Zobrazeno 1 - 10
of 3 777
pro vyhledávání: '"Bukreyev A"'
Autor:
Ivan V. Kuzmin, Ruben Soto Acosta, Layne Pruitt, Perry T. Wasdin, Kritika Kedarinath, Keziah R. Hernandez, Kristyn A. Gonzales, Kharighan Hill, Nicole G. Weidner, Chad Mire, Taylor B. Engdahl, Woohyun J. Moon, Vsevolod Popov, James E. Crowe, Ivelin S. Georgiev, Mariano A. Garcia-Blanco, Robert K. Abbott, Alexander Bukreyev
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The rodent-borne Andes virus (ANDV) causes a severe disease in humans. We developed an ANDV mRNA vaccine based on the M segment of the viral genome, either with regular uridine (U-mRNA) or N1-methylpseudouridine (m1Ψ-mRNA). Female mice immu
Externí odkaz:
https://doaj.org/article/b9d9f5258a8943afbcc90d9e051b9c63
Autor:
Philipp A. Ilinykh, Kai Huang, Bronwyn M. Gunn, Natalia A. Kuzmina, Kritika Kedarinath, Eduardo Jurado-Cobena, Fuchun Zhou, Chandru Subramani, Matthew A. Hyde, Jalene V. Velazquez, Lauren E. Williamson, Pavlo Gilchuk, Robert H. Carnahan, Galit Alter, James E. Crowe, Alexander Bukreyev
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Antibodies to Ebola virus glycoprotein (EBOV GP) represent an important correlate of the vaccine efficiency and infection survival. Both neutralization and some of the Fc-mediated effects are known to contribute the protection conferred by a
Externí odkaz:
https://doaj.org/article/446ca9702148453eb38e081a5253376d
Autor:
Rodrigo I. Santos, Alexander Bukreyev
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103363- (2024)
Summary: Previous work demonstrates that ebolaviruses can spread to neighboring cells through intercellular connections. Here, we present a protocol to quantify the intercellular spread of ebolaviruses via immunofluorescence. We describe steps for ce
Externí odkaz:
https://doaj.org/article/c25b044520a441e3997453ea720344af
Autor:
Adam J. Ronk, Nicole M. Lloyd, Min Zhang, Caroline Atyeo, Hailee R. Perrett, Chad E. Mire, Kathryn M. Hastie, Rogier W. Sanders, Philip J. M. Brouwer, Erica Olmann Saphire, Andrew B. Ward, Thomas G. Ksiazek, Juan Carlos Alvarez Moreno, Harshwardhan M. Thaker, Galit Alter, Sunny Himansu, Andrea Carfi, Alexander Bukreyev
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Lassa virus is a member of the Arenaviridae family, which causes human infections ranging from asymptomatic to severe hemorrhagic disease with a high case fatality rate. We have designed and generated lipid nanoparticle encapsulated, modifie
Externí odkaz:
https://doaj.org/article/4afd193033d54672afc7fc5b00f7b333
Autor:
Philipp A. Ilinykh, Kai Huang, Bronwyn M. Gunn, Natalia A. Kuzmina, Kritika Kedarinath, Eduardo Jurado-Cobena, Fuchun Zhou, Chandru Subramani, Matthew A. Hyde, Jalene V. Velazquez, Lauren E. Williamson, Pavlo Gilchuk, Robert H. Carnahan, Galit Alter, James E. Crowe, Alexander Bukreyev
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/363dea2b3f8140e3a227009c6ff258aa
Autor:
Santos, Rodrigo I., Ilinykh, Philipp A., Pietzsch, Colette A., Ronk, Adam J., Huang, Kai, Kuzmina, Natalia A., Zhou, Fuchun, Crowe, James E., Bukreyev, Alexander
Publikováno v:
In Cell Reports 31 October 2023 42(10)
Autor:
Ilinykh PA; Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.; Galveston National Laboratory, Galveston, TX, USA., Huang K; Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.; Galveston National Laboratory, Galveston, TX, USA., Gunn BM; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Kuzmina NA; Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.; Galveston National Laboratory, Galveston, TX, USA., Kedarinath K; Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.; Galveston National Laboratory, Galveston, TX, USA., Jurado-Cobena E; Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.; Galveston National Laboratory, Galveston, TX, USA., Zhou F; Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.; Galveston National Laboratory, Galveston, TX, USA., Subramani C; Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.; Galveston National Laboratory, Galveston, TX, USA., Hyde MA; Galveston National Laboratory, Galveston, TX, USA., Velazquez JV; Paul G. Allen School of Global Health, Washington State University, Pullman, WA, USA., Williamson LE; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, USA., Gilchuk P; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, USA., Carnahan RH; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA., Alter G; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA. Galit.Alter@modernatx.com., Crowe JE Jr; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, USA. james.crowe@vumc.org.; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA. james.crowe@vumc.org.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA. james.crowe@vumc.org., Bukreyev A; Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA. alexander.bukreyev@utmb.edu.; Galveston National Laboratory, Galveston, TX, USA. alexander.bukreyev@utmb.edu.; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA. alexander.bukreyev@utmb.edu.
Publikováno v:
Communications biology [Commun Biol] 2024 Jul 17; Vol. 7 (1), pp. 871. Date of Electronic Publication: 2024 Jul 17.
Autor:
Rodrigo I. Santos, Philipp A. Ilinykh, Colette A. Pietzsch, Adam J. Ronk, Kai Huang, Natalia A. Kuzmina, Fuchun Zhou, James E. Crowe, Alexander Bukreyev
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113254- (2023)
Summary: Ebola virus (EBOV) and Bundibugyo virus (BDBV) belong to the family Filoviridae and cause a severe disease in humans. We previously isolated a large panel of monoclonal antibodies from B cells of human survivors from the 2007 Uganda BDBV out
Externí odkaz:
https://doaj.org/article/8a1292785f724a3abef3fab20ae45612
Autor:
Shixia Wang, Chang Yi Wang, Hui-Kai Kuo, Wen-Jiun Peng, Juin-Hua Huang, Be-Shen Kuo, Feng Lin, Yaw-Jen Liu, Zhi Liu, Huang-Ting Wu, Shuang Ding, Kou-Liang Hou, Jennifer Cheng, Ya-Ting Yang, Ming-Han Jiang, Min-Sheng Wang, Tony Chen, Wei Guo Xia, Ed Lin, Chung Ho Hung, Hui-Jung Chen, Zhonghao Shih, Yi Ling Lin, Valorie Ryan, Mei Mei Hu, D. Gray Heppner, Delphine C. Malherbe, Sivakumar Periasamy, Natalia Kuzmina, Chandru Subramani, Michael Hellerstein, Thomas P. Monath, Alexander Rumyantsev, Alexander Bukreyev, Farshad Guirakhoo
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2724-2734 (2022)
The development of safe and effective vaccines to respond to COVID-19 pandemic/endemic remains a priority. We developed a novel subunit protein-peptide COVID-19 vaccine candidate (UB-612) composed of: (i) receptor binding domain of SARS-CoV-2 spike p
Externí odkaz:
https://doaj.org/article/d9e5af23b5ef47048009e734003b47bf