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Akademický článek

Safety and immunogenicity of heterologous boosting with orally administered aerosolized bivalent adenovirus type-5 vectored COVID-19 vaccine and B.1.1.529 variant adenovirus type-5 vectored COVID-19 vaccine in adults 18 years and older: a randomized, double blinded, parallel controlled trial

Autor: Jia-Wei Xu, Bu-Sen Wang, Ping Gao, Hai-Tao Huang, Fei-Yu Wang, Wei Qiu, Yuan-Yuan Zhang, Yu Xu, Jin-Bo Gou, Lin-Ling Yu, Xuan Liu, Rui-Jie Wang, Tao Zhu, Li-Hua Hou, Qing- Wang

Publikováno v: Emerging Microbes and Infections, Vol 13, Iss 1 (2024)

ABSTRACTVaccination strategies that can induce a broad spectrum immune response are important to enhance protection against SARS-CoV-2 variants. We conducted a randomized, double-blind and parallel controlled trial to evaluate the safety and immunoge

Externí odkaz: https://doaj.org/article/cee3a761eea34cc3af4042b39af51639

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Safety and immunogenicity of heterologous boosting with orally aerosolised or intramuscular Ad5-nCoV vaccine and homologous boosting with inactivated vaccines (BBIBP-CorV or CoronaVac) in children and adolescents: a randomised, open-label, parallel-controlled, non-inferiority, single-centre study

Publikováno v: The Lancet Respiratory Medicine.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c60a1edbf99ca19266748bd58a4964ad
https://doi.org/10.1016/s2213-2600(23)00129-7

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Safety and immunogenicity of aerosolised Ad5-nCoV, intramuscular Ad5-nCoV, or inactivated COVID-19 vaccine CoronaVac given as the second booster following three doses of CoronaVac: a multicentre, open-label, phase 4, randomised trial

Publikováno v: The Lancet Respiratory Medicine.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ca7c4e263a2643af08ac8ce6166b69c
https://doi.org/10.1016/s2213-2600(23)00049-8

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Safety and Immunogenicity of Aerosolised Ad5-nCoV or Intramuscular Ad5-nCoV or Inactivated COVID-19 Vaccine Coronavac Given as the Second Booster Following Three Doses of CoronaVac: A Multicentre, Open-Label, Phase 4, Randomized Trial

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f8c14f24961530322093a8e7392890e
https://doi.org/10.2139/ssrn.4308756

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Safety and Immunogenicity of Heterologous and Homologous Boosting with Orally Aerosolized or Intramuscular Ad5-nCoV and Inactivated Vaccines in Children and Adolescents: A Randomized, Open-Label, Parallel Controlled, Single-Center Study

Autor: Tao Huang, Sheng Zhang, De-Fang Dai, Bu-Sen Wang, Lu Zhuang, Hai-Tao Huang, Zhongfang Wang, Jun-Shi Zhao, Qiu-Ping Li, Shi-Po Wu, Xue Wang, Wen-Dan Zhang, Zheng-Hao Zhao, Hao Li, Jin-Bo Gou, Li-Hua Hou, Li-Dong Gao, Zhi-Chun Feng

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a41dc92ac9881ea2fbe1e7fb59fcc9b
https://doi.org/10.2139/ssrn.4304747

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Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial

Publikováno v: The Lancet
Lancet (London, England)

Summary Background This is the first randomised controlled trial for assessment of the immunogenicity and safety of a candidate non-replicating adenovirus type-5 (Ad5)-vectored COVID-19 vaccine, aiming to determine an appropriate dose of the candidat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458762bf92f2599b3a9d0199a8fe0e37

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Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial

Publikováno v: The Lancet

Summary Background A vaccine to protect against COVID-19 is urgently needed. We aimed to assess the safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 (Ad5) vectored COVID-19 vaccine expressing the spike glycoprotein of a sev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4b869d3c8bcb53b5fc98d29984a431

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