The Shigella kinase effector OspG modulates host ubiquitin signaling to escape septin-cage entrapment.

Autor: Xian W; Department of Microbiology and Infectious Disease Center, NHC Key Laboratory of Medical Immunology, School of Basic Medical Sciences, Peking University Health Science Center, 100191, Beijing, China., Fu J; Department of Respiratory Medicine, Center for Infectious Diseases and Pathogen Biology, Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, The First Hospital of Jilin University, 130021, Changchun, China., Zhang Q; Department of Microbiology and Infectious Disease Center, NHC Key Laboratory of Medical Immunology, School of Basic Medical Sciences, Peking University Health Science Center, 100191, Beijing, China., Li C; Department of Biological Sciences, Purdue University, West Lafayette, IN, 47907, USA., Zhao YB; Key Laboratory of Microbial Pathogenesis and Interventions of Fujian Province University, the Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of the Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China., Tang Z; Department of Microbiology and Infectious Disease Center, NHC Key Laboratory of Medical Immunology, School of Basic Medical Sciences, Peking University Health Science Center, 100191, Beijing, China., Yuan Y; Department of Microbiology and Infectious Disease Center, NHC Key Laboratory of Medical Immunology, School of Basic Medical Sciences, Peking University Health Science Center, 100191, Beijing, China., Wang Y; Department of Microbiology and Infectious Disease Center, NHC Key Laboratory of Medical Immunology, School of Basic Medical Sciences, Peking University Health Science Center, 100191, Beijing, China., Zhou Y; Institute of Microbiology, College of Life Sciences, Zhejiang University, 310058, Hangzhou, China., Brzoic PS; Department of Biochemistry, University of Washington, Seattle, WA, 98195, USA., Zheng N; Department of Pharmacology, University of Washington, Seattle, WA, 98195, USA., Ouyang S; Key Laboratory of Microbial Pathogenesis and Interventions of Fujian Province University, the Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of the Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China., Luo ZQ; Department of Biological Sciences, Purdue University, West Lafayette, IN, 47907, USA. luoz@purdue.edu., Liu X; Department of Microbiology and Infectious Disease Center, NHC Key Laboratory of Medical Immunology, School of Basic Medical Sciences, Peking University Health Science Center, 100191, Beijing, China. xiaoyun.liu@bjmu.edu.cn.

Publikováno v: Nature communications [Nat Commun] 2024 May 08; Vol. 15 (1), pp. 3890. Date of Electronic Publication: 2024 May 08.