Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Bugra, Ozer"'
Autor:
Saatviga Sudhahar, Bugra Ozer, Jiakang Chang, Wayne Chadwick, Daniel O’Donovan, Aoife Campbell, Emma Tulip, Neil Thompson, Ian Roberts
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Explaining predictions for drug repositioning with biological knowledge graphs is a challenging problem. Graph completion methods using symbolic reasoning predict drug treatments and associated rules to generate evidence representing the the
Externí odkaz:
https://doaj.org/article/a3a9e69ec3314471b6379af78138ae76
Autor:
Udai Banerji, Bissan Al-Lazikani, Johann de Bono, Florence Raynaud, Mary O'Brien, Sanjay Popat, Suzanne Carreira, Ruth Ruddle, Lisa Pickard, Anna Minchom, Bugra Ozer, Adam Stewart, Elizabeth A. Coker
Supplementary Table from Individualized Prediction of Drug Response and Rational Combination Therapy in NSCLC Using Artificial Intelligence–Enabled Studies of Acute Phosphoproteomic Changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e95cf42638e9a18caccef53889f34f
https://doi.org/10.1158/1535-7163.22521879.v1
https://doi.org/10.1158/1535-7163.22521879.v1
Autor:
Udai Banerji, Bissan Al-Lazikani, Johann de Bono, Florence Raynaud, Mary O'Brien, Sanjay Popat, Suzanne Carreira, Ruth Ruddle, Lisa Pickard, Anna Minchom, Bugra Ozer, Adam Stewart, Elizabeth A. Coker
We hypothesize that the study of acute protein perturbation in signal transduction by targeted anticancer drugs can predict drug sensitivity of these agents used as single agents and rational combination therapy. We assayed dynamic changes in 52 phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22528fb1aa4b1f2ee6b7d19fa1315474
https://doi.org/10.1158/1535-7163.c.6543207
https://doi.org/10.1158/1535-7163.c.6543207
Autor:
Bugra Ozer, Ugur Sezerman
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171694 (2017)
DNA methylation is an important epigenetic phenomenon that plays a key role in the regulation of expression. Most of the studies on the topic of methylation's role in cancer mechanisms include analyses based on differential methylation, with the inte
Externí odkaz:
https://doaj.org/article/92642c59ce9a402a8db083a0b44db321
Autor:
Rahul S. Samant, Silvia Batista, Mark Larance, Bugra Ozer, Christopher I. Milton, Isabell Bludau, Estelle Wu, Laura Biggins, Simon Andrews, Alexia Hervieu, Harvey E. Johnston, Bissan Al-Lazikhani, Angus I. Lamond, Paul A. Clarke, Paul Workman
Publikováno v:
Molecularcellular proteomics : MCP.
The molecular chaperone heat shock protein 90 (HSP90) works in concert with co-chaperones to stabilize its client proteins, which include multiple drivers of oncogenesis and malignant progression. Pharmacologic inhibitors of HSP90 have been observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0904af941dabe05cfa40fc268d8dd4e4
https://pubmed.ncbi.nlm.nih.gov/36549590
https://pubmed.ncbi.nlm.nih.gov/36549590
Autor:
Rahul S. Samant, Silvia Batista, Mark Larance, Bugra Ozer, Christopher I. Milton, Isabell Bludau, Laura Biggins, Simon Andrews, Alexia Hervieu, Harvey E. Johnston, Bissan Al-Lazikhani, Angus I. Lamond, Paul A. Clarke, Paul Workman
The molecular chaperone heat shock protein 90 (HSP90) works in concert with co-chaperones to stabilize its client proteins, which include multiple drivers of oncogenesis and malignant progression. Pharmacologic inhibitors of HSP90 have been observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b072aed1f9bd03dd78387065dbf1cad
https://doi.org/10.1101/2022.05.23.492985
https://doi.org/10.1101/2022.05.23.492985
Autor:
Costas Mitsopoulos, Patrizio Di Micco, Eloy Villasclaras Fernandez, Daniela Dolciami, Esty Holt, Ioan L Mica, Elizabeth A Coker, Joseph E Tym, James Campbell, Ka Hing Che, Bugra Ozer, Christos Kannas, Albert A Antolin, Paul Workman, Bissan Al-Lazikani
Publikováno v:
Nucleic Acids Research
canSAR (http://cansar.icr.ac.uk) is the largest, public, freely available, integrative translational research and drug discovery knowledgebase for oncology. canSAR integrates vast multidisciplinary data from across genomic, protein, pharmacological,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::550de7116fa055897e0a9e92c7a5b41a
https://doi.org/10.1093/nar/gkaa1059
https://doi.org/10.1093/nar/gkaa1059
Autor:
Bugra Ozer, Betul Yuceturk, Ilknur Suer, Mustafa Ozen, Asuman Koparir, Omer Faruk Karatas, Seda Salman Yilmaz
Publikováno v:
American Journal of Medical Genetics Part A. 179:579-587
Purpose Martsolf (MS) and Warburg micro syndromes (WARBM) are rare autosomal recessive inherited allelic disorders, which share similar clinical features including microcephaly, intellectual disability, brain malformations, ocular abnormalities, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2475c24c3a69c456e461c448f2eea9b
https://doi.org/10.1002/ajmg.a.61065
https://doi.org/10.1002/ajmg.a.61065
Autor:
Elizabeth A. Coker, Adam Stewart, Bugra Ozer, Anna Minchom, Lisa Pickard, Ruth Ruddle, Suzanne Carreira, Sanjay Popat, Mary O'Brien, Florence Raynaud, Johann de Bono, Bissan Al-Lazikani, Udai Banerji
Publikováno v:
Molecular cancer therapeutics. 21(6)
We hypothesize that the study of acute protein perturbation in signal transduction by targeted anticancer drugs can predict drug sensitivity of these agents used as single agents and rational combination therapy. We assayed dynamic changes in 52 phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89213317a0225f93f724cfc9c3b3c713
https://pubmed.ncbi.nlm.nih.gov/35368084
https://pubmed.ncbi.nlm.nih.gov/35368084
Publikováno v:
SIU
26th IEEE Signal Processing and Communications Applications Conference (2018 : Izmir, Turkey)
As an alternative to Global Positioning System (GPS) position calculation can be achieved using Distance Measuring Equipments (DME). DME calculates and
As an alternative to Global Positioning System (GPS) position calculation can be achieved using Distance Measuring Equipments (DME). DME calculates and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc16bdb2911c460dc9f60d1180ea9d8f
https://doi.org/10.1109/siu.2018.8404414
https://doi.org/10.1109/siu.2018.8404414