Synthesis, Biological Evaluation and Molecular Modelling of 2'-Hydroxychalcones as Acetylcholinesterase Inhibitors.

Autor: Sukumaran SD; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. shivanesri@yahoo.com., Chee CF; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. cfchee@yahoo.com.; Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia. cfchee@yahoo.com., Viswanathan G; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. geethaviswa@gmail.com., Buckle MJ; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. buckle@um.edu.my., Othman R; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. rozanaothman@um.edu.my., Abd Rahman N; Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia. noorsaadah@um.edu.my., Chung LY; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. chungly@um.edu.my.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2016 Jul 22; Vol. 21 (7). Date of Electronic Publication: 2016 Jul 22.

Flavonoids with M1 muscarinic acetylcholine receptor binding activity.

Autor: Swaminathan M; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. oosh_mey@yahoo.com., Chee CF; Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia. cfchee@yahoo.com., Chin SP; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. xueping.chin@gmail.com., Buckle MJ; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. buckle@um.edu.my., Rahman NA; Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia. noorsaadah@um.edu.my., Doughty SW; School of Pharmacy, University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia. stephen.doughty@nottingham.edu.my., Chung LY; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. chungly@um.edu.my.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2014 Jun 27; Vol. 19 (7), pp. 8933-48. Date of Electronic Publication: 2014 Jun 27.

Study the antiviral activity of some derivatives of tetracycline and non-steroid anti inflammatory drugs towards dengue virus.

Autor: Rothan HA; Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia., Buckle MJ; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia., Ammar YA; Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia., Mohammadjavad P; Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia., Shatrah O; Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia., Noorsaadah AR; Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia., Rohana Y; Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

Publikováno v: Tropical biomedicine [Trop Biomed] 2013 Dec; Vol. 30 (4), pp. 681-90.

Induction of selective cytotoxicity and apoptosis in human T4-lymphoblastoid cell line (CEMss) by boesenbergin a isolated from boesenbergia rotunda rhizomes involves mitochondrial pathway, activation of caspase 3 and G2/M phase cell cycle arrest.

Autor: Ng KB; UPM-MAKNA Cancer Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, Malaysia., Bustamam A, Sukari MA, Abdelwahab SI, Mohan S, Buckle MJ, Kamalidehghan B, Nadzri NM, Anasamy T, A Hadi AH, Rahman HS

Publikováno v: BMC complementary and alternative medicine [BMC Complement Altern Med] 2013 Feb 22; Vol. 13, pp. 41. Date of Electronic Publication: 2013 Feb 22.

Homology modeling of the human 5-HT1A, 5-HT 2A, D1, and D2 receptors: model refinement with molecular dynamics simulations and docking evaluation.

Autor: Yap BK; Department of Pharmacy, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia., Buckle MJ, Doughty SW

Publikováno v: Journal of molecular modeling [J Mol Model] 2012 Aug; Vol. 18 (8), pp. 3639-55. Date of Electronic Publication: 2012 Feb 22.