, PA, 19104, USA., Ulyanova AV; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Brem S; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Chen HI; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Wolf JA; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Grady MS; Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Vinogradov SA; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Kim J; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, 19104, USA., Eberwine J; Department of Systems Pharmacology and Translational Therapeutics Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. eberwine@pennmedicine.upenn.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Nov 14; Vol. 14 (1), pp. 7346. Date of Electronic Publication: 2023 Nov 14.