Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Buffie Clodfelder-Miller"'
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18495- (2023)
This neuroanatomical study in four, adult, Sprague-Dawley female rats quantified the number of Urothelial (labeled by intravesical DiI dye administration) and Non-Urothelial (labeled by intraparenchymal injection of Fast blue dye) bladder primary aff
Externí odkaz:
https://doaj.org/article/0636fdeecb42467c82327d26de386ee0
Publikováno v:
Frontiers in Systems Neuroscience, Vol 16 (2022)
Bladder pain and hypersensitivity to bladder filling are clinically common, but animal models examining syndromes with these features are limited. A rat model of bladder hypersensitivity produced by neonatal bladder inflammation (NBI) has been report
Externí odkaz:
https://doaj.org/article/0d039faf0d73478dbd698e5055bfd7d1
Autor:
Timothy J. Ness, Cary DeWitte, Jennifer J. DeBerry, Morgan P. Hart, Buffie Clodfelder-Miller, Jianguo G. Gu, Jennifer Ling, Alan Randich
Publikováno v:
Frontiers in Pain Research, Vol 2 (2021)
This report describes methodological and exploratory investigations of the zymosan-induced neonatal bladder inflammation (NBI) model of interstitial cystitis/bladder pain syndrome (IC/BPS) in female rats. These results validate and extend the current
Externí odkaz:
https://doaj.org/article/4a316e54200f40fc9879f19edc02f464
Publikováno v:
Neurourol Urodyn
AIMS: Neuromodulation (nerve stimulation) can produce analgesia. One form, bilateral pudendal nerve stimulation (bPNS), suppresses responses to urinary bladder distension (UBD) in hypersensitive rats. Drugs can modify this effect (e.g., benzodiazepin
Publikováno v:
Neuroscience Letters. 686:181-185
Bilateral electrical pudendal nerve stimulation (bPNS) reduces bladder hypersensitivity in rat models of bladder pain and anecdotally reduces pain in humans with pelvic pain of urologic origin. The spinal neurochemical mechanisms of this antinocicept
Autor:
Timothy J. Ness, Buffie Clodfelder-Miller, Jennifer J. DeBerry, Hirosato Kanda, Judy Creighton, Jianguo G. Gu
Publikováno v:
Brain Res
There is mounting evidence underscoring a role for the urothelium in urinary bladder sensation. Previous functional studies have identified bladder primary afferents with mechanosensitive properties suggesting urothelial innervation and/or communicat
Publikováno v:
Anesth Analg
Background Neuromodulation, as a therapeutic modality for pain treatment, is an alternative to opioid therapies and therefore receiving increased interest and use. Neuromodulation at a peripheral nerve target, in the form of bilateral electrical pude
Autor:
Jianguo G. Gu, Jennifer J. DeBerry, Buffie Clodfelder-Miller, Hirosato Kanda, Timothy J. Ness
Publikováno v:
Brain Research. 1648:81-89
Pelvic nerve (PN) bladder primary afferent neurons were retrogradely labeled by intraparenchymal (IPar) microinjection of fluorescent tracer or intravesical (IVes) infusion of tracer into the bladder lumen. IPar and IVes techniques labeled two distin
Publikováno v:
Regional anesthesia and pain medicine.
Background and objectivesBilateral electrical pudendal nerve stimulation (bPNS) reduces bladder hypersensitivity in rat models and anecdotally reduces pain in humans with pelvic pain of urologic origin. Concomitant opioids are known to alter response
Autor:
Dipak Thakur, Elizabeth A. Richardson, Jonathan Bones, Shemeica Binns, Tomas Rejtar, Buffie Clodfelder-Miller, Dennis C. Sgroi, Sangwon Cha, Sonika Dahiya, Dongdong Wang, Barry L. Karger
Publikováno v:
Journal of Chromatography A. 1218:8168-8174
Precise proteomic profiling of limited levels of disease tissue represents an extremely challenging task. Here, we present an effective and reproducible microproteomic workflow for sample sizes of only 10,000 cells that integrates selective sample pr