Zobrazeno 1 - 10
of 1 283
pro vyhledávání: '"Buck E"'
Autor:
Richard Laforest, Anchal Ghai, Tyler J. Fraum, Reiko Oyama, Jennifer Frye, Helen Kaemmerer, Greg Gaehle, Tom Voller, Cedric Mpoy, Buck E. Rogers, Mark Fiala, Kooresh I. Shoghi, Samuel Achilefu, Michael Rettig, Ravi Vij, John F. DiPersio, Sally Schwarz, Monica Shokeen, Farrokh Dehdashti
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100565- (2024)
Externí odkaz:
https://doaj.org/article/38608f17eba846d598f2c9622e317790
Autor:
Nadia Benabdallah, Hanwen Zhang, Ryan Unnerstall, Amanda Fears, Lucy Summer, Michael Fassbender, Buck E. Rodgers, Diane Abou, Valery Radchenko, Daniel L. J. Thorek
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Background 44Sc/47Sc is an attractive theranostic pair for targeted in vivo positron emission tomographic (PET) imaging and beta-particle treatment of cancer. The 44Ti/44Sc generator allows daily onsite production of this diagnostic isotope,
Externí odkaz:
https://doaj.org/article/0b81433194ff4a17b78c6f359d2e1aa6
Autor:
Hanwen Zhang, Diane Abou, Peng Lu, Abbie Meghan Hasson, Alexandria Villmer, Nadia Benabdallah, Wen Jiang, David Ulmert, Sean Carlin, Buck E. Rogers, Norman F. Turtle, Michael R. McDevitt, Brian Baumann, Brian W. Simons, Farrokh Dehdashti, Dong Zhou, Daniel L. J. Thorek
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The growing interest and clinical translation of alpha particle (α) therapies brings with it new challenges to assess target cell engagement and to monitor therapeutic effect. Noninvasive imaging has great potential to guide α-treatment an
Externí odkaz:
https://doaj.org/article/9b792b047c414428bbbdfc607f1aa8a7
Autor:
David M. Zhang, Rachita Navara, Tiankai Yin, Jeffrey Szymanski, Uri Goldsztejn, Camryn Kenkel, Adam Lang, Cedric Mpoy, Catherine E. Lipovsky, Yun Qiao, Stephanie Hicks, Gang Li, Kaitlin M. S. Moore, Carmen Bergom, Buck E. Rogers, Clifford G. Robinson, Phillip S. Cuculich, Julie K. Schwarz, Stacey L. Rentschler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Noninvasive cardiac radiotherapy may effectively manage ventricular tachycardia in refractory patients, but its radiobiologic mechanisms of action are unclear. Here, the authors show that photon radiation durably and favourably reprograms cardiac con
Externí odkaz:
https://doaj.org/article/b87d769fbd7248d484a32dad47327e5a
Autor:
Sreeja Sreekumar, Dong Zhou, Cedric Mpoy, Elsa Schenk, Jalen Scott, Jeffrey M. Arbeit, Jinbin Xu, Buck E. Rogers
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3083 (2023)
There is an unmet need for better therapeutic strategies for advanced prostate cancer. Poly (ADP-ribose) polymerase-1 (PARP-1) is a chromatin-binding DNA repair enzyme overexpressed in prostate cancer. This study evaluates whether PARP-1, on account
Externí odkaz:
https://doaj.org/article/f6936fb1be32464689d79c50d9919317
Autor:
Truc T. Huynh, Ellen M. van Dam, Sreeja Sreekumar, Cedric Mpoy, Benjamin J. Blyth, Fenella Muntz, Matthew J. Harris, Buck E. Rogers
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 728 (2022)
The gastrin-releasing peptide receptor (GRPR) is a promising molecular target for imaging and therapy of prostate cancer using bombesin peptides that bind to the receptor with high affinity. Targeted copper theranostics (TCTs) using copper radionucli
Externí odkaz:
https://doaj.org/article/6b47add857c6406db5f89e77d7494c0d
Autor:
Dong Zhou, Huaping Chen, Cedric Mpoy, Sadia Afrin, Buck E. Rogers, Joel R. Garbow, John A. Katzenellenbogen, Jinbin Xu
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 565 (2021)
Poly (ADP-ribose) polymerase-1 (PARP-1) is a critical enzyme in the DNA repair process and the target of several FDA-approved inhibitors. Several of these inhibitors have been radiolabeled for non-invasive imaging of PARP-1 expression or targeted rad
Externí odkaz:
https://doaj.org/article/b0ae44e49df347f4b526ff6761ede015
Autor:
Huaping Chen, Sadia Afrin, Yingqiu Guo, Wenhua Chu, Tammie L.S. Benzinger, Buck E. Rogers, Joel R. Garbow, Joel S. Perlmutter, Dong Zhou, Jinbin Xu
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8860 (2020)
MTH1 (MutT homolog 1) or NUDT1 (Nudix Hydrolase 1), also known as oxidized purine nucleoside triphosphatase, has potential as a biomarker for monitoring cancer progression and quantifying target engagement for relevant therapies. In this study, we va
Externí odkaz:
https://doaj.org/article/354da1a554fd4da787ad6f0b3eea8901
Autor:
Igor P. Dmitriev, Elena A. Kashentseva, Kenneth H. Kim, Qiana L. Matthews, Stephanie S. Krieger, Jesse J. Parry, Kim N. Nguyen, Walter J. Akers, Samuel Achilefu, Buck E. Rogers, Ronald D. Alvarez, David T. Curiel
Publikováno v:
Molecular Imaging, Vol 13 (2014)
A significant limiting factor to the human clinical application of conditionally replicative adenovirus (CRAd)-based virotherapy is the inability to noninvasively monitor these agents and their potential persistence. To address this issue, we propose
Externí odkaz:
https://doaj.org/article/11c8a7d66c1b42468dc6db1106f96ab5
Autor:
Lei Liu, Buck E. Rogers, Natalia Aladyshkina, Bing Cheng, Stephen J. Lokitz, David T. Curiel, J. Michael Mathis
Publikováno v:
Molecular Imaging, Vol 13 (2014)
Using adenovirus (Ad)-based vectors is a promising strategy for novel cancer treatments; however, current tracking approaches in vivo are limited. The C-terminus of the Ad minor capsid protein IX (pIX) can incorporate heterologous reporters to monito
Externí odkaz:
https://doaj.org/article/aeac5afad8a1482ba823b7388ae2a7ce