Zobrazeno 1 - 10
of 269
pro vyhledávání: '"Buford L Nichols"'
Autor:
Byung-Hoo Lee, Like Yan, Robert J Phillips, Bradley L Reuhs, Kyra Jones, David R Rose, Buford L Nichols, Roberto Quezada-Calvillo, Sang-Ho Yoo, Bruce R Hamaker
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e59745 (2013)
For digestion of starch in humans, α-amylase first hydrolyzes starch molecules to produce α-limit dextrins, followed by complete hydrolysis to glucose by the mucosal α-glucosidases in the small intestine. It is known that α-1,6 linkages in starch
Externí odkaz:
https://doaj.org/article/ee7e1c4ce8234003a53d8a910edc479a
Autor:
Amy Hui-Mei Lin, Buford L Nichols, Roberto Quezada-Calvillo, Stephen E Avery, Lyann Sim, David R Rose, Hassan Y Naim, Bruce R Hamaker
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e35473 (2012)
For starch digestion to glucose, two luminal α-amylases and four gut mucosal α-glucosidase subunits are employed. The aim of this research was to investigate, for the first time, direct digestion capability of individual mucosal α-glucosidases on
Externí odkaz:
https://doaj.org/article/6d887bc7767e4887b756d25d11930218
Autor:
Anna M.R. Hayes, Clay Swackhamer, Roberto Quezada-Calvillo, Nancy F. Butte, Erwin E. Sterchi, Buford L. Nichols, Bruce R. Hamaker
Superior metabolic flexibility, or the ability to efficiently switch between oxidation of carbohydrate and fat, is inversely associated with obesity and type 2 diabetes. This study examined the impact of dietary carbohydrate digestion rate on metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4ec379350f23c133934e6f50cbbe01e
https://doi.org/10.1101/2023.01.08.523060
https://doi.org/10.1101/2023.01.08.523060
Publikováno v:
Curr Opin Gastroenterol
Purpose of review Disaccharidase testing, as applied to the evaluation of gastrointestinal disturbances is available but it is not routinely considered in the diagnostic work-up. The purpose of this review was to determine if disaccharidase testing i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63b9918ba9779aca620f4a5a67a43f0
https://doi.org/10.1097/mog.0000000000000614
https://doi.org/10.1097/mog.0000000000000614
Autor:
Buford L. Nichols, Karla J AuYeung, Ann O. Scheimann, Wikrom Karnsakul, Paul Wasuwanich, Susan Billet, Christine Karwowski, Thammasin Ingviya, Hassan Choudry
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-7 (2020)
BMC Gastroenterology
BMC Gastroenterology
Background Disaccharides such as lactose and sucrose are sugars commonly found in human diet. They are broken down by mucosal disaccharidases in the duodenum. Previous small studies found no associations between gastrointestinal (GI) symptoms and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9313e77e00752b7cdf37c63ff979de18
https://doi.org/10.1186/s12876-020-01443-4
https://doi.org/10.1186/s12876-020-01443-4
Autor:
Shaji Chacko, Like Y. Hasek, Roberto Quezada-Calvillo, Stephen E. Avery, J. Kenneth Fraley, Bruce R. Hamaker, Firoz A. Vohra, Buford L. Nichols
Publikováno v:
Nutrition (Burbank, Los Angeles County, Calif.). 78
Objectives Maltase-glucoamylase (Mgam) and sucrase-isomaltase (Si) are mucosal α-glucosidases required for the digestion of starch to glucose. We hypothesized that a dietary approach to reduce Mgam and Si activities can reduce glucose generation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3829a5ead324a10924cb7fc5be63cd1
https://pubmed.ncbi.nlm.nih.gov/32599415
https://pubmed.ncbi.nlm.nih.gov/32599415
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition. 66:S24-S29
The mucosal maltase enzymes are characterized by an activity that produces glucose from linear glucose polymers, assayed with the disaccharide maltose. The related enzyme isomaltase produces glucose from branched glucose polymers, assayed with palati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56dc53ad05aa30b44728a7c947b824e
https://doi.org/10.1097/mpg.0000000000001955
https://doi.org/10.1097/mpg.0000000000001955
Autor:
Marwa El Hindawy, Buford L. Nichols, Amy Hui-Mei Lin, Roberto Quezada-Calvillo, Shadi B. Kilani, Benjamin E. Hodges, Antone R. Opekun, Stephen E. Avery, Douglas G. Burrin, Sen-ichi Oda, Bruce R. Hamaker, Shaji Chacko
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition. 65:e35-e42
Background and objective Although named because of its sucrose hydrolytic activity, this mucosal enzyme plays a leading role in starch digestion because of its maltase and glucoamylase activities. Sucrase-deficient mutant shrews, Suncus murinus, were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785841cfae548423940180d738dde5f3
https://doi.org/10.1097/mpg.0000000000001561
https://doi.org/10.1097/mpg.0000000000001561
Autor:
Bruce R. Hamaker, Buford L. Nichols, David R. Rose, Amy Hui-Mei Lin, Roberto Quezada-Calvillo, Byung-Hoo Lee
Publikováno v:
Journal of Agricultural and Food Chemistry. 64:6487-6494
The mammalian mucosal α-glucosidase complexes, maltase-glucoamylase (MGAM) and sucrase-isomaltase (SI), have two catalytic subunits (N- and C-termini). Concurrent with the desire to modulate glycemic response, there has been a focus on di-/oligosacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6301ba99042dcaa99b6e7b117d70406f
https://doi.org/10.1021/acs.jafc.6b01816
https://doi.org/10.1021/acs.jafc.6b01816
Autor:
Yuzo Ninomiya, Robert F. Margolskee, Sankar Mohan, Ramana Kotha, Sunil K. Sukumaran, Noriatsu Shigemura, Shusuke Iwata, Roberto Quezada-Calvillo, Karen K. Yee, B. Mario Pinto, Buford L. Nichols
Publikováno v:
Proceedings of the National Academy of Sciences. 113:6035-6040
The primary sweet sensor in mammalian taste cells for sugars and noncaloric sweeteners is the heteromeric combination of type 1 taste receptors 2 and 3 (T1R2+T1R3, encoded by Tas1r2 and Tas1r3 genes). However, in the absence of T1R2+T1R3 (e.g., in Ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402f1032082c6edb5f790c7303be4d7f
https://doi.org/10.1073/pnas.1520843113
https://doi.org/10.1073/pnas.1520843113