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Publikováno v:
Physiological Reports
Sensing of hypoxia and acidosis in arterial chemoreceptors is thought to be mediated through the inhibition of TASK and possibly other (e.g., BKC a ) potassium channels which leads to membrane depolarization, voltage-gated Ca-entry, and neurosecretio
Publikováno v:
Scientific reports, vol 8, iss 1
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Cardiovascular disease is the most prevalent age-related illness worldwide, causing approximately 15 million deaths every year. Hypertension is central in determining cardiovascular risk and is a strong predictive indicator of morbidity and mortality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::36a7e44773cc8a3bcce665d6f6305678
https://escholarship.org/uc/item/7mt9h6hb
https://escholarship.org/uc/item/7mt9h6hb
This thesis investigates the role anaesthetics play in the depression of the acute hypoxic and hypercapnic ventilatory response. Particular attention is paid to TASK (TWIK related acid sensitive potassium) channels that are known to be sensitive to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::55a54404aa7be8d9bdeb00fecec5f9e8
https://ora.ox.ac.uk/objects/uuid:845622fb-c4e5-46b5-9bdf-b8603200f83f
https://ora.ox.ac.uk/objects/uuid:845622fb-c4e5-46b5-9bdf-b8603200f83f
Autor:
Buckler, K, Gurney, A, Nurse, C, López-Barneo, J, Kemp, P, Kummer, W, Sylvester, J, Kumar, P, Archer, S, Chandel, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::8aef7f3d6ee31bed8aa6f9e7ec439568
https://ora.ox.ac.uk/objects/uuid:ae7dbd65-1897-4484-aaf1-1a96d63659a2
https://ora.ox.ac.uk/objects/uuid:ae7dbd65-1897-4484-aaf1-1a96d63659a2