Increased activation of protein kinase A type I contributes to the T cell deficiency in common variable immunodeficiency

Autor: Aukrust P, Einar Martin Aandahl, Bs, Skålhegg, Nordøy I, Hansson V, Taskén K, Ss, Frøland, Müller F

Publikováno v: Europe PubMed Central
Scopus-Elsevier

The molecular mechanisms underlying the T cell dysfunction often present in common variable immunodeficiency (CVI) are not established. cAMP-dependent protein kinase A type I (PKAI) is an important inhibitor of T cell proliferation after Ag stimulati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdb122fa34cf5633a0fcd86e246349a
https://pubmed.ncbi.nlm.nih.gov/9916750

Structure, function, and regulation of human cAMP-dependent protein kinases

Autor: Taskén K, Bs, Skålhegg, Ka, Taskén, Solberg R, Hk, Knutsen, Fo, Levy, Mårten Sandberg, Orstavik S, Larsen T, Ak, Johansen, Vang T, Hp, Schrader, Nt, Reinton, Km, Torgersen, Hansson V, Jahnsen T

Publikováno v: Europe PubMed Central

A large number of hormones, neurotransmitters, and other signaling substances that bind to G-protein-coupled cell-surface receptors have their signals converge at one sole second messenger, cAMP. The question of how specificity can be maintained in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b2de1b7f9f181d8e5d0a733ffe2ce63d
http://europepmc.org/abstract/med/9344252

The association between body mass index and vulvar and vaginal cancer incidence: findings from a large Norwegian cohort study.

Autor: Aune D; Department of Research, Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway. d.aune@imperial.ac.uk.; Department of Nutrition, Oslo New University College, Oslo, Norway. d.aune@imperial.ac.uk.; Department of Epidemiology and Biostatistics, School of Public Health, White City Campus, 90 Wood Lane, London, W12 0BZ, UK. d.aune@imperial.ac.uk., Nordsletten M; Department of Gastrointestinal and Paediatric Surgery, Oslo University Hospital, Oslo, Norway., Myklebust TÅ; Department of Registration, Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway.; Department of Research and Innovation, Møre and Romsdal Hospital Trust, Ålesund, Norway., Robsahm TE; Department of Research, Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway., Skålhegg BS; Division for Molecular Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway., Mala T; Department of Gastrointestinal and Paediatric Surgery, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, University of Oslo, Oslo, Norway., Yaqub S; Department of Gastrointestinal and Paediatric Surgery, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, University of Oslo, Oslo, Norway., Saeed U; Department of Gastrointestinal and Paediatric Surgery, Oslo University Hospital, Oslo, Norway.

Publikováno v: Cancer causes & control : CCC [Cancer Causes Control] 2024 Oct 27. Date of Electronic Publication: 2024 Oct 27.

Preoperative profiles of plasma amino acids and derivatives distinguish periampullary cancer and benign disease.

Autor: Stålberg SM; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Department of Natural Sciences and Environmental Health, University of South-Eastern Norway, Bø i Telemark, Norway.; Department of Pathology, Skien Hospital, Vestfold og Telemark, Norway., Silwal-Pandit L; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway., Bastani NE; Division for Molecular Nutrition, Institute for Basic Medical Sciences, University of Oslo, Oslo, Norway., Nebdal DJH; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway., Lingjærde OC; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Department of Computer Science, University of Oslo, Oslo, Norway., Skålhegg BS; Division for Molecular Nutrition, Institute for Basic Medical Sciences, University of Oslo, Oslo, Norway., Kure EH; Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway. elin.kure@usn.no.; Department of Natural Sciences and Environmental Health, University of South-Eastern Norway, Bø i Telemark, Norway. elin.kure@usn.no.

Publikováno v: BMC cancer [BMC Cancer] 2024 May 03; Vol. 24 (1), pp. 555. Date of Electronic Publication: 2024 May 03.

Systemic proteome adaptions to 7-day complete caloric restriction in humans.

Autor: Pietzner M; Computational Medicine, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany. maik.pietzner@bih-charite.de.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK. maik.pietzner@bih-charite.de.; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK. maik.pietzner@bih-charite.de., Uluvar B; Computational Medicine, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Kolnes KJ; Department of Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway.; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark., Jeppesen PB; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Frivold SV; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway., Skattebo Ø; Department of Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway., Johansen EI; Department of Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway., Skålhegg BS; Department of Nutrition, Division for Molecular Nutrition, University of Oslo, Oslo, Norway., Wojtaszewski JFP; August Krogh Section for Molecular Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark., Kolnes AJ; Section of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital, Oslo, Norway., Yeo GSH; Metabolic Research Laboratory, Wellcome-MRC Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., O'Rahilly S; Metabolic Research Laboratory, Wellcome-MRC Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK., Jensen J; Department of Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway., Langenberg C; Computational Medicine, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany. claudia.langenberg@qmul.ac.uk.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK. claudia.langenberg@qmul.ac.uk.; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK. claudia.langenberg@qmul.ac.uk.

Publikováno v: Nature metabolism [Nat Metab] 2024 Apr; Vol. 6 (4), pp. 764-777. Date of Electronic Publication: 2024 Mar 01.