Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Brynn R Olden"'
Publikováno v:
Biomaterials Science. 7:789-797
T cells have emerged as a therapeutically-relevant target for ex vivo gene delivery and editing. However, most commercially available reagents cannot transfect T cells and designing cationic polymers for non-viral gene delivery to T cells has resulte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50acfa12b29ec5154af7dd4ac55d53e
https://doi.org/10.1039/c8bm01262h
https://doi.org/10.1039/c8bm01262h
Publikováno v:
Journal of Controlled Release. 282:140-147
The clinical success of chimeric antigen receptor (CAR) T cell immunotherapy in treating multiple blood cancers has created a need for efficient methods of ex vivo gene delivery to primary human T cells for cell engineering. Here, we synthesize and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed6e9cb2bba1e2d1e8b152db2fcffbe
https://doi.org/10.1016/j.jconrel.2018.02.043
https://doi.org/10.1016/j.jconrel.2018.02.043
Autor:
Suzie H. Pun, Stephen J. Salipante, David J. Peeler, James Kevin Y Tan, Drew L. Sellers, Julio Marco B. Pineda, Brynn R Olden, Veronica L. Porubsky
Publikováno v:
ACS Nano
While biologic drugs such as proteins, peptides, or nucleic acids have shown promise in the treatment of neurodegenerative diseases, the blood-brain barrier (BBB) severely limits drug delivery to the central nervous system (CNS) after systemic admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1ae88e0bc02be159f5edeb97d71c4a
https://europepmc.org/articles/PMC7651855/
https://europepmc.org/articles/PMC7651855/
Autor:
Joshua A. Gustafson, Bryan Kaehr, Suzie H. Pun, Ian I. Cardle, Ashley Wilson, Michael C. Jensen, Yu-Shen Lin, Caleb R. Perez, Brynn R Olden
Publikováno v:
Advanced Healthcare Materials. 8:1801188
Biomaterial properties that modulate T cell activation, growth, and differentiation are of significant interest in the field of cellular immunotherapy manufacturing. In this work, we present a new platform technology that allows for the modulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80f3462048f482eb05a9ad3697eee8d
https://doi.org/10.1002/adhm.201801188
https://doi.org/10.1002/adhm.201801188