Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bula, Bhattacharyya"'
Autor:
Rachel E, Miller, Shingo, Ishihara, Bula, Bhattacharyya, Ada, Delaney, Daniela M, Menichella, Richard J, Miller, Anne-Marie, Malfait
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 69(7)
To determine the ability of drugs that activate inhibitory G protein-coupled receptors (GPCRs) expressed in peripheral voltage-gated sodium channel 1.8 (NaWe used designer receptors exclusively activated by a designer drug (DREADD) technology, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f530c54b852f1e0e110822addbf0513
https://pubmed.ncbi.nlm.nih.gov/28435151
https://pubmed.ncbi.nlm.nih.gov/28435151
Publikováno v:
Anesthesia and analgesia. 81(4)
The mechanisms contributing to the neuromuscular block produced by nondepolarizing muscle relaxants and inhaled anesthetics include: 1) receptor blockade, 2) open or closed ion channel block, 3) decreased transmitter release, and 4) receptor desensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37427f514c656cc6e3016b3db401eed0
https://pubmed.ncbi.nlm.nih.gov/7574007
https://pubmed.ncbi.nlm.nih.gov/7574007
Publikováno v:
European journal of pharmacology. 195(1)
DOI (1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane) significantly depressed end plate current (EPC) amplitude. It decreased quantum content, increased the extent of neurally evoked EPC rundown during the train, produced a nonlinear current-voltage re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8012f8d885553a6c53646cd10b64db
https://pubmed.ncbi.nlm.nih.gov/1648493
https://pubmed.ncbi.nlm.nih.gov/1648493
Publikováno v:
European Journal of Pharmacology. 173:27-34
The effects of halothane and isoflurane on the acetylcholine activated ion channel were studied in the frog sartorius muscle using the two electrode voltage clamp technique. The miniature end-plate currents (MEPCs) were recorded and evaluated for amp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb00db8341cb505fa9d09d28835b2336
https://doi.org/10.1016/0014-2999(89)90005-8
https://doi.org/10.1016/0014-2999(89)90005-8
Publikováno v:
Biochemical Pharmacology. 32:2965-2968
Chloroquine (1, 5 and 10 mg/kg), given in acute and in chronic (7 and 15 days) treatment schedules, caused characteristic alterations in the lysosomal enzyme system, antioxidant enzymes, NADPH-induced lipid peroxidation, and glutathione content in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd7a4ec52d1c9fa4dc4b7aa0149b977
https://doi.org/10.1016/0006-2952(83)90403-3
https://doi.org/10.1016/0006-2952(83)90403-3
Autor:
Ranbir K. Bhatnagar, Alfred M. Nyanda, Joseph G. Cannon, Jan R. Flynn, Y.-a. Chang, Teresa M.-L. Lee, Bula Bhattacharyya, John P. Long, Tapan K. Chatterjee
Publikováno v:
Pharmaceutical Research. :359-364
In a continuing investigation of structural requirements for hemicholinium-like activity (inhibition of neuromuscular transmission due to inhibition of uptake of choline into nerve terminals), some additional molecular modifications of hemicholinium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5f45fcd9b92e07399e8f387f5f49a37
https://doi.org/10.1023/a:1015955527100
https://doi.org/10.1023/a:1015955527100
Autor:
Joe G. Cannon, Bula Bhattacharyya, John P. Long, Peggy Bhalla, Delores Reed, Clark E. Tedford
Publikováno v:
European journal of pharmacology. 128(3)
A series of substituted piperidine analogs of hemicholinium-3 was evaluated for their ability to inhibit neuromuscular transmission, to decrease acetylcholine content of caudate slices, to inhibit choline acetyltransferase activity, and to produce to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8344b677b2bb4cebff80cda02561c3b5
https://pubmed.ncbi.nlm.nih.gov/3024994
https://pubmed.ncbi.nlm.nih.gov/3024994
Publikováno v:
European journal of pharmacology. 146(1)
Two hemicholinium-3 (HC-3) analogs (NAM-204 and NAM-224) in which the C=O moiety was reduced to −CH2 and 2- or 3-CH3 substitution on the piperidine ring were demonstrated to produce a different type of neuromuscular inhibition than that induced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b7df97e92d1a1fb39988f5bc475e5f
https://pubmed.ncbi.nlm.nih.gov/2832194
https://pubmed.ncbi.nlm.nih.gov/2832194
Publikováno v:
European journal of pharmacology. 132(2-3)
Piperidine derivatives of hemicholinium-3 were synthesized and included the following spacing groups between the bis-cationic heads: trans,trans-bicyclohexyl, phenanthrene, naphthalene and biphenyl. Anticholinesterase activity was determined using ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4328fc9a432942c9eed4580d68163ce9
https://pubmed.ncbi.nlm.nih.gov/3028835
https://pubmed.ncbi.nlm.nih.gov/3028835