Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Bryce M, Paschal"'
Autor:
Chun-Song Yang, Kasey Jividen, Teddy Kamata, Natalia Dworak, Luke Oostdyk, Bartlomiej Remlein, Yasin Pourfarjam, In-Kwon Kim, Kang-Ping Du, Tarek Abbas, Nicholas E. Sherman, David Wotton, Bryce M. Paschal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Androgen receptor (AR) signaling is regulated by multiple post-translational modifications. Here, the authors identify the writer and reader enzymes for AR ADP-ribosylation and show how they modulate AR signaling output in prostate cancer cells.
Externí odkaz:
https://doaj.org/article/4e3161d87a9e495bb19ec9d697ca2a8c
Autor:
Pedro Costa-Pinheiro, Abigail Heher, Michael H. Raymond, Kasey Jividen, Jeremy JP. Shaw, Bryce M. Paschal, Susan J. Walker, Todd E. Fox, Mark Kester
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101855- (2020)
Summary: Anti-androgens are a common therapy in prostate cancer (PCa) targeting androgen receptor (AR) signaling. However, these therapies fail due to selection of highly aggressive AR-negative cancer cells that have no therapeutic options available.
Externí odkaz:
https://doaj.org/article/e195566108ee4580971a934e8bc4e80d
Autor:
Jiekun Yang, Xiaolong Wei, Turan Tufan, Cem Kuscu, Hayrunnisa Unlu, Saadia Farooq, Elif Demirtas, Bryce M. Paschal, Mazhar Adli
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-15 (2018)
Abstract Background The mutational processes underlying non-coding cancer mutations and their biological significance in tumor evolution are poorly understood. To get better insights into the biological mechanisms of mutational processes in breast ca
Externí odkaz:
https://doaj.org/article/5400a3be0d2d456a8c2bb7c7e8aad587
Autor:
Kasey Jividen, Katarzyna Z Kedzierska, Chun-Song Yang, Karol Szlachta, Aakrosh Ratan, Bryce M Paschal
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-20 (2018)
Abstract Background The cellular effects of androgen are transduced through the androgen receptor, which controls the expression of genes that regulate biosynthetic processes, cell growth, and metabolism. Androgen signaling also impacts DNA damage si
Externí odkaz:
https://doaj.org/article/625c892f6d7a4c4bb77816004edbcc85
Autor:
Bryce M Paschal, David Wotton, Aakrosh Ratan, Tarek Abbas, Justin M Drake, Nicki Abianeh, Sachi B Tengse, Song Yi Bae, Natalia M Dworak, Krzysztof Wierbilowicz, Chunsong Yang
Extendend analysis of PARP7 expression in prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03590069a40be835a1343ac1296947ea
https://doi.org/10.1158/2767-9764.22644768
https://doi.org/10.1158/2767-9764.22644768
Autor:
Bryce M Paschal, David Wotton, Aakrosh Ratan, Tarek Abbas, Justin M Drake, Nicki Abianeh, Sachi B Tengse, Song Yi Bae, Natalia M Dworak, Krzysztof Wierbilowicz, Chunsong Yang
FACS analysis of NCI-H660 cells for detection of necrosis and apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00cfa0e64334d0f2508ac53d2142735
https://doi.org/10.1158/2767-9764.22644771.v1
https://doi.org/10.1158/2767-9764.22644771.v1
Autor:
Bryce M. Paschal, David Wotton, Aakrosh Ratan, Tarek Abbas, Justin M. Drake, Nicki Abianeh, Sachi B. Tengse, Song Yi Bae, Natalia M. Dworak, Krzysztof Wierbiłowicz, Chunsong Yang
Supplementary Table 1: RBN2397 growth effects in prostate cencer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854b057049a9ae1504baf7a3d7d66e8c
https://doi.org/10.1158/2767-9764.22644765.v1
https://doi.org/10.1158/2767-9764.22644765.v1
Autor:
Bryce M Paschal, David Wotton, Aakrosh Ratan, Tarek Abbas, Justin M Drake, Nicki Abianeh, Sachi B Tengse, Song Yi Bae, Natalia M Dworak, Krzysztof Wierbilowicz, Chunsong Yang
RBN2397 inhibition of prostate cancer cell growth requires PARP7 over-expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725aab61aa4798baccf09d10e180f972
https://doi.org/10.1158/2767-9764.22644774.v1
https://doi.org/10.1158/2767-9764.22644774.v1
Autor:
Bryce M Paschal, David Wotton, Aakrosh Ratan, Tarek Abbas, Justin M Drake, Nicki Abianeh, Sachi B Tengse, Song Yi Bae, Natalia M Dworak, Krzysztof Wierbilowicz, Chunsong Yang
Cell cycle distributions of cell lines treated with RBN2397 plus androgen or plus AHR agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6755e15af235581861c48855cc512249
https://doi.org/10.1158/2767-9764.22644783.v1
https://doi.org/10.1158/2767-9764.22644783.v1
Autor:
Bryce M Paschal, David Wotton, Aakrosh Ratan, Tarek Abbas, Justin M Drake, Nicki Abianeh, Sachi B Tengse, Song Yi Bae, Natalia M Dworak, Krzysztof Wierbilowicz, Chunsong Yang
BBQ and FICZ treatment activates AHR signaling in prostate cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d09b3dc071a54ab59a414e76d4f5b8
https://doi.org/10.1158/2767-9764.22546816
https://doi.org/10.1158/2767-9764.22546816