Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Buck A. Rhodes"'
Autor:
Mathew L. Thakur, M. Patel, S. L. Kipper, L. Diggles, Buck A. Rhodes, H. L. Pham, R. Ahdoot, Christina A. Minami, Carol S. Marcus, T. Smith
Publikováno v:
Nuclear Medicine Communications. 22:513-519
LeuTech® is a 99 Tc m labelled, anti-CD15, IgM, murine monoclonal antibody shown to have high affinity (K d =10 -11 M) for CD15 receptors (5.1 x 105/cell) expressed on human neutrophils. LeuTech® was injected directly, intravenously, and its effica
Publikováno v:
Seminars in Nuclear Medicine. 26:77-84
On the average, radiopharmacists spend about 17.2% of their time in clinical activities if their practice setting is in an institution, and about 8.5% of their time if their practice setting is in a centralized nuclear pharmacy. A recent survey of ra
Autor:
Paul O. Zamora, Buck A. Rhodes, Hans-Jürgen Biersack, Stefan Gulhke, Furn F. Knapp, Hans Bender, Daniella Diekmann
Publikováno v:
International Journal of Cancer. 65:214-220
The therapeutic potential of the somatostatin analogue RC-160 radiolabeled with 188 Re was evaluated in nude mice bearing xenografts of human prostate adenocarcinoma. 188 Re-RC-160 was selectively retained in both DU-145 and PC-3 tumors following dir
Autor:
Buck A. Rhodes, Paul O. Zamora
Publikováno v:
Bioconjugate Chemistry. 3:493-498
99mTc is widely thought to directly bind proteins through thiolate groups of cysteine residues, resulting in Tc-cysteinyl-protein bonds. Chemical reduction of disulfide bonds in proteins is widely used to generate thiolates with the goal of increasin
Autor:
Buck A. Rhodes
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 18:667-676
The direct labeling of antibodies and antibody fragments to form a highly stable bond between technetium and the sulfide groups of proteins is now well established. To optimize this reaction, the antibody protein must have sufficient reactive sulfide
Autor:
Jacek Capala, Michael J. Marek, Robert A. Fenstermaker, Buck A. Rhodes, Michael Q. Bailey, Rolf F. Barth
Publikováno v:
Bioconjugate chemistry. 8(3)
High grade gliomas may have amplified expression of the epidermal growth factor receptor (EGFR) gene c-erb-B, which often is associated with increased expression of transmembrane EGFR. The purpose of the present study was to develop a method for labe
Publikováno v:
Nuclear medicine and biology. 21(2)
Thin layer chromatography (TLC) was used to monitor binding of radiolabeled antibodies to cells. Labeled antibodies were reacted with cells and aliquots chromatographed on serum-blocked, ITLC strips. The cell-antibody complexes remain at the origin a
Publikováno v:
Magnetic Resonance Imaging. 13:XXI
Biomodulators, in conjunction with antibodies, tumor-specific agents or conjugates thereof, optionally linked to imaging-active moieties, can be administered to a host to enhance images thereof, e.g., NMR-, X-ray- or radioimages, preferably by increa
Autor:
Buck A. Rhodes
Publikováno v:
Seminars in Nuclear Medicine. 4:281-293
Labeled albumins for blood-pool, albumin-metabolism, and gastrointestinal-blood-loss studies have been readily available for years, and their clinical use is well established. Labeled albumin for cisternography was once widely used; now it is restric
Autor:
Richard M. Fulks, Buck A. Rhodes, Madhira D. Ram, Cecilia M. Fenoglio-Preiser, Christopher O. A. Berry, Paul O. Zamora, Keshab D. Pant
Publikováno v:
American Journal of Clinical Pathology. 86:1-9
A goat anti-serum was prepared against mucinous ovarian cyst fluid and absorbed with normal colon and a variety of normal tissues until the only residual immunoreactivity was directed against colon cancer and ovarian tumor mucin. The set of antigenic