Zobrazeno 1 - 10
of 1 078
pro vyhledávání: '"Bub1"'
Autor:
HOU Yiying, WEI Fang
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 12, Pp 1717-1721 (2024)
The BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B) maintains a high fidelity of mitotic chromosome segregation by preventing the initiation of anaphase without the attachment of one or more kinetochore to the spindle, and plays a major rol
Externí odkaz:
https://doaj.org/article/5562fd34179b48829b44d642b0663cdd
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Melanoma is the most dangerous form of skin cancer. Hence, a better understanding of molecular mechanisms in melanoma pathogenesis is urgently needed, which provides a new insight into the therapy of melanoma. DTL gene is screened out in mel
Externí odkaz:
https://doaj.org/article/f56dfc8c86f04dc5a0139c4b5d53229f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Small cell lung cancer (SCLC) is a very aggressive tumor. Abnormal expression of BUB1 has been reported in several cancer types, wherein it plays a range of functional roles. This work aimed to elucidate the functional significance and molec
Externí odkaz:
https://doaj.org/article/9801f8bbf6704a1db5861d55a601133e
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract This study aimed to evaluate the expression and clinical significance of budding uninhibited by benzimidazole 1 (BUB1) and BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B) in endometrial carcinoma (EC). BUB1 and BUBIB expressions we
Externí odkaz:
https://doaj.org/article/b227d03c48ac48a2a89d4b95dc7b93b6
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103594- (2024)
Mutations in the Budding uninhibited by benzimidazoles (BUB1) gene were recently associated with neurodevelopmental disorders (Carvalhal et al., 2022). Here, we describe the generation and characterization of two induced pluripotent stem cells (iPSC)
Externí odkaz:
https://doaj.org/article/583031031b864f3d9f855ca462eeedd8
Autor:
Sushmitha Sriramulu, Shivani Thoidingjam, Wei-Min Chen, Oudai Hassan, Farzan Siddiqui, Stephen L. Brown, Benjamin Movsas, Michael D. Green, Anthony J. Davis, Corey Speers, Eleanor Walker, Shyam Nyati
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer subtype often treated with radiotherapy (RT). Due to its intrinsic heterogeneity and lack of effective targets, it is crucial to identify novel mole
Externí odkaz:
https://doaj.org/article/bec285331eba422bb5e204315df583c6
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Sushmitha Sriramulu, Shivani Thoidingjam, Farzan Siddiqui, Stephen L. Brown, Benjamin Movsas, Eleanor Walker, Shyam Nyati
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 625 (2024)
BUB1 is overexpressed in most human solid cancers, including breast cancer. Higher BUB1 levels are associated with a poor prognosis, especially in patients with triple-negative breast cancer (TNBC). Women with TNBC often develop resistance to chemoth
Externí odkaz:
https://doaj.org/article/3134a2ef6bee4cc8b1385d114f33931f