Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Buket ALPERTUNGA"'
Autor:
Ayse Tarbin Jannuzzi, Sema Arslan, Ayse Mine Yilmaz, Gulce Sari, Hande Beklen, Lucía Méndez, Maria Fedorova, Kazim Yalcin Arga, Betul Karademir Yilmaz, Buket Alpertunga
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Proteasome inhibitors have great success for their therapeutic potential against hematologic malignancies. First generation proteasome inhibitor bortezomib induced peripheral neuropathy is considered as a limiting factor in chemotherapy and its secon
Externí odkaz:
https://doaj.org/article/a94b4a478a434fd591596f7f25ad6a08
Publikováno v:
Proceedings, Vol 2, Iss 25, p 1583 (2018)
The ubiquitin proteasomal system and autophagic pathway are two main protein degradation systems in eukaryotic cells. Inhibition of the proteasomal system with proteasome inhibitors for cancer treatment can cause neurotoxic side effects. In this stud
Externí odkaz:
https://doaj.org/article/dd4f8ee42cd84cd78f1c634db5e75796
Publikováno v:
Mediators of Inflammation, Vol 2010 (2010)
Proinflammatory cytokines, such as tumour necrosis factor α (TNFα), play fundamental roles in the pathogenesis of acute pancreatitis (AP). The aim of this study was to determine if polymorphisms in the TNFα gene are associated with AP. Two polymor
Externí odkaz:
https://doaj.org/article/9a9ddac536ed495e8e0fcade347ca54d
Publikováno v:
Toxicol Res (Camb)
Background: JWH-018 was the first synthetic cannabinoid introduced as a legal high and the first of the new generation of novel psychoactive substances that flooded worldwide drug markets. JWH-018 was marketed as “spice,” “herbal incense,” or
Publikováno v:
Turk J Pharm Sci
OBJECTIVES: Tattooing is an ancient practice and its popularity has been increasing in the recent years. After tattooing, complications may occur related to compose tattoo inks. In this study, the phototoxicity potential of the blue, red and black co
Publikováno v:
Environmental Toxicology and Pharmacology. 96:104005
© 2022 Elsevier B.V.The consumption of the widely used flame retardant Triphenyl phosphate (TPP) is increasing. It is now frequently detected in the environment and also domestically. Although the possibility of dermal exposure to TPP is quite high,
Publikováno v:
Toxicology and applied pharmacology. 423
Lenvatinib is a tyrosine kinase inhibitor (TKI) approved for the treatment of resistant differentiated thyroid cancer, advanced renal cell carcinoma, unresectable hepatocellular carcinoma, and endometrial carcinoma. Although it is successful in cance
Publikováno v:
Toxicology letters. 336
Regorafenib (RGF) has a great success in the treatment of colorectal cancer, gastrointestinal stromal tumours and hepatocellular carcinoma by inhibiting angiogenic, stromal and oncogenic kinases. However, RGF can induce life-threatening cardiotoxicit
Publikováno v:
Steroids. 134:96-100
Stanozolol is a widely used 17α-alkylated anabolic androgenic steroid (AAS) derivative. Despite stanozolol’s adverse effects, its effect on oxidative stress parameters and mitochondrial apoptosis pathway is not clearly defined. In our study, thirt
Autor:
Mehtap Kara, Aristides M. Tsatsakis, Eren Ozcagli, Polychronis Stivaktakis, Tuğba Kotil, Persefoni Fragkiadaki, Dimitrios Tsoukalas, Christina Tsitsimpikou, Manolis Tzatzarakis, Demetrios A. Spandidos, Buket Alpertunga
Publikováno v:
International Journal of Molecular Medicine
Anabolic agents are doping substances which are commonly used in sports. Stanozolol, a 17α-alkylated derivative of testosterone, has a widespread use among athletes and bodybuilders. Several medical and behavioral adverse effects are associated with