Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Bugreev DV"'
Publikováno v:
Molecular Biology. 39:862-875
Quantitative analysis was performed for the first time for the interaction of Escherichia coli RecA, which plays the central role in homologous recombination, and ssDNA varying in length and structure. DNA recognition was shown to depend on weak addi
Publikováno v:
FEBS Journal. 272:2734-2745
RecA protein plays a pivotal role in homologous recombination in Escherichia coli. RecA polymerizes on single-stranded (ss) DNA forming a nucleoprotein filament. Then double-stranded (ds) DNA is bound and searched for segments homologous to the ssDNA
Publikováno v:
Russian Journal of Bioorganic Chemistry. 29:249-261
Data on the interaction of DNA type I topoisomerases from the murine and human placenta cells with specific and nonspecific oligonucleotides of various structures and lengths are summarized. The relative contributions of various contacts between the
Publikováno v:
Russian Journal of Bioorganic Chemistry. 29:143-153
Interaction of the DNA type I topoisomerases from the murine and human placenta cells with nonspecific oligonucleotides was analyzed. The contributions of strong and week nonspecific electrostatic, van der Waals's, and hydrophobic interactions, and h
Publikováno v:
Molecular Biology. 37:281-292
Eukaryotic DNA topoisomerase I (Topo) regulates the topological state of cell DNA and plays an important part in replication, transcription, repair, and recombination. Factors affecting the specific recognition of topologically stressed DNA were anal
Autor:
Bugreev Dv, Georgy A. Nevinsky, Elena L. Vasyutina, Alexander N. Sinyakov, Valentina N. Buneva, Vladimir A. Ryabinin
Publikováno v:
Antisense and Nucleic Acid Drug Development. 11:137-147
A series of novel thiazole-containing oligopeptides (oligo-1,3-thiazolecarboxamides) interesting specifically with the minor groove of DNA was shown to inhibit human DNA topoisomerase I (topo I). Inhibitory effects of thiazole-containing oligopeptide
Publikováno v:
Russian Journal of Bioorganic Chemistry. 27:167-172
N9-Polymethylene derivatives of adenine and hypoxanthine with various functional groups in the ω-position of the alkyl substituent were synthesized. Their physicochemical properties and effect on the HIV reverse transcriptase and DNA topoisomerase I
Autor:
Valentina N. Buneva, Toshiwo Andoh, Bugreev Dv, Yoshihiro Yasui, Georgy A. Nevinsky, Miwako Nishizawa
Publikováno v:
FEBS Letters. 368:97-100
The interaction of DNA topoisomerase I (topo I) with a set of single- and double-stranded oligonucleotides containing 5–27 mononucleotides was investigated. All single- and double-stranded oligonucleotides were found to inhibit competitively the su
Autor:
T. Andoh, Bugreev Dv, Valentina N. Buneva, Tat'yana I. Kolocheva, G.A. Nevinsky, Elena L. Vasyutina
Publikováno v:
Biochimie. 80(4)
The interaction of human DNA topoisomerase I (topo I) with specific sequence oligodeoxynucleotides (ODNs) of different length and structure has been investigated. All the ODNs used were shown to be effective enzyme inhibitors and to inhibit the topo
Autor:
Bugreev Dv, Toshiwo Andoh, Miwako Nishizawa, Georgy A. Nevinsky, Valentina N. Buneva, Elena L. Vasyutina, Yoshihiro Yasui
Publikováno v:
FEBS letters. 407(1)
Recently mouse DNA topoisomerase I (topo) was shown to possess high affinity for a single-stranded AAGACTTAG nonanucleotide (K(i) = 2.0 microM) corresponding to the scissile strand of the minimal DNA duplex, which is necessary for cleavage of superco