Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Bryce M Warner"'
Autor:
Shawna L Semple, Tamiru N Alkie, Kristof Jenik, Bryce M Warner, Nikesh Tailor, Darwyn Kobasa, Stephanie J DeWitte-Orr
Publikováno v:
Virus Research, Vol 321, Iss , Pp 198925- (2022)
Human coronaviruses (HCoVs) are important human pathogens, as exemplified by the current SARS-CoV-2 pandemic. While the ability of type I interferons (IFNs) to limit coronavirus replication has been established, the ability of double-stranded (ds)RNA
Externí odkaz:
https://doaj.org/article/c2bef6670deb48bcb512672a48356bae
Autor:
Derek R Stein, Bryce M Warner, Jonathan Audet, Geoff Soule, Vinayakumar Siragam, Patrycja Sroga, Bryan D Griffin, Anders Leung, Allen Grolla, Kevin Tierney, Alix Albietz, Darwyn Kobasa, Abdulmajid S Musa, Adama Ahmad, Afolabi M Akinpelu, Nwando Mba, Rebecca Rosenke, Dana P Scott, Greg Saturday, Chikwe Ihekweazu, David Safronetz
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009966 (2021)
Nigeria continues to experience ever increasing annual outbreaks of Lassa fever (LF). The World Health Organization has recently declared Lassa virus (LASV) as a priority pathogen for accelerated research leading to a renewed international effort to
Externí odkaz:
https://doaj.org/article/9f82772fd3584798b0bfe017968a7c73
Autor:
Bryce M Warner, Derek R Stein, Rohit K Jangra, Megan M Slough, Patrycja Sroga, Angela Sloan, Kathy L Frost, Stephanie Booth, Kartik Chandran, David Safronetz
Publikováno v:
Viruses, Vol 11, Iss 7, p 645 (2019)
Andes virus (ANDV) and Sin Nombre virus (SNV) are the main causative agents responsible for hantavirus cardiopulmonary syndrome (HCPS) in the Americas. HCPS is a severe respiratory disease with a high fatality rate for which there are no approved the
Externí odkaz:
https://doaj.org/article/9ce9ee8a9bd0440bb083861ddee670ad
Autor:
Elizabeth M. Parzych, Jianqiu Du, Ali R. Ali, Katherine Schultheis, Drew Frase, Trevor R. F. Smith, Jiayan Cui, Neethu Chokkalingam, Nicholas J. Tursi, Viviane M. Andrade, Bryce M. Warner, Ebony N. Gary, Yue Li, Jihae Choi, Jillian Eisenhauer, Igor Maricic, Abhijeet Kulkarni, Jacqueline D. Chu, Gabrielle Villafana, Kim Rosenthal, Kuishu Ren, Joseph R. Francica, Sarah K. Wootton, Pablo Tebas, Darwyn Kobasa, Kate E. Broderick, Jean D. Boyer, Mark T. Esser, Jesper Pallesen, Dan W. Kulp, Ami Patel, David B. Weiner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Here, Parzych et al describe the development of a DNA-delivered SARS-CoV-2 mAb cocktail displaying synergistic RBD binding that confers broad neutralizing activity against variants of concern and prophylactic efficacy in multiple small animal models.
Externí odkaz:
https://doaj.org/article/dec1ebc23ee2448fb7ad32d2457e1b56
Autor:
Kaye Quizon, Kimberly Holloway, Mahmood Iranpour, Bryce M. Warner, Yvon Deschambault, Geoff Soule, Kevin Tierney, Darwyn Kobasa, Angela Sloan, David Safronetz
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 9, Pp 1882-1885 (2022)
We demonstrate that 6 distinct Peromyscus rodent species are permissive to experimental infection with Sin Nombre orthohantavirus (SNV). Viral RNA and SNV antibodies were detected in members of all 6 species. P. leucopus mice demonstrated markedly hi
Externí odkaz:
https://doaj.org/article/62cfceb8c9194741a1039bd12835caeb
Autor:
Ebony N. Gary, Nicholas J. Tursi, Bryce M. Warner, Gina Cuismano, Jennifer Connors, Elizabeth M. Parzych, Bryan D. Griffin, Matthew R. Bell, Ali R. Ali, Drew Frase, Casey E. Hojecki, Gabriela A. Canziani, Irwin Chaiken, Toshitha Kannan, Estella Moffat, Carissa Embury-Hyatt, Sarah K. Wooton, Andrew Kossenkov, Ami Patel, Darwyn Kobasa, Michele A. Kutzler, Elias K. Haddad, David B. Weiner
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Despite numerous clinically available vaccines and therapeutics, aged patients remain at increased risk for COVID-19 morbidity. Furthermore, various patient populations, including the aged can have suboptimal responses to SARS-CoV-2 vaccine antigens.
Externí odkaz:
https://doaj.org/article/54e6d5648e304ae68b9b6bf090ee114c
Autor:
Lauren Garnett, Kaylie N. Tran, Zachary Schiffman, Kristina A. Muise, Quinn E. Fletcher, Yvonne A. Dzal, Anders Leung, Alix Albietz, Bryce M. Warner, Bryan D. Griffin, Darwyn Kobasa, Craig K. R. Willis, James E. Strong
Publikováno v:
Viruses, Vol 15, Iss 9, p 1827 (2023)
Ebola virus is a zoonotic pathogen with a geographic range covering diverse ecosystems that are home to many potential reservoir species. Although researchers have detected Ebola virus RNA and serological evidence of previous infection in different r
Externí odkaz:
https://doaj.org/article/663c64bdbd12417ebba3c4219a54d1d0
Autor:
Bryce M. Warner, Sebastian Dowhanik, Jonathan Audet, Allen Grolla, Daryl Dick, James E. Strong, Darwyn Kobasa, L. Robbin Lindsay, Gary Kobinger, Heinz Feldmann, Harvey Artsob, Michael A. Drebot, David Safronetz
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 12, Pp 3020-3024 (2020)
Hantavirus cardiopulmonary syndrome (HCPS) is a severe respiratory disease caused by Sin Nombre virus in North America (SNV). As of January 1, 2020, SNV has caused 143 laboratory-confirmed cases of HCPS in Canada. We review critical aspects of SNV vi
Externí odkaz:
https://doaj.org/article/30dab0d5268241c3ab080cde86170c0e
Autor:
Nikesh Tailor, Bryce M. Warner, Bryan D. Griffin, Kevin Tierney, Estella Moffat, Kathy Frost, Robert Vendramelli, Anders Leung, Marnie Willman, Sylvia P. Thomas, Yanlong Pei, Stephanie A. Booth, Carissa Embury-Hyatt, Sarah K. Wootton, Darwyn Kobasa
Publikováno v:
Viruses, Vol 15, Iss 1, p 85 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of coronavirus disease 2019 (COVID-19) that has caused a pandemic with millions of human infections. There continues to be a pressing need to develop potential the
Externí odkaz:
https://doaj.org/article/c282f1928b30468bada1eb6ce5ae4f2a
Autor:
Ebony N. Gary, Bryce M. Warner, Elizabeth M. Parzych, Bryan D. Griffin, Xizhou Zhu, Nikesh Tailor, Nicholas J. Tursi, Mable Chan, Mansi Purwar, Robert Vendramelli, Jihae Choi, Kathy L. Frost, Sophia Reeder, Kevin Liaw, Edgar Tello, Ali R. Ali, Kun Yun, Yanlong Pei, Sylvia P. Thomas, Amira D. Rghei, Matthew M. Guilleman, Kar Muthumani, Trevor Smith, Sarah K. Wootton, Ami Patel, David B. Weiner, Darwyn Kobasa
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102699- (2021)
Summary: More than 100 million people have been infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Common laboratory mice are not susceptible to wild-type SARS-CoV-2 infection, challenging the development and testing of effec
Externí odkaz:
https://doaj.org/article/c729d41c6d47484fbcc09aab37def4d6