Coagulation factor XI in cirrhosis does not predict thrombo-hemorrhagic complications and hepatic decompensation.

Autor: Zanetto A; Gastroenterology and Multivisceral Transplant Unit, Department of Surgery, Oncology and Gastroenterology, Padova University Hospital, Padova, Italy., Campello E; First Chair of Internal Medicine, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy; Thrombotic and Haemorrhagic Disease Unit, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy., Spiezia L; First Chair of Internal Medicine, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy; Thrombotic and Haemorrhagic Disease Unit, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy., Gavasso S; Thrombotic and Haemorrhagic Disease Unit, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy., Bulato C; Thrombotic and Haemorrhagic Disease Unit, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy., Burra P; Gastroenterology and Multivisceral Transplant Unit, Department of Surgery, Oncology and Gastroenterology, Padova University Hospital, Padova, Italy., Russo FP; Gastroenterology and Multivisceral Transplant Unit, Department of Surgery, Oncology and Gastroenterology, Padova University Hospital, Padova, Italy., Senzolo M; Gastroenterology and Multivisceral Transplant Unit, Department of Surgery, Oncology and Gastroenterology, Padova University Hospital, Padova, Italy., Simioni P; First Chair of Internal Medicine, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy; Thrombotic and Haemorrhagic Disease Unit, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy. Electronic address: paolo.simioni@unipd.it.

Publikováno v: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver [Dig Liver Dis] 2024 Jun 03. Date of Electronic Publication: 2024 Jun 03.

In vitro and ex vivo rescue of a nonsense mutation responsible for severe coagulation factor V deficiency.

Autor: Todaro AM; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands., Radu CM; Department of Medicine, Thrombotic and Haemorrhagic Diseases Unit, Padua University Medical School, Padua, Italy., Ciccone M; Department of Medical Sciences, Section of Haematology, Sant'Anna Hospital, Ferrara University, Ferrara, Italy., Toffanin S; Department of Medicine, Thrombotic and Haemorrhagic Diseases Unit, Padua University Medical School, Padua, Italy., Serino ML; Department of Medical Sciences, Section of Haematology, Sant'Anna Hospital, Ferrara University, Ferrara, Italy., Campello E; Department of Medicine, Thrombotic and Haemorrhagic Diseases Unit, Padua University Medical School, Padua, Italy., Bulato C; Department of Medicine, Thrombotic and Haemorrhagic Diseases Unit, Padua University Medical School, Padua, Italy., Lunghi B; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, Ferrara University, Ferrara, Italy., Gemmati D; Department of Translational Medicine, Haemostasis & Thrombosis Centre, Ferrara University, Ferrara, Italy., Cuneo A; Department of Medical Sciences, Section of Haematology, Sant'Anna Hospital, Ferrara University, Ferrara, Italy., Hackeng TM; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands., Simioni P; Department of Medicine, Thrombotic and Haemorrhagic Diseases Unit, Padua University Medical School, Padua, Italy., Bernardi F; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, Ferrara University, Ferrara, Italy., Castoldi E; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands. Electronic address: e.castoldi@maastrichtuniversity.nl.

Publikováno v: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2024 Feb; Vol. 22 (2), pp. 410-422. Date of Electronic Publication: 2023 Oct 21.

“In vitro” correction of the severe factor V deficiency‐related coagulopathy by a novel plasma‐derived factor V concentrate.

Autor: Bulato, C.¹, Novembrino, C.², Anzoletti, M. Boscolo², Spiezia, L.¹, Gavasso, S.¹, Berbenni, C.², Tagariello, G.³, Farina, C.⁴, Nardini, I.⁴, Campello, E.¹, Peyvandi, F.², Simioni, P.¹ paolo.simioni@unipd.it

Publikováno v: Haemophilia. Jul2018, Vol. 24 Issue 4, p648-656. 9p. 3 Charts, 3 Graphs.

Genetic modulation of the FVLeiden/normal FV ratio and risk of venous thrombosis in factor V Leiden heterozygotes

Autor: SEGERS, O., SIMIONI, P., TORMENE, D., BULATO, C., GAVASSO, S., ROSING, J., CASTOLDI, E. ^*

Publikováno v: In Journal of Thrombosis and Haemostasis January 2012 10(1):73-80

Severity of systemic inflammation is the main predictor of ACLF and bleeding in individuals with acutely decompensated cirrhosis.

Autor: Zanetto A; Gastroenterology and Multivisceral Transplant Unit, Azienda Ospedale - Università Padova, Padova, Italy; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Pelizzaro F; Gastroenterology and Multivisceral Transplant Unit, Azienda Ospedale - Università Padova, Padova, Italy; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Campello E; General Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Padova, Italy., Bulato C; General Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Padova, Italy., Balcar L; Vienna Hepatic Hemodynamic Lab, Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria., Gu W; Department of Internal Medicine I, Goethe University, Frankfurt, Germany; Department of Internal Medicine B, University Clinic Münster and Westfalen Wilhelms University, Münster, Germany., Gavasso S; General Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Padova, Italy., Saggiorato G; General Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Padova, Italy., Zeuzem S; Department of Internal Medicine I, Goethe University, Frankfurt, Germany., Russo FP; Gastroenterology and Multivisceral Transplant Unit, Azienda Ospedale - Università Padova, Padova, Italy; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Mandorfer M; Vienna Hepatic Hemodynamic Lab, Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria., Reiberger T; Vienna Hepatic Hemodynamic Lab, Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria., Trebicka J; Department of Internal Medicine I, Goethe University, Frankfurt, Germany; Department of Internal Medicine B, University Clinic Münster and Westfalen Wilhelms University, Münster, Germany; European Foundation for Study of Chronic Liver Failure (EF-Clif), Barcelona, Spain., Burra P; Gastroenterology and Multivisceral Transplant Unit, Azienda Ospedale - Università Padova, Padova, Italy; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Simioni P; General Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Padova, Italy. Electronic address: paolo.simioni@unipd.it., Senzolo M; Gastroenterology and Multivisceral Transplant Unit, Azienda Ospedale - Università Padova, Padova, Italy; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy. Electronic address: marcosenzolo@hotmail.com.

Publikováno v: Journal of hepatology [J Hepatol] 2023 Feb; Vol. 78 (2), pp. 301-311. Date of Electronic Publication: 2022 Sep 21.