Výsledky vyhledávání - "Buchholz Ina"

Report

Drug-induced activation of integrin alpha IIb beta 3 leads to minor localized structural changes

Autor: Janke, Una, Kulke, Martin, Buchholz, Ina, Geist, Norman, Langel, Walter, Delcea, Mihaela

Integrins are transmembrane proteins involved in hemostasis, wound healing, immunity and cancer. In response to intracellular signals and ligand binding, integrins adopt different conformations: the bent (resting) form; the intermediate extended form

Externí odkaz: http://arxiv.org/abs/2012.10527

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Lysine residues control the conformational dynamics of beta 2-glycoprotein I

Autor: Buchholz, Ina, Nestler, Peter, Köppen, Susan, Delcea, Mihaela

One of the major problems in the study of the dynamics of proteins is the visualization of changing conformations that are important for processes ranging from enzyme catalysis to signaling. A protein exhibiting conformational dynamics is the soluble

Externí odkaz: http://arxiv.org/abs/2012.10515

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Report

The impact of physiological stress conditions on protein structure and trypsin inhibition of serine protease inhibitor Kazal type 1 (SPINK1) and its N34S variant

Autor: Buchholz, Ina, Nagel, Felix, Klein, Annelie, Wagh, Preshit R., Mahajan, Ujjwal M., Greinacher, Andreas, Lerch, Markus M., Mayerle, Julia, Delcea, Mihaela

One of the most common mutations in the serine protease inhibitor Kazal type 1 (SPINK1) gene is the N34S variant which is strongly associated with chronic pancreatitis. Although it is assumed that N34S mutation constitutes a high-risk factor, the und

Externí odkaz: http://arxiv.org/abs/2012.10197

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Akademický článek

Genetic tools for the investigation of Roseobacter clade bacteria

Autor: Tielen Petra, Wagner-Doebler Irene, Schobert Max, Drepper Thomas, Buchholz Ina, Piekarski Tanja, Jahn Dieter

Publikováno v: BMC Microbiology, Vol 9, Iss 1, p 265 (2009)

Abstract Background The Roseobacter clade represents one of the most abundant, metabolically versatile and ecologically important bacterial groups found in marine habitats. A detailed molecular investigation of the regulatory and metabolic networks o

Externí odkaz: https://doaj.org/article/2b75d0b304c143c2a76931504d507d5c