Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Brynn B Duncan"'
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 17-31 (2022)
Chimeric antigen receptor (CAR)-T cells have emerged as a promising treatment modality for various hematologic and solid malignancies over the past decade. Animal models remain the cornerstone of pre-clinical evaluation of human CAR-T cell products a
Externí odkaz:
https://doaj.org/article/57dca2596edc4fb0a3f3e1e81bf202e8
Autor:
Brynn B Duncan, Jennifer Lotter, Jeanine Superata, Ma Evette Barranta, Ivana Darden, Sanjay Venugopal, Colin O. Wu, Cynthia E. Dunbar, David J. Young
Publikováno v:
Blood. 140:5824-5825
Autor:
Seena Tabibi, Sonia Kamanda, Nicolas Llosa, Christine A. Pratilas, Brynn B. Duncan, Rodrigo Salgado Esteves, Andres Matoso
Publikováno v:
Applied immunohistochemistrymolecular morphology : AIMM. 31(1)
We present an 18-year-old male patient who presented with a 16 cm testicular tumor alongside multiple lesions in the lungs, right pelvis with involvement of the ischio/pubic bone, and enlarged pelvic lymph nodes on imaging, suspicious for metastatic
Autor:
Brynn B. Duncan, Justin Mirazee, Christopher Chien, Stefan Cordes, Sogun Hong, Noriko Sato, David Young, Cynthia E. Dunbar
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S187
Autor:
Brynn B. Duncan, Justin Mirazee, Christopher Chien, Stefan Cordes, Sogun Hong, Noriko Sato, David Young, Cynthia E. Dunbar
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S437
Autor:
Chad R. Burk, Kazusa Ishii, Sang M. Nguyen, Paul Su, Bong Hyun Kim, Terry J. Fry, Nirali N. Shah, Haiying Qin, M. Eric Kohler, Samikasha Tarun, Brynn B. Duncan
Publikováno v:
Blood. 132:1899-1910
Adoptive transfer of patient-derived T cells modified to express chimeric antigen receptors (CARTs) has demonstrated dramatic success in relapsed/refractory pre-B-cell acute lymphoblastic leukemia (ALL), but response and durability of remission requi
Publikováno v:
Current hematologic malignancy reports. 13(5)
Genetically engineered T cells expressing a chimeric antigen receptor (CAR-T) targeting specific antigens present on acute lymphoblastic leukemia (ALL) blasts have generated promising results in children and adults with relapsed and refractory diseas
Autor:
Terry J. Fry, James W. Hodge, Wengen Wu, Renee N. Donahue, Jack H. Lai, Peng Zhao, Kwong-Yok Tsang, Christopher P. Kiritsy, Barry Jones, Yuxin Liu, William W. Bachovchin, Brynn B. Duncan
Publikováno v:
Vaccine. 32:3223-3231
Recent studies have suggested that pan inhibitors of dipeptidyl peptidase-4 activity and/or structure homologs (DASH), including ARI-4175, can mediate tumor regression by immune-mediated mechanisms. This study assessed the potential of combining ARI-
Autor:
Terry J. Fry, Jack H. Lai, Barry Jones, Iwona Woznica, Yuxin Liu, Najat Bouchkouj, Shannon M. Larabee, Haiying Qin, Crystal L. Mackall, Brynn B. Duncan, Steven L. Highfill, William W. Bachovchin, Wengen Wu, Youhua Li, Peng Zhao
Publikováno v:
Journal of Immunotherapy. 36:400-411
Current multimodality therapy consisting of surgery, chemotherapy and radiation will fail in approximately 40% of patients with pediatric sarcomas and results in substantial long-term morbidity in those who are cured. Immunotherapeutic regimens for t
Autor:
Terry J. Fry, Meghaan P. Walsh, Martin Guimond, Jessica P. E. Davis, Shannon M. Larabee, Yongzhi Cui, William W. Bachovchin, Brynn B. Duncan, Su Young Kim, Aviva C. Krauss
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58860 (2013)
PLoS ONE
PLoS ONE
Although tumors naturally prime adaptive immune responses, tolerance may limit the capacity to control progression and can compromise effectiveness of immune-based therapies for cancer. Post-proline cleaving enzymes (PPCE) modulate protein function t