Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bubing Zeng"'
Publikováno v:
Chemical Communications. 56:13876-13879
Structure-guided engineering of Pseudomonas dacunhaeL-aspartate β-decarboxylase (AspBDC) resulted in a double mutant (R37A/T382G) with remarkable 15 400-fold improvement in specific activity reaching 216 mU mg−1, towards the target substrate 3(R)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b286bf8ec9aa2366a8008b86a93118
https://doi.org/10.1039/d0cc05871h
https://doi.org/10.1039/d0cc05871h
Publikováno v:
Organic Letters. 17:2732-2735
A diastereodivergent catalytic asymmetric Michael addition of 2-oxindoles to α,β-unsaturated ketones has been successfully developed with two complementary chiral diamine catalysts, affording chiral 3,3-disubstituted oxindoles with two adjacent chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788d41134e39eafb6e8ce085a50b882e
https://doi.org/10.1021/acs.orglett.5b01149
https://doi.org/10.1021/acs.orglett.5b01149
Autor:
Shuangjie Wang, Jian Wang, Wenping Xu, Chengshui Chen, Aijie Xin, Long Yang, Jun Yang, Wenwen Gu, Bubing Zeng, Xu Zhang, Nian Dong, Guowu Chen, Xiaoxi Sun, Zhong Ni
Publikováno v:
Scientific Reports
Tamoxifen is administered for estrogen receptor positive (ER+) breast cancers, but it can induce uterine endometrial cancer and non-alcoholic fatty liver disease (NAFLD). Importantly, ten years of tamoxifen treatment has greater protective effect aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf86de6735bcc3ccbb787c45657dda5
https://doi.org/10.1038/srep43940
https://doi.org/10.1038/srep43940
Autor:
Weiliang Zhu, Bo Li, He-Yao Wang, Jiye Shi, Kaixian Chen, Yong Zhang, Gaihong Wang, Bubing Zeng, Xian-Gui Huang, Zhijian Xu
Publikováno v:
European Journal of Medicinal Chemistry. 77:204-210
The present study discovers multiple N-substituted 3-arylisoquinolone derivatives as antitumor agents originating from O-substituted 3-arylisoquinolines via [2,3] or [3,3] rearrangement. The current [2,3] rearrangement of epoxy or acetal O-substituen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1cc5275380c9d87fcf2319bc2e2fff
https://doi.org/10.1016/j.ejmech.2014.03.008
https://doi.org/10.1016/j.ejmech.2014.03.008
Autor:
Hong-Wei Shi, Kunqian Yu, Weihua Li, Guixia Liu, Xiangui Huang, Yun Tang, Bubing Zeng, Congying Xu
Publikováno v:
International Journal of Quantum Chemistry. 113:1339-1348
In asymmetric Michael addition between ketones and nitroolefins catalyzed by L-proline, we observed that it was benzoic acid or its derivatives rather than other proton acid that could accelerate the reaction greatly, and different benzoic acid deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74c96bbc6734725b497577ba9b356342
https://doi.org/10.1002/qua.24297
https://doi.org/10.1002/qua.24297
Publikováno v:
ChemInform. 46
Either anti- or syn-configured oxindole derivatives possessing a vicinal quaternary and tertiary stereogenic center are obtained with high enantioselectivities by use of two complementary chiral diamine catalysts and through modifying the substrates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::004c9ec69eea3819cfe6e47755cf555f
https://doi.org/10.1002/chin.201542149
https://doi.org/10.1002/chin.201542149
Autor:
Kaixian Chen, Yong Zhang, Xian-Gui Huang, Zhijian Xu, Bo Li, Bubing Zeng, Gaihong Wang, Jiye Shi, He-Yao Wang, Weiliang Zhu
Publikováno v:
ChemInform. 45
A variety of N-substituted 3-arylisoquinolone derivatives are synthesized via [2,3] or [3,3] rearrangement reactions of corresponding O-substituted 3-arylisoquinolines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d47dbe89400ca9010262923ac07bbca
https://doi.org/10.1002/chin.201439181
https://doi.org/10.1002/chin.201439181
Autor:
Jingshan Shen, He-Yao Wang, Weiliang Zhu, Kaixian Chen, Mu Yang, Bo Li, Zhijian Xu, Bubing Zeng, Gaihong Wang
Publikováno v:
ChemInform. 45
The B-ring of Benzoazepinoisoquinolones 1a-b was successfully constructed by Pomeranz-Fritsch reaction. The key intermediates 5a-b could be transformed from 9a-b via Overman rearrangement. The bioassay showed that 11 compounds are more active than so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fea2f1505f0653aec3949c0774be731
https://doi.org/10.1002/chin.201419184
https://doi.org/10.1002/chin.201419184
Autor:
Gaihong Wang, Zhijian Xu, Weiliang Zhu, Mu Yang, Jingshan Shen, Kaixian Chen, He-Yao Wang, Bo Li, Bubing Zeng
Publikováno v:
European journal of medicinal chemistry. 70
The B-ring of Benzoazepinoisoquinolones 1a-b was successfully constructed by Pomeranz-Fritsch reaction. The key intermediates 5a-b could be transformed from 9a-b via Overman rearrangement. The bioassay showed that 11 compounds are more active than so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8033ed1bd52180db9e5f71f33a839b41
https://pubmed.ncbi.nlm.nih.gov/24215818
https://pubmed.ncbi.nlm.nih.gov/24215818
Autor:
Zhongyu, Xu, Jiangmeng, Ren, Qiufang, Jing, Fuzheng, Ren, Mengting, Huang, Wenrui, Ding, Bubing, Zeng
Publikováno v:
RSC Advances; 2018, Vol. 8 Issue 60, p34726-34732, 7p