Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Bryce Chackerian"'
Autor:
Bryce Chackerian, Alan T. Remaley
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 3, Pp 100524- (2024)
Externí odkaz:
https://doaj.org/article/14c99cc03e3c4637937d96018bc4007f
Autor:
Alexandra Fowler, Koen K. A. Van Rompay, Maureen Sampson, Javier Leo, Jennifer K. Watanabe, Jodie L. Usachenko, Ramya Immareddy, Debbie M. Lovato, John T. Schiller, Alan T. Remaley, Bryce Chackerian
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract Elevated low-density lipoprotein cholesterol (LDL-C) is an important risk factor in the development of atherosclerotic cardiovascular disease (ASCVD). Inhibitors of proprotein convertase subtilisin/kexin type 9 (PCSK9), a negative regulator
Externí odkaz:
https://doaj.org/article/facb55d5a57b495fafe7c6f7e035a99f
Autor:
Wei-Yun Wholey, Alexander R. Meyer, Sekou-Tidiane Yoda, Bryce Chackerian, Julie Zikherman, Wei Cheng
Publikováno v:
Vaccines, Vol 12, Iss 4, p 405 (2024)
The durability of an antibody (Ab) response is highly important for antiviral vaccines. However, due to the complex compositions of natural virions, the molecular determinants of Ab durability from viral infection or inactivated viral vaccines have b
Externí odkaz:
https://doaj.org/article/dd9763b57da646d294af30001ce27cd7
Autor:
Lucie Jelínková, Yevel Flores-Garcia, Sarah Shapiro, Bryce T. Roberts, Nikolai Petrovsky, Fidel Zavala, Bryce Chackerian
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-4 (2022)
Abstract Pre-erythrocytic malaria vaccines that induce high-titer, durable antibody responses can potentially provide protection from infection. Here, we engineered a virus-like particle (VLP)-based vaccine targeting a recently described vulnerable e
Externí odkaz:
https://doaj.org/article/cf778b5a6ac440b8a161c99bff921356
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract A malaria vaccine that elicits long-lasting protection and is suitable for use in endemic areas remains urgently needed. Here, we assessed the immunogenicity and prophylactic efficacy of a vaccine targeting a recently described epitope on th
Externí odkaz:
https://doaj.org/article/e544d49001a446b4988b1be4f00da6f4
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 202 (2023)
Maternal antibodies are passively transferred to the fetus via the placenta during gestation and can play an important role in protecting the newborn from infection. For example, in malaria-endemic regions, maternal antibodies likely provide substant
Externí odkaz:
https://doaj.org/article/85c6bda34b00459d8e32930dcd46fe1b
Autor:
Larance Ronsard, Ashraf S. Yousif, Julianne Peabody, Vintus Okonkwo, Pascal Devant, Alemu Tekewe Mogus, Ralston M. Barnes, Daniel Rohrer, Nils Lonberg, David Peabody, Bryce Chackerian, Daniel Lingwood
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The ligand-binding surface of the B cell receptor (BCR) is formed by encoded and non-encoded antigen complementarity determining regions (CDRs). Genetically reproducible or ‘public’ antibodies can arise when the encoded CDRs play deterministic ro
Externí odkaz:
https://doaj.org/article/c501fb4e290e4b8e90012f7b9a25ca18
Autor:
Nitesh K. Kunda, Julianne Peabody, Lukai Zhai, Dominique N. Price, Bryce Chackerian, Ebenezer Tumban, Pavan Muttil
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 7-8, Pp 1995-2002 (2019)
High-risk human papillomavirus (HPV) types are responsible for nearly all cases of cervical cancers. Cervarix® and Gardasil® 9 are the current prophylactic vaccines available that protect against the majority of HPVs associated with cancer. Althoug
Externí odkaz:
https://doaj.org/article/5b9b814e0e6b4b14a9dde8157f9d0fd4
Publikováno v:
Expert Review of Vaccines, Vol 17, Iss 11, Pp 959-966 (2018)
Introduction: Chlamydia trachomatis (Ct), the most common bacterial sexually transmitted infection (STI), leads to pelvic inflammatory disease, infertility, and ectopic pregnancy in women. In this Perspective, we discuss the successful human papillom
Externí odkaz:
https://doaj.org/article/51c92d58226d41e6abab97e60f875eb6
Autor:
Amanda L. Collar, Alexandria C. Linville, Susan B. Core, Cosette M. Wheeler, William M. Geisler, David S. Peabody, Bryce Chackerian, Kathryn M. Frietze
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT Chlamydia trachomatis is an obligate intracellular bacterium. C. trachomatis infection is the most prevalent bacterial sexually transmitted infection and can lead to pelvic inflammatory disease and infertility in women. There is no licensed
Externí odkaz:
https://doaj.org/article/de85351e32a747c9b8d074350c14fb15