Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Bryce P. Johnson"'
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 1, Pp 97-106 (2024)
AIM: To assess diabetic macular edema (DME) progression during the early phases of the COVID-19 pandemic, when severe societal restrictions raised the concern of possible deterioration of health in patients with systemic conditions, particularly thos
Externí odkaz:
https://doaj.org/article/508e536833a542cebfef11f1b8bf3832
Autor:
Bryce P. Johnson, Vikas Kumar, Erin M. Scull, Leonard M. Thomas, Christina R. Bourne, Shanteri Singh
Publikováno v:
ACS Chem Biol
Isopentenyl phosphate kinases (IPKs) catalyze the ATP-dependent phosphorylation of isopentenyl monophosphate (IP) to isopentenyl diphosphate (IPP) in the alternate mevalonate pathways of the archaea and plant cytoplasm. In recent years, IPKs have als
Publikováno v:
ChemCatChem
The widespread utility of isoprenoids has recently sparked interest in efficient synthesis of isoprene-diphosphate precursors. Current efforts have focused on evaluating two-step “isoprenol pathways,” which phosphorylate prenyl alcohols using pro
Autor:
Ken Dower, Shanrong Zhao, Franklin J Schlerman, Leigh Savary, Gabriela Campanholle, Bryce G Johnson, Li Xi, Vuong Nguyen, Yutian Zhan, Matthew P Lech, Ju Wang, Qing Nie, Morten A Karsdal, Federica Genovese, Germaine Boucher, Thomas P Brown, Baohong Zhang, Bruce L Homer, Robert V Martinez
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181861 (2017)
ZSF1 rats exhibit spontaneous nephropathy secondary to obesity, hypertension, and diabetes, and have gained interest as a model system with potentially high translational value to progressive human disease. To thoroughly characterize this model, and
Externí odkaz:
https://doaj.org/article/c8649b6e74a94a41b0cb26d57a6ac938
Autor:
Eric D Gardner, Bryce P. Johnson, Dustin A Dimas, Andrea L Batchev, Susan L. Nimmo, Tejaswi Bavineni, Shanteri Singh, Erin M. Scull, Chandrasekhar Bandari
Publikováno v:
Applied Microbiology and Biotechnology
Abstract Aromatic prenyltransferases are known for their extensive promiscuity toward aromatic acceptor substrates and their ability to form various carbon-carbon and carbon-heteroatom bonds. Of particular interest among the prenyltransferases is Nph
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146697 (2016)
Hypertrophic cardiomyopathy (HCM) is a leading cause of sudden cardiac death that often goes undetected in the general population. HCM is also prevalent in patients with cardio-facio-cutaneous syndrome (CFCS), which is a genetic disorder characterize
Externí odkaz:
https://doaj.org/article/30a3f1c19404425d8de4937e94eefa51
Autor:
Jianlan You, Eric D Gardner, Bryce P. Johnson, Robert H. Cichewicz, Marco Tonelli, Chandrasekhar Bandari, Erin M. Scull, Shanteri Singh
Publikováno v:
Applied Microbiology and Biotechnology
Abstract Daptomycin is a last resort antibiotic for the treatment of infections caused by many Gram-positive bacterial strains, including vancomycin-resistant Enterococcus (VRE) and methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA an
Autor:
Grover P. Miller, Linda P. Desrochers, Dustyn A. Barnette, Robert Nshimiyimana, Dakota L. Pouncey, Bryce P. Johnson, Thomas E. Goodwin
Coumadin (rac-warfarin) is the most commonly used anticoagulant in the world; however, its clinical use is often challenging because of its narrow therapeutic range and interindividual variations in response. A critical contributor to the uncertainty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e7911173bf59a859dddd3edf5eca58
https://europepmc.org/articles/PMC5539582/
https://europepmc.org/articles/PMC5539582/
Autor:
Yeawon Kim, Chuang Li, Chenjian Gu, Yili Fang, Eric Tycksen, Anuradhika Puri, Terri A. Pietka, Jothilingam Sivapackiam, Kendrah Kidd, Sun-Ji Park, Bryce G. Johnson, Stanislav Kmoch, Jeremy S. Duffield, Anthony J. Bleyer, Meredith E. Jackrel, Fumihiko Urano, Vijay Sharma, Maria Lindahl, Ying Maggie Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Misfolded protein aggregates may cause toxic proteinopathy, including autosomal dominant tubulointerstitial kidney disease due to uromodulin mutations (ADTKD-UMOD), a leading hereditary kidney disease. There are no targeted therapies. In our
Externí odkaz:
https://doaj.org/article/72c2d4d2fcd54509bc61bc5046fee857
Autor:
Ju Wang, Agustin Casimiro-Garcia, Bryce G. Johnson, Jennifer Duffen, Michael Cain, Leigh Savary, Stephen Wang, Prashant Nambiar, Matthew Lech, Shanrong Zhao, Li Xi, Yutian Zhan, Jennifer Olson, James A. Stejskal, Hank Lin, Baohong Zhang, Robert V. Martinez, Katherine Masek-Hammerman, Franklin J. Schlerman, Ken Dower
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Type 2 diabetes (T2D) and its complications can have debilitating, sometimes fatal consequences for afflicted individuals. The disease can be difficult to control, and therapeutic strategies to prevent T2D-induced tissue and organ damage are
Externí odkaz:
https://doaj.org/article/794a53c2283d4e51a4aee2e57be81772