Using Artificial Intelligence With Natural Language Processing to Combine Electronic Health Record’s Structured and Free Text Data to Identify Nonvalvular Atrial Fibrillation to Decrease Strokes and Death: Evaluation and Case-Control Study

Autor: Peter L Elkin, Sarah Mullin, Jack Mardekian, Christopher Crowner, Sylvester Sakilay, Shyamashree Sinha, Gary Brady, Marcia Wright, Kimberly Nolen, JoAnn Trainer, Ross Koppel, Daniel Schlegel, Sashank Kaushik, Jane Zhao, Buer Song, Edwin Anand

Publikováno v: Journal of Medical Internet Research, Vol 23, Iss 11, p e28946 (2021)

BackgroundNonvalvular atrial fibrillation (NVAF) affects almost 6 million Americans and is a major contributor to stroke but is significantly undiagnosed and undertreated despite explicit guidelines for oral anticoagulation. ObjectiveThe aim of this

Externí odkaz: https://doaj.org/article/1a4ff3525b7e43418f934f3028012f6c

Parallel synthesis of condensed pyrimidine-thiones and their antitumor activities

Autor: Buer Song, Lifei Nie, Khurshed Bozorov, Rustamkhon Kuryazov, Haji Akber Aisa, Jiangyu Zhao

Publikováno v: Research on Chemical Intermediates. 49:1327-1348

Herein we studied the formation of thiones via C=O group conversion into the C=S functional group-based tricyclic pyrimidinone systems using Lawesson’s reagent and phosphorus pentasulfide as thionation agents. Naturally-occurring alkaloids deoxyvas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c4a65d452c5039c129aeacd6d89796
https://doi.org/10.1007/s11164-022-04912-5

Furo[2,3‐ d ]pyrimidines as Mackinazolinone/Isaindigotone Analogs: Synthesis, Modification, Antitumor Activity, and Molecular Docking Study

Autor: Buer Song, Lifei Nie, Khurshed Bozorov, Chao Niu, Rustamkhon Kuryazov, Haji Akber Aisa, Jiangyu Zhao

Publikováno v: Chemistry & Biodiversity. 20

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2412b66007270c7426fe7fdc934e35a2
https://doi.org/10.1002/cbdv.202201059

Design, combinatorial synthesis and cytotoxic activity of 2-substituted furo[2,3-d]pyrimidinone and pyrrolo[2,3-d]pyrimidinone library

Autor: Buer Song, Lifei Nie, Khurshed Bozorov, Rustamkhon Kuryazov, Jiangyu Zhao, Haji Akber Aisa

Publikováno v: Molecular diversity.

A facile protocol was developed for the combinatorial synthesis of furo[2,3-d]pyrimidinone and pyrrolo[2,3-d]pyrimidinone library via a one-pot condensation, from 2-amino furans/pyrroles. Herein reported process required a similar reaction condition,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1335fc4e3c50166b905de5c0559cfe7c
https://pubmed.ncbi.nlm.nih.gov/36197552

Using Artificial Intelligence With Natural Language Processing to Combine Electronic Health Record’s Structured and Free Text Data to Identify Nonvalvular Atrial Fibrillation to Decrease Strokes and Death: Evaluation and Case-Control Study

Autor: Sarah Mullin, Peter L. Elkin, Jane Y. Zhao, JoAnn B Trainer, Daniel R. Schlegel, Edwin Anand, Buer Song, Sashank Kaushik, Marcia Wright, Jack Mardekian, Gary Brady, Sylvester Sakilay, Kimberly Nolen, Ross Koppel, Christopher Crowner, Shyamashree Sinha

Publikováno v: Journal of Medical Internet Research
Elkin, P L, Mullin, S, Mardekian, J, Crowner, C, Sakilay, S, Sinha, S, Brady, G, Wright, M, Nolen, K, Trainer, J, Koppel, R, Schlegel, D, Kaushik, S, Zhao, J, Song, B & Anand, E 2021, ' Using Artificial Intelligence With Natural Language Processing to Combine Electronic Health Record's Structured and Free Text Data to Identify Nonvalvular Atrial Fibrillation to Decrease Strokes and Death : Evaluation and Case-Control Study ', Journal of Medical Internet Research, vol. 23, no. 11, e28946 . https://doi.org/10.2196/28946

Background Nonvalvular atrial fibrillation (NVAF) affects almost 6 million Americans and is a major contributor to stroke but is significantly undiagnosed and undertreated despite explicit guidelines for oral anticoagulation. Objective The aim of thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ac7832e97167102bdda0c50ca42f4b
https://doi.org/10.2196/28946