Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Bujun Ge"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
mRNA delivery has shown great potential in the treatment of various diseases. Here, the authors develop a lantern-shaped flexible origami for nanolization of single mRNA molecules and demonstrate efficient delivery of Smad4 mRNA, achieving suppressio
Externí odkaz:
https://doaj.org/article/faa2c676bcc14678867284465c00044b
Autor:
Zhizhan Ni, Yuepeng Cao, Liming Liu, Chenshen Huang, Huahao Xie, Jinzhe Zhou, Bujun Ge, Qi Huang
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-7 (2023)
Abstract Background Self-expanding metal stents (SEMS) served as a bridge to surgery (BTS). However, this method may be associated with worse long-term prognosis and relapse of CRC patients. Therefore, we attempted to clarify this in the angle of cir
Externí odkaz:
https://doaj.org/article/1f1a83177a0f41ff81fbed8b0a434190
Autor:
Chenshen Huang, Ning Wang, Na Zhang, Zhizhong Chen, Zhizhan Ni, Xiaohong Liu, Hao Xiong, Huahao Xie, Boxu Lin, Bujun Ge, Qi Huang, Bing Du
Publikováno v:
Open Biology, Vol 12, Iss 8 (2022)
Accumulating evidence suggests that inflammation-related genes may play key roles in tumour immune evasion. Programmed cell death ligand 1 (PD-L1) is an important immune checkpoint involved in mediating anti-tumour immunity. We performed multi-omics
Externí odkaz:
https://doaj.org/article/3d683fec8513440baf8152adff1ebcfd
Autor:
Yuepeng Cao, Qing Chen, Zhizhan Ni, Feng Wu, Chenshen Huang, Jinzhe Zhou, Songze Zhang, Bujun Ge, Qi Huang
Publikováno v:
BMC Surgery, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Bridge to elective surgery (BTS) using self-expanding metal stents (SEMSs) is a common alternative to emergency surgery (ES) for acute malignant left-sided colonic obstruction (AMLCO). However, studies regarding the long-term impa
Externí odkaz:
https://doaj.org/article/b8062b4351c8443489b045a93e49cf6d
Autor:
Chenshen Huang, Na Zhang, Hao Xiong, Ning Wang, Zhizhong Chen, Zhizhan Ni, Xiaohong Liu, Boxu Lin, Bujun Ge, Bing Du, Qi Huang
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
BackgroundCurrently, a comprehensive method for exploration of transcriptional regulation has not been well established. We explored a novel pipeline to analyze transcriptional regulation using co-analysis of RNA sequencing (RNA-seq), assay for trans
Externí odkaz:
https://doaj.org/article/453b971e0a954fc3bffe337246c93308
Publikováno v:
Frontiers in Surgery, Vol 8 (2021)
Background: Because of the challenge of jejunal closure recanalization, uncut Roux-en-Y reconstruction remains controversial. This study aimed to investigate the incidence of recanalization after uncut Roux-en-Y reconstruction in pigs and a small num
Externí odkaz:
https://doaj.org/article/43d73d4a7118430098be89aab572daa8
Autor:
Zhizhan Ni, Chenshen Huang, Hongmei Zhao, Jinzhe Zhou, Muren Hu, Qing Chen, Bujun Ge, Qi Huang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
BackgroundGastric cancer is associated with tumor microenvironment and chronic inflammation, but the underlying tumor-promoting mechanisms still remain unknown.MethodsThe ATAC-seq was used to identify genes with chromatin accessibilities in promoter
Externí odkaz:
https://doaj.org/article/3a962c13996d4574a9c27fbf768456c9
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
BackgroundWe explored key molecules affecting the prognosis of gastric adenocarcinoma (STAD) using co-analysis of chromatin accessibility (ATAC-seq), mRNA expression (RNA-seq), and overall survival.MethodsWe used the assay for transposase-accessible
Externí odkaz:
https://doaj.org/article/2209659e59d948879c77a098283e1d52
Autor:
Zhizhan Ni, Xin Chen, Qi Huang, Jinzhe Zhou, Huahao Xie, Song Wang, Jiebang Jiang, Liming Liu, Bujun Ge
Background: Tumor-associated macrophages(TAMs), especially M2 macrophages, plays a critical role in Colorectal cancer initiation, promotion, and metastasis. However, the underlying mechanisms still remain unresolved. Methods:The profile of ATAC-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b79f197a681c0b72955836647fc553b
https://doi.org/10.21203/rs.3.rs-2716212/v1
https://doi.org/10.21203/rs.3.rs-2716212/v1
Autor:
Huahao Xie, Feng Wu, Chenshen Huang, Quanning Chen, Zhizhan Ni, Song Wang, Bujun Ge, Liming Liu, Qi Huang
Publikováno v:
Journal of Gastrointestinal Surgery.
Background Traditional Roux-en-Y may cause Roux-en-Y stasis syndrome (RSS), and Uncut Roux-en-Y was proposed to solve this problem. However, because afferent loop recanalization may occur after surgery, its clinical application remains controversial.