Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bryony Leeke"'
Autor:
King Hang Tommy Mau, Donja Karimlou, David Barneda, Vincent Brochard, Christophe Royer, Bryony Leeke, Roshni A. de Souza, Mélanie Pailles, Michelle Percharde, Shankar Srinivas, Alice Jouneau, Mark Christian, Véronique Azuara
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Prior to its implantation into the uterus, the mammalian embryo stores substantial lipids. Here the authors unveil how lipid storage and morphogenesis of pluripotent stem cells are fundamentally connected during peri-implantation development.
Externí odkaz:
https://doaj.org/article/bb72511e0105419db55b4a16833beed1
Autor:
Megan Leask, Catherine Carleton, Bryony Leeke, Trent Newman, Joseph Antoun, Mauro Farella, Julia Horsfield
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1964 (2021)
Craniofacial abnormalities are a common group of congenital developmental disorders that can require intensive oral surgery as part of their treatment. Neural crest cells (NCCs) contribute to the facial structures; however, they are extremely sensiti
Externí odkaz:
https://doaj.org/article/123ace989afa4bb4851466d12af7a527
Autor:
Bryony Leeke, Dubravka Cukrov, Megan Leask, Julia A. Horsfield, Antonio Musio, Trent Newman, Ian D. Krantz, Antonie D. Kline, Patrizia Sarogni, Alessandra Patimo
Publikováno v:
Human molecular genetics. 27(17)
Cornelia de Lange syndrome (CdLS) is a rare disease characterized by cognitive impairment, multisystemic alterations and premature aging. Furthermore, CdLS cells display gene expression dysregulation and genomic instability. Here, we demonstrated tha
Publikováno v:
Redox Biology
Exposure to environmental stressors during embryo development can have long-term effects on the adult organism. This study used the thioredoxin reductase inhibitor auranofin to investigate the consequences of oxidative stress during zebrafish develop
Publikováno v:
Experimental Hematology & Oncology
Recently, whole genome sequencing approaches have pinpointed mutations in genes that were previously not associated with cancer. For Acute Myeloid Leukaemia (AML), and other myeloid disorders, these approaches revealed a high prevalence of mutations