Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Buket Aydas"'
Publikováno v:
Cancer Medicine, Vol 12, Iss 19, Pp 19644-19655 (2023)
Abstract Background Pancreatic cancer (PC) is among the most lethal cancers. The lack of effective tools for early detection results in late tumor detection and, consequently, high mortality rate. Precision oncology aims to develop targeted individua
Externí odkaz:
https://doaj.org/article/cce1f63bf4134a7ebff1e6f9e5c7e6dd
Autor:
Ray O. Bahado-Singh, Amin Ibrahim, Zaid Al-Wahab, Buket Aydas, Uppala Radhakrishna, Ali Yilmaz, Sangeetha Vishweswaraiah
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Ovarian cancer (OC) is the most lethal gynecologic cancer due primarily to its asymptomatic nature and late stage at diagnosis. The development of non-invasive markers is an urgent priority. We report the accurate detection of epithelial OC
Externí odkaz:
https://doaj.org/article/bb696cacbf2445b293e29499c0c4fa77
Autor:
Ray Bahado-Singh, Kyriacos T. Vlachos, Buket Aydas, Juozas Gordevicius, Uppala Radhakrishna, Sangeetha Vishweswaraiah
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundLung cancer (LC) is a leading cause of cancer-deaths globally. Its lethality is due in large part to the paucity of accurate screening markers. Precision Medicine includes the use of omics technology and novel analytic approaches for biomar
Externí odkaz:
https://doaj.org/article/d758b84d3845486c8fdadd8bbd74a1cf
Autor:
Ray O Bahado-Singh, Sangeetha Vishweswaraiah, Buket Aydas, Ali Yilmaz, Raghu P Metpally, David J Carey, Richard C Crist, Wade H Berrettini, George D Wilson, Khalid Imam, Michael Maddens, Halil Bisgin, Stewart F Graham, Uppala Radhakrishna
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248375 (2021)
We evaluated the utility of leucocyte epigenomic-biomarkers for Alzheimer's Disease (AD) detection and elucidates its molecular pathogeneses. Genome-wide DNA methylation analysis was performed using the Infinium MethylationEPIC BeadChip array in 24 l
Externí odkaz:
https://doaj.org/article/d9537ca420cb4d748465ee176c2f4948
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253340 (2021)
Autism spectrum disorder (ASD) is associated with abnormal brain development during fetal life. Overall, increasing evidence indicates an important role of epigenetic dysfunction in ASD. The placenta is critical to and produces neurotransmitters that
Externí odkaz:
https://doaj.org/article/5664f392ed594656b803784aa3ab2aa2
Autor:
Ray O. Bahado-Singh, Uppala Radhakrishna, Juozas Gordevičius, Buket Aydas, Ali Yilmaz, Faryal Jafar, Khaled Imam, Michael Maddens, Kshetra Challapalli, Raghu P. Metpally, Wade H. Berrettini, Richard C. Crist, Stewart F. Graham, Sangeetha Vishweswaraiah
Publikováno v:
Cells, Vol 11, Iss 11, p 1744 (2022)
Background: Despite extensive efforts, significant gaps remain in our understanding of Alzheimer’s disease (AD) pathophysiology. Novel approaches using circulating cell-free DNA (cfDNA) have the potential to revolutionize our understanding of neuro
Externí odkaz:
https://doaj.org/article/26aa0b56552f485dae0c87a376ca3611
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0209725 (2020)
This paper describes CarbMetSim, a discrete-event simulator that tracks the blood glucose level of a person in response to a timed sequence of diet and exercise activities. CarbMetSim implements broader aspects of carbohydrate metabolism in human bei
Externí odkaz:
https://doaj.org/article/c06bd89d63b842cf854525060d93438f
Autor:
Zeynep Alpay Savasan, Ali Yilmaz, Zafer Ugur, Buket Aydas, Ray O. Bahado-Singh, Stewart F. Graham
Publikováno v:
Metabolites, Vol 9, Iss 2, p 27 (2019)
Cerebral palsy (CP) is one of the most common causes of motor disability in childhood, with complex and heterogeneous etiopathophysiology and clinical presentation. Understanding the metabolic processes associated with the disease may aid in the disc
Externí odkaz:
https://doaj.org/article/80f0b93e68fc4eb8bd6086cf354569d2
Publikováno v:
Journal of the Operational Research Society. 74:310-329
Publikováno v:
The Journal of Maternal-Fetal & Neonatal Medicine. 35:8150-8159
Autism Spectrum Disorder (ASD) represents a heterogeneous group of disorders with a complex genetic and epigenomic etiology. DNA methylation is the most extensively studied epigenomic mechanism and correlates with altered gene expression. Artificial