Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Budhaditya Mukherjee"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Visceral leishmaniasis (VL) is the most severe type of leishmaniasis which is caused by infection of Leishmania donovani complex. In the BALB/c mouse model of VL, multinucleated giant cells (MGCs) with heavy parasite infection consist of the largest
Externí odkaz:
https://doaj.org/article/26c8dfea7f424eef9baadfef6d3823bd
Autor:
Oishika Das, Jayanta Kundu, Atanu Ghosh, Anupam Gautam, Souradeepa Ghosh, Mainak Chakraborty, Aaheli Masid, Samiran Sona Gauri, Debmalya Mitra, Moumita Dutta, Budhaditya Mukherjee, Surajit Sinha, Moumita Bhaumik
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Introduction and objectiveCholesterol homeostasis is a culmination of cellular synthesis, efflux, and catabolism to important physiological entities where short chain fatty acid, butyrate embodied as a key player. This discourse probes the mechanisti
Externí odkaz:
https://doaj.org/article/a330c7fc5aa9497386ca7472619c2499
Structural insights into an atypical secretory pathway kinase crucial for Toxoplasma gondii invasion
Autor:
Gaëlle Lentini, Rouaa Ben Chaabene, Oscar Vadas, Chandra Ramakrishnan, Budhaditya Mukherjee, Ved Mehta, Matteo Lunghi, Jonas Grossmann, Bohumil Maco, Rémy Visentin, Adrian B. Hehl, Volodymyr M. Korkhov, Dominique Soldati-Favre
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Host cell invasion by Toxoplasma gondii depends on the heavily phosphorylated RON complex, but the relevance and regulation of these modifications are not understood. Here, the authors identify the kinase RON13 as a key virulence factor, determine it
Externí odkaz:
https://doaj.org/article/b99ddeb7c5ca4acfb20ea9d41fb9e96c
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/98d09eb3c9cc4bf6a8335cae5635ad07
Autor:
Supratim Pradhan, Snehlata, Debolina Manna, Subir Karmakar, Manoj Kumar Singh, Arijit Bhattacharya, Budhaditya Mukherjee, Joydeep Paul
Publikováno v:
Heliyon, Vol 8, Iss 7, Pp e09868- (2022)
Immunotherapeutic strategies against visceral leishmaniasis (VL) are pertinent because of the emergence of resistance against existing chemotherapy, coupled with their toxicity and high costs. Various bioactive components with potential immunomodulat
Externí odkaz:
https://doaj.org/article/f9a88dc19a7a48ac9fe1f9d7d597c77d
Autor:
Souradeepa Ghosh, Souvik Biswas, Sandip Mukherjee, Arijit Pal, Aaditya Saxena, Shyam Sundar, Jean-Claude Dujardin, Soumen Das, Syamal Roy, Rupkatha Mukhopadhyay, Budhaditya Mukherjee
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The extent of susceptibility towards miltefosine (Mil), amphotericin B (AmpB), and paromomycin (Paro) was measured among 19 clinical isolates of Leishmania donovani (LD). Thirteen of these clinical isolates were reported to exhibit low susceptibility
Externí odkaz:
https://doaj.org/article/4cd0e802605446829bac61066651e28c
Autor:
Sandip Mukherjee, Supratim Pradhan, Souradeepa Ghosh, Shyam Sundar, Shantanabha Das, Budhaditya Mukherjee, Syamal Roy
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Previously we have shown that long term oral treatment of tricyclic-antidepressant-drug, imipramine, against experimental visceral leishmaniasis, results in clearance of organ parasites, regardless of input infection, either with antimony-sensitive (
Externí odkaz:
https://doaj.org/article/7d43559b02fc4cf69ba4466283baefa0
Autor:
Sunil Kumar Dogga, Budhaditya Mukherjee, Damien Jacot, Tobias Kockmann, Luca Molino, Pierre-Mehdi Hammoudi, Ruben C Hartkoorn, Adrian B Hehl, Dominique Soldati-Favre
Publikováno v:
eLife, Vol 6 (2017)
Micronemes and rhoptries are specialized secretory organelles that deploy their contents at the apical tip of apicomplexan parasites in a regulated manner. The secretory proteins participate in motility, invasion, and egress and are subjected to prot
Externí odkaz:
https://doaj.org/article/b26e3a04d06d4c7a86a42bd8b14b27ed
Autor:
Sandip Mukherjee, Budhaditya Mukherjee, Rupkatha Mukhopadhyay, Kshudiram Naskar, Shyam Sundar, Jean Claude Dujardin, Anjan Kumar Das, Syamal Roy
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 12, p e1987 (2012)
BACKGROUND: In an endeavor to find an orally active and affordable antileishmanial drug, we tested the efficacy of a cationic amphiphilic drug, imipramine, commonly used for the treatment of depression in humans. The only available orally active anti
Externí odkaz:
https://doaj.org/article/4150a6b253cf4bf3ac9e385b6b41e2a4