Dietary supplementation with soluble plantain non-starch polysaccharides inhibits intestinal invasion of Salmonella Typhimurium in the chicken.

Autor: Bryony N Parsons, Paul Wigley, Hannah L Simpson, Jonathan M Williams, Suzie Humphrey, Anne-Marie Salisbury, Alastair J M Watson, Stephen C Fry, David O'Brien, Carol L Roberts, Niamh O'Kennedy, Asa V Keita, Johan D Söderholm, Jonathan M Rhodes, Barry J Campbell

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e87658 (2014)

Soluble fibres (non-starch polysaccharides, NSP) from edible plants but particularly plantain banana (Musa spp.), have been shown in vitro and ex vivo to prevent various enteric pathogens from adhering to, or translocating across, the human intestina

Externí odkaz: https://doaj.org/article/c9650eb50de44dbd8d9db0a1f8f63863

Invasive non-typhoidal Salmonella typhimurium ST313 are not host-restricted and have an invasive phenotype in experimentally infected chickens.

Autor: Bryony N Parsons, Suzanne Humphrey, Anne Marie Salisbury, Julia Mikoleit, Jay C D Hinton, Melita A Gordon, Paul Wigley

Publikováno v: PLoS Neglected Tropical Diseases, Vol 7, Iss 10, p e2487 (2013)

Salmonella enterica serovar Typhimurium Sequence Type (ST) 313 is a major cause of invasive non-Typhoidal salmonellosis in sub-Saharan Africa. No animal reservoir has been identified, and it has been suggested that ST313 is adapted to humans and tran

Externí odkaz: https://doaj.org/article/ab235f1d310749fda1b4a530fa855a67

Netazepide inhibits expression of Pappalysin 2 in type-1 gastric neuroendocrine tumors

Autor: Andrea Varro, Carrie A. Duckworth, Katie A. Lloyd, Yongxiang Fang, Stamatia Papoutsopoulou, Nathan Howes, Klaire Exarchou, Lucille Rainbow, Andrew R. Moore, D. Mark Pritchard, Neil Hall, Claus Oxvig, Michael D. Burkitt, Steven Dodd, Bryony N. Parsons, Malcolm Boyce

Publikováno v: Lloyd, K A, Parsons, B N, Burkitt, M D, Moore, A R, Papoutsopoulou, S, Boyce, M, Duckworth, C A, Exarchou, K, Howes, N, Rainbow, L, Fang, Y, Oxvig, C, Dodd, S, Varro, A, Hall, N & Pritchard, D M 2020, ' Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors ', Cellular and Molecular Gastroenterology and Hepatology, vol. 10, no. 1, pp. 113-132 . https://doi.org/10.1016/j.jcmgh.2020.01.010
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 113-132 (2020)

Background & Aims In patients with autoimmune atrophic gastritis and achlorhydria, hypergastrinemia is associated with the development of type 1 gastric neuroendocrine tumors (gNETs). Twelve months of treatment with netazepide (YF476), an antagonist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7554914bc0596db17395b9f59dbcfa2f
https://ueaeprints.uea.ac.uk/id/eprint/73860/

Comparison of the human gastric microbiota in hypochlorhydric states arising as a result of Helicobacter pylori-induced atrophic gastritis, autoimmune atrophic gastritis and proton pump inhibitor use

Autor: Richard Eccles, Neil Hall, Rosalinda D’Amore, Andrew R. Moore, Andrea Varro, David M. Pritchard, Michael D. Burkitt, Luca Lenzi, Bryony N. Parsons, Carrie A. Duckworth, Umer Zeeshan Ijaz, László Tiszlavicz

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 11, p e1006653 (2017)

Several conditions associated with reduced gastric acid secretion confer an altered risk of developing a gastric malignancy. Helicobacter pylori-induced atrophic gastritis predisposes to gastric adenocarcinoma, autoimmune atrophic gastritis is a prec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e819dc7407d26b9450abc7d4605c4f47
https://pubmed.ncbi.nlm.nih.gov/29095917

Netazepide, a gastrin/CCK2 receptor antagonist, can eradicate gastric neuroendocrine tumours in patients with autoimmune chronic atrophic gastritis

Autor: Reidar Fossmark, David M. Pritchard, Andrea Varro, Bryony N. Parsons, Liv Thomsen, Helge L. Waldum, Andrew R. Moore, Katie A. Lloyd, Liv Sagatun, Malcolm Boyce

Publikováno v: Endocrine Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38682029a0f10e6376c9c13bbbd8447a
https://doi.org/10.1530/endoabs.46.oc1