USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.

Autor: Reissland M; Protein Stability and Cancer Group, University of Wuerzburg, Department of Biochemistry and Molecular Biology, Wuerzburg, Germany.; Mildred-Scheel Early Career Cancer Center, Wuerzburg, Germany.; Max Planck Institute for Molecular Genetics, Berlin, Germany., Hartmann O; Protein Stability and Cancer Group, University of Wuerzburg, Department of Biochemistry and Molecular Biology, Wuerzburg, Germany.; Mildred-Scheel Early Career Cancer Center, Wuerzburg, Germany., Tauch S; Protein Stability and Cancer Group, University of Wuerzburg, Department of Biochemistry and Molecular Biology, Wuerzburg, Germany.; Division of Signal Transduction and Growth Control, DKFZ/ZMBH Alliance, German Cancer Research Center (DKFZ), Heidelberg, Germany., Bugter JM; Oncode Institute and Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, Netherlands., Prieto-Garcia C; Protein Stability and Cancer Group, University of Wuerzburg, Department of Biochemistry and Molecular Biology, Wuerzburg, Germany.; Molecular Signalling Group, Institute of Biochemistry II, Goethe University Frankfurt, Frankfurt am Main, Germany., Schulte C; Rudolf-Virchow-Center for Integrative and Translational Imaging, University of Wuerzburg, Wuerzburg, Germany., Loebbert S; Mildred-Scheel Early Career Cancer Center, Wuerzburg, Germany.; Department of Biochemistry and Molecular Biology, University of Wuerzburg, Wuerzburg, Germany., Solvie D; Department of Biochemistry and Molecular Biology, University of Wuerzburg, Wuerzburg, Germany., Bitman-Lotan E; Faculty of Medicine, TICC, Technion Haifa, Haifa, Israel., Narain A; Cancer Systems Biology Group, University of Wuerzburg, Am Hubland, Wuerzburg, Germany., Jacomin AC; Molecular Signalling Group, Institute of Biochemistry II, Goethe University Frankfurt, Frankfurt am Main, Germany., Schuelein-Voelk C; Department of Biochemistry and Molecular Biology, University of Wuerzburg, Wuerzburg, Germany., Fuss CT; Protein Stability and Cancer Group, University of Wuerzburg, Department of Biochemistry and Molecular Biology, Wuerzburg, Germany.; Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Wuerzburg, Wuerzburg, Germany., Pahor N; Protein Stability and Cancer Group, University of Wuerzburg, Department of Biochemistry and Molecular Biology, Wuerzburg, Germany.; Mildred-Scheel Early Career Cancer Center, Wuerzburg, Germany., Ade C; Department of Biochemistry and Molecular Biology, University of Wuerzburg, Wuerzburg, Germany., Buck V; Institute for Pathology, University of Würzburg, Wuerzburg, Germany., Potente M; Angiogenesis & Metabolism Laboratory, Berlin Institute of Health at Charité, Universitätsmedizin Berlin, Berlin Germany and Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany., Li V; Stem Cell and Cancer Biology Laboratory, The Francis Crick Institute, London, UK., Beliu G; Institute of Lung Health and Immunity, Helmholtz Center, Munich, Germany., Wiegering A; Department of Biochemistry and Molecular Biology, University of Wuerzburg, Wuerzburg, Germany.; Department of General, Visceral, Transplantation, Vascular and Paediatric Surgery, University Hospital, Julius-Maximilians-University of Wuerzburg, Wuerzburg, Germany., Grossmann T; Amsterdam Institute of Molecular and Life Sciences, Amsterdam, Netherlands., Eilers M; Mildred-Scheel Early Career Cancer Center, Wuerzburg, Germany.; Department of Biochemistry and Molecular Biology, University of Wuerzburg, Wuerzburg, Germany., Wolf E; Mildred-Scheel Early Career Cancer Center, Wuerzburg, Germany.; Cancer Systems Biology Group, University of Wuerzburg, Am Hubland, Wuerzburg, Germany., Maric H; Rudolf-Virchow-Center for Integrative and Translational Imaging, University of Wuerzburg, Wuerzburg, Germany., Rosenfeldt M; Mildred-Scheel Early Career Cancer Center, Wuerzburg, Germany.; Institute for Pathology, University of Würzburg, Wuerzburg, Germany., Maurice MM; Oncode Institute and Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, Netherlands., Dikic I; Molecular Signalling Group, Institute of Biochemistry II, Goethe University Frankfurt, Frankfurt am Main, Germany., Gallant P; Department of Biochemistry and Molecular Biology, University of Wuerzburg, Wuerzburg, Germany., Orian A; Faculty of Medicine, TICC, Technion Haifa, Haifa, Israel., Diefenbacher ME; Protein Stability and Cancer Group, University of Wuerzburg, Department of Biochemistry and Molecular Biology, Wuerzburg, Germany. markus.diefenbacher@helmholtz-munich.de.; Mildred-Scheel Early Career Cancer Center, Wuerzburg, Germany. markus.diefenbacher@helmholtz-munich.de.; Institute of Lung Health and Immunity, Helmholtz Center, Munich, Germany. markus.diefenbacher@helmholtz-munich.de.; German Center for Lung Research, DZL, Germany. markus.diefenbacher@helmholtz-munich.de.; Ludwig Maximilian University Munich, Munich, Germany. markus.diefenbacher@helmholtz-munich.de.

Publikováno v: Oncogene [Oncogene] 2024 Dec; Vol. 43 (50), pp. 3645-3659. Date of Electronic Publication: 2024 Oct 23.

Publisher Correction: Mutations and mechanisms of WNT pathway tumour suppressors in cancer.

Autor: Bugter JM; Oncode Institute and Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, Netherlands., Fenderico N; Oncode Institute and Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, Netherlands., Maurice MM; Oncode Institute and Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, Netherlands. m.m.maurice@umcutrecht.nl.

Publikováno v: Nature reviews. Cancer [Nat Rev Cancer] 2021 Jan; Vol. 21 (1), pp. 64.

RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.

Autor: Spit M; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Fenderico N; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Jordens I; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Radaszkiewicz T; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic., Lindeboom RG; Department of Molecular Biology and Oncode Institute, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands., Bugter JM; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Cristobal A; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Ootes L; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., van Osch M; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Janssen E; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Boonekamp KE; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Hanakova K; Central European Institute of Technology, Masaryk University, Brno, Czech Republic., Potesil D; Central European Institute of Technology, Masaryk University, Brno, Czech Republic., Zdrahal Z; Central European Institute of Technology, Masaryk University, Brno, Czech Republic., Boj SF; Hubrecht Organoid Technology, Utrecht, The Netherlands., Medema JP; Laboratory for Experimental Oncology and Radiobiology and Oncode Institute, Center for Experimental and Molecular Medicine, Amsterdam UMC, Cancer Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands., Bryja V; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic., Koo BK; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria., Vermeulen M; Department of Molecular Biology and Oncode Institute, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands., Maurice MM; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.

Publikováno v: The EMBO journal [EMBO J] 2020 Sep 15; Vol. 39 (18), pp. e103932. Date of Electronic Publication: 2020 Aug 10.